Navigation Links
Zinc's role in the brain
Date:10/5/2011

Zinc plays a critical role in regulating how neurons communicate with one another, and could affect how memories form and how we learn. The new research, in the current issue of Neuron, was authored by Xiao-an Zhang, now a chemistry professor at the University of Toronto Scarborough (UTSC), and colleagues at MIT and Duke University.

Researchers have been trying to pin down the role of zinc in the brain for more than fifty years, ever since scientists found high concentrations of the chemical in synaptic vesicles, a portion of the neuron that stores neurotransmitters. But it was hard to determine just what zinc's function was.

In the new work, the researchers designed a chemical called ZX1 that would bind with zinc rapidly after it was released from the vesicles but before it could complete its journey across the synapse. Using the chemical, they were able to observe how neurons behaved when deprived of zinc.

"As a chemist, I'm proud that I can make a contribution to neuroscience," says Zhang, who helped design the chemical while conducting postdoctoral research in Stephen J. Lippard's lab at MIT. He was joint first author of the paper, along with Enhui Pan from James O. McNamara's group at Duke University.

The researchers studied neurons in a brain region called the hippocampus, which is associated with learning and memory formation. They found that removing zinc interfered with a process called long-term potentiation . Long-term potentiation strengthens the connection between two neurons, and seems to be important for memory and learning.

Zhang is currently working on developing new contrast agents that could be used in medical imaging.


'/>"/>

Contact: Xiao-an Zhang
xazhang@utsc.utoronto.ca
416-287-7202
University of Toronto Scarborough
Source:Eurekalert

Page: 1

Related medicine news :

1. Gadgets not related to teenagers brain pain
2. Dementia Rates Escalate as Brain Capacity Diminishes with Age
3. Researchers discover new way to kill pediatric brain tumors
4. Scientists Pinpoint Area of Brain That Fears Losing Money
5. Physical Changes in Brain Linked to Altered Spirituality
6. Pro Athletes Brains React at Olympic Speed
7. Neuroscientists reveal new links that regulate brain electrical activity
8. Brain Scan Shows What Beauty is Worth
9. Study supports alternative anti-seizure medication following acute brain injury
10. Exercise helps protect brain of multiple sclerosis patients
11. Pittsburgh Neurosurgeons Explore Use of Drug that Illuminates Brain Tumor Cells To Guide Surgery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many kids ... sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids excited ... all ages; it is a non-competitive, non-timed event, which is all about having fun ...
(Date:10/13/2017)... ... 13, 2017 , ... Coveros, a leader in agile coaching ... contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise Agile ... of Agile methodologies in a consistent and high value manner across CMS programs. ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare ... program management, will showcase a range of technology and learning solutions at the ... Convention and Expo to be held October 14–18, 2017 at the Mandalay Bay ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... the demand of today’s consumer and regulatory authorities worldwide. From Children’s to Adults ... tested to meet the highest standard. , These products are also: Gluten ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... in post-acute health care, have expanded their existing home health joint venture through ... AccentCare has been operating a joint venture home health company with Asante, delivering ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... --  Divoti USA will engrave and process all ... the latest FDA requirements, which stipulates new criteria regarding medical device ... of Medical ID jewelry such as Medical ID Bracelets, can rest ... terms of the new FDA requirements . ... Divoti offers this dark mark fiber laser engraving ...
(Date:10/11/2017)... , Oct. 11, 2017  Caris Life Sciences ® ... fulfilling the promise of precision medicine, today announced that ... Caris, Precision Oncology Alliance™ (POA) as its 17 th ... the St. Jude Crosson Cancer Institute will help develop ... use of tumor profiling, making cancer treatment more precise ...
(Date:10/10/2017)... 10, 2017  NDS received FDA 510(k) clearance in May 2017 ... display stand specifically designed for endoscopy environments. An innovative secondary monitor ... clinical solution to support the improvement of patient outcomes, procedural efficiency, ... ... ...
Breaking Medicine Technology: