Navigation Links
Zysolin(TM) Pre-clinical Data Supports Once-a-day Dosing in Humans
Date:6/18/2009

    AlphaRx's inhaled Tobramycin nanoparticle formulation provides 300% more
    availability than standard free drug in lung tissue, as demonstrated in a
    recent animal pharmacokinetic study.

MARKHAM, ON, June 18 /PRNewswire-FirstCall/ - AlphaRx (OTC BB:ALRX) is pleased to report a significant breakthrough in the development of Zysolin(TM), an inhaled Tobramycin nanoparticle formulation utilizing the company's proprietary drug delivery platform, and intended for the adjunctive treatment of Pseudomonas Aeruginosa Pneumonia in intubated and mechanically-ventilated patients (VAP).

In a recent pivotal animal PK (pharmacokinetic) study, Zysolin(TM) delivered 300% more drug to lung tissue than free drug, when utilizing the same delivery method. This data demonstrates that Zysolin(TM) provides superior lung tissue penetration and a release profile which supports once-a-day human dosing frequency.

The study data will be presented, by invitation, to the upcoming July meeting of the Controlled Release Society Conference in Copenhagen, Denmark.

Dr. Michael Weisspapir, MD, PhD, Chief Medical Scientist of AlphaRx commented, "As a result of this pre-clinical data, we anticipate that the demonstrated superiority over free drug availability will result in higher drug concentrations in lung tissue, enhancing clinical efficacy for VAP patients in vivo."

About Zysolin(TM)

Zysolin(TM) is a Tobramycin compound, encapsulated in AlphaRx's Nano Drug Delivery Platform, intended for the adjunctive treatment of Gram-negative pneumonia in intubated and mechanically-ventilated patients. Zysolin(TM) improves the intracellular activity of Tobramycin - in layman's term, increasing the drug concentration of Tobramycin inside human macrophages, thus improving its antibacterial activity against intracellular Klebsiella, Pseudomondas aeruginosa and Staphylococcus bacterial strains in pneumonia patients. The
'/>"/>

SOURCE AlphaRx Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine news :

1. PointCross Releases Pre-Clinical Study Lifecycle and Data Management Suite (PC-LDM(TM)) For Multi-Party Environments
2. Data Show SuperGens Multi-Targeted Tyrosine Kinase Inhibitor Demonstrates Pre-clinical Activity in Glioblastoma Multiforme
3. Akela Pharma receives letter from the FDA regarding its pre-clinical toxicology studies for Fentanyl TAIFUN(R)
4. Bioniche Presents Pre-Clinical Research at Two International Conferences
5. Senesco Announces Results of Pre-Clinical Efficacy, Toxicology and Dose Ranging Studies for Multiple Myeloma Therapeutic Candidate
6. Drug inhibits neuroblastoma blood supply in pre-clinical tests
7. Drug therapy reduces neuroblastoma tumor growth in pre-clinical investigation
8. HealthFitness CEO Supports Move Toward Cultural Shift, and Science-Based Health Management Programming
9. Diageo Supports First Ever National We Dont Serve Teens Week
10. The Prem Rawat Foundation Supports Disaster-Relief Efforts in Mozambique
11. Discovery supports theory of Alzheimers disease as form of diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/27/2015)... ... July 27, 2015 , ... The Maricopa Community Colleges ... the foster care system to get into and complete college. , The “Bridging ... at an event today with partners from across the valley. , The initiative advisory ...
(Date:7/27/2015)... NY (PRWEB) , ... July 27, 2015 , ... ... tour. He will be performing for one additional night at each of his ... promo/coupon code DAVID-GILMOUR-2016 for added savings. , David Gilmour’s 2016 North America tour dates: ...
(Date:7/27/2015)... ... July 27, 2015 , ... ... professional and in-depth research report. The report provides basic information such as ... etc. This report covers the global (US, Europe, Japan etc) industry analysis ...
(Date:7/27/2015)... ... July 27, 2015 , ... With a new charity program ... to support its mission of reducing the number of deaths and injuries occurring from ... and their families. PursuitSAFETY works with the police to find better and safer ...
(Date:7/27/2015)... ... July 27, 2015 , ... Throughout its 20 year history, Doctors on ... working on a lien basis. As the personal injury and medical industries have ... chiropractors, to orthopedists, to pain management physicians, to psychologists and more. And while ...
Breaking Medicine News(10 mins):Health News:Maricopa Community Colleges Launch Program To Help Youth In Foster Care Finish College 2Health News:Maricopa Community Colleges Launch Program To Help Youth In Foster Care Finish College 3Health News:Cheap David Gilmour Tickets at Madison Square Garden (MSG), Air Canada Center, United Center and Hollywood Bowl: Additional Dates for David Gilmour Go On Sale Today 2Health News:Calcium Propionate Market Global Suppliers and Manufacture Analysis 2Health News:Calcium Propionate Market Global Suppliers and Manufacture Analysis 3Health News:Gary Short & Associates in Chico, CA Initiates Charity Campaign to Collaborate with National Nonprofit PursuitSAFETY 2Health News:Gary Short & Associates in Chico, CA Initiates Charity Campaign to Collaborate with National Nonprofit PursuitSAFETY 3Health News:Doctors on Liens Adds Highly Respected Physical Therapy Office in Los Angeles 2
... students finds 20% took substances without approval , , MONDAY, ... non-medical use of frequently abused prescription drugs increases the ... study. , Researcher Sean Esteban McCabe asked 3,639 college ... non-prescribed use of four classes of prescription drugs -- ...
... clear association, but no such link for depression , , MONDAY, ... help bring on a stroke may have merit, British researchers ... groups according to how severe their stress is, someone in ... 40 percent increased risk of stroke than someone in the ...
... New York physicians,facing a potential surcharge in malpractice insurance ... an expected one thousand New,York physicians will be in ... Tuesday, March 4th where they will be addressed by ... Capitol steps by 12:30 p.m. to demand,justice and malpractice ...
... BIRMINGHAM, Ala., March 3 Emageon Inc.,(Nasdaq: ... technology,systems for hospitals, healthcare networks and imaging facilities ... will present at the,Raymond James 29th Annual Institutional ... Regency Grand Cypress, Orlando, Florida. Emageon will,present on ...
... ... Today 5,000 Nurses at 11 ... In an atmosphere that nurses,describe as attempted "intimidation" from Sutter ... authorize,their bargaining teams to strike the hospital chain for up to ...
... Rally Behind California Assembly Bills Protecting State,s,Elderly ... SACRAMENTO, Calif., March 3 California,seniors ... Senior Living have,teamed up with advocates and ... increases, and to address serious problems with ...
Cached Medicine News:Health News:Non-Medical Use of Prescriptions Linked to Drug Abuse Risk 2Health News:Stress Can Help Trigger Stroke 2Health News:Attention New York: Please Don't Get Sick on March 4th, Your Doctor Will be in Albany for Malpractice Insurance Reform 2Health News:In Face of Hostile Bargaining and Intimidation by Management, Mills-Peninsula to Vote to Authorize Strike 2Health News:In Face of Hostile Bargaining and Intimidation by Management, Mills-Peninsula to Vote to Authorize Strike 3Health News:'Atria Bills' Get Support From Assisted Living Residents, Family Members, Senior Groups 2
(Date:7/27/2015)... , July 20, 2015 ... announced the addition of the "Cardiometabolic Drug ... Afrezza,s discounted pricing is in line with ... critical to the product,s commercial appeal. However, contraindications, ... Afrezza from gaining a sizeable share of the ...
(Date:7/27/2015)... , July 27, 2015  Linear accelerators used ... machines, requiring not only adequate space for the ... their operation. Inherent to the size and complexity ... accelerator or the addition of a new vault ... operations risks interruption of patient treatment: with potential ...
(Date:7/27/2015)... -- Research and Markets ( http://www.researchandmarkets.com/research/65t478/gprotein_coupled ) has ... Receptors Market: Global Industry Analysis, Size, Share, Growth, ... to their offering. The global ... assay type, therapeutic area, and geography. Based on ... into six major segments: cAMP assays, calcium level ...
Breaking Medicine Technology:Cardiometabolic Drug News Issue - Afrezza Aggressive Pricing Strategy View Playing Out 2Cardiometabolic Drug News Issue - Afrezza Aggressive Pricing Strategy View Playing Out 3Accelerating the Design Process for Cancer Treatment Centers 2Accelerating the Design Process for Cancer Treatment Centers 3G-Protein Coupled Receptors Market: Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2022 2
... Phase II trial of a single,intraoperative administration of ... in the first 8 to 24 hours following,surgery, ... treatment.,The results of the multicenter, randomized, double-blind study ... Assembly in Anesthesiology in New York,City today, by ...
... Canada, Dec. 12 /PRNewswire-FirstCall/ - YM BioSciences Inc. ... that identifies, develops and commercializes differentiated products for ... CIMYM BioSciences Inc. received a milestone payment from ... of the recent marketing approval of nimotuzumab in ...
Cached Medicine Technology:Positive Phase II Study of Pacira's EXPAREL(TM) (DepoBupivacaine) in Hernia Repair Presented at the Postgraduate Assembly in Anesthesiology (PGA) 2Positive Phase II Study of Pacira's EXPAREL(TM) (DepoBupivacaine) in Hernia Repair Presented at the Postgraduate Assembly in Anesthesiology (PGA) 3Positive Phase II Study of Pacira's EXPAREL(TM) (DepoBupivacaine) in Hernia Repair Presented at the Postgraduate Assembly in Anesthesiology (PGA) 4YM BioSciences Announces Milestone Payment For Approval Of Nimotuzumab In The Philippines And Indonesia 2YM BioSciences Announces Milestone Payment For Approval Of Nimotuzumab In The Philippines And Indonesia 3YM BioSciences Announces Milestone Payment For Approval Of Nimotuzumab In The Philippines And Indonesia 4
PRINCIPLE: The QC-SLIDES™ are specifically designed microscope slides intended to be part of the quality control program to monitor microbiological stains and staining techniques....
Microbiology QC Slides come with one or two droplets of an air-dried and methanol-fixed microorganism, or a single smear containing a designated microorganism population....
Each slide contains a high yield of concentrated C. parvum oocysts within the positive control well. A negative control well is also included....
... 384 Well Plate Capability The Equalizer ... original Equalizerexpandable and equal tip spacing, choice of ... capabilities. In addition, this model allows you to ... loading and accessing many gels and for use ...
Medicine Products: