Navigation Links
Zinc May Counter Effects of Alcohol in Early Pregnancy
Date:2/5/2009

But findings don't mean it's safe for expectant moms to drink, study says

THURSDAY, Feb. 5 (HealthDay News) -- Zinc supplements may help mothers-to-be reduce the risk for birth defects linked to alcohol use early in pregnancy, Australian researchers report.

The study, conducted in mice, was published online and in the April print issue of the journal Alcoholism: Clinical & Experimental Research.

"Alcohol's damage to the fetus depends not only on the amount and duration of alcohol exposure, but also on the timing of the exposure relative to the development of the cells and tissues involved," study co-author Peter Coyle, an associate professor at the Hanson Institute in Adelaide, said in a journal news release.

"Earlier work had shown that prenatal alcohol, as well as other toxins, can result in fetal zinc deficiency and (developmental malformations) by inducing the zinc-binding protein, metallothionein, in the mother's liver. Since then, our group has confirmed the importance of metallothionein in alcohol-mediated birth defects," he said.

In this study, Coyle and colleagues injected either saline or a 25 percent solution of alcohol into pregnant mice on their eighth day of gestation. In mice, the eighth day of gestation is equivalent to weeks three to eight during a human pregnancy. The mice were fed either a regular or zinc-supplemented diet from conception to day 18 of gestation, when some fetuses were assessed for birth defects. The growth of the surviving offspring was monitored for 60 days after birth.

"There were three key findings," Coyle said.

"One, fetal abnormalities caused by acute alcohol exposure in early pregnancy can be prevented by dietary zinc supplementation. Two, dietary zinc supplementation throughout pregnancy can protect against post-natal death caused by acute alcohol exposure in early pregnancy. Three, dietary zinc supplementation increases the mother's blood zinc to overwhelm the transient drop in zinc caused by alcohol, which we believe prevents the fetal zinc deficiency and subsequent fetal damage."

These findings don't mean that taking zinc makes it safe for women to drink during pregnancy, however.

"We have not determined whether zinc protects against all of the possible negative outcomes from alcohol exposure in pregnancy," Coyle said. "Nor would we recommend that makers of alcoholic beverages include zinc in their product so that women can drink while pregnant. Indeed, we take the conservative stand of a 'no alcohol policy' during pregnancy. What our studies do indicate is that dietary zinc supplementation could be as important as folic acid and applied as a simple prophylactic treatment in the human setting to prevent the effects of a range of insults in pregnancy."

More information

The U.S. National Institute of Alcohol Abuse and Alcoholism has more about drinking during pregnancy.



-- Robert Preidt



SOURCE: Alcoholism: Clinical & Experimental Research, news release, Feb. 2, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. USP announces new standards to protect patients from counterfeit and adulterated medicines
2. Brez(R), the First Over-the-Counter, Intranasal Breathing Aid Clinically Proven to Reduce Primary Snoring, Debuts in Rite Aid Pharmacies
3. First-Ever Over-the-Counter Dual Action Iron Supplement Available at Major Retail Outlets in the United States; Bifera is a New, Innovative Dual Iron Supplement Now on the Market
4. Teleconference on Monday, January 19, Announcing New, Innovative Dual Iron Supplement Now Available Over the Counter
5. Lumension Security's Audiocast Focuses on Evolving Threats and Countermeasures: Achilles Heel of Data Loss and Theft
6. Cardiac stent patients with diabetes may benefit from drug that counteracts the effects of leptin
7. The ASCII Group Partners with Association Health Programs to Counter Rising Health Insurance Costs
8. Greenland's National Management of Health Partners with AMD Global Telemedicine Inc. and AFHCAN to Install Telemedicine Encounter Management Systems (TEMS) Across Greenland
9. Generic Heart Drugs as Good as Brand-Name Counterparts
10. Partnership for Safe Medicines Arms Public Against Counterfeit Drugs
11. Draeger Counters What It Believes Are Unsubstantiated Allegations of Patent Infringement by Sperian
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Zinc May Counter Effects of Alcohol in Early Pregnancy
(Date:5/26/2016)... ... ... Connor Sports, through its Connor Cares initiative, will continue to expand ... Tour that will commemorate the Indiana Fever legend’s hall-of-fame career and final WNBA ... levels of the game, Connor Sports has committed to a significantly increased focus on ...
(Date:5/26/2016)... ... May 26, 2016 , ... Cardiac arrhythmia is ... impact on long-term patient survival, reports a team of UPMC researchers in the ... in the Journal of Thoracic and Cardiovascular Surgery, provide critical information that will ...
(Date:5/26/2016)... ... May 26, 2016 , ... Catalent ... for drugs, biologics, consumer health and global clinical supply services, today announced two ... support the company’s continued investment and strategic growth plans in the Asia Pacific ...
(Date:5/26/2016)... ... ... to provide hair restoration information to the widest possible audience, Dr. Parsa Mohebi is making ... app. Dr. Mohebi, the founder of Parsa Mohebi Hair Restoration, is making all of his ... says, “The positive response to the Snapchat videos we started last month has been overwhelming. ...
(Date:5/26/2016)... ... May 26, 2016 , ... Eating Recovery Center, Washington ... opening a brand new child and adolescent residential treatment center on June 1. ... even more specialized eating disorder treatment and access to life-saving care. , To ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... GERMANTOWN, Maryland , May 25, ... Therawis bedient dringenden Bedarf ... QIAGEN N.V. (NASDAQ: QGEN ; ... Lizenz- und Entwicklungsvereinbarung mit Therawis Diagnostics GmbH zur ... eingegangen zu sein. Ein erstes Projekt wird die ...
(Date:5/25/2016)... Florida , May 25, 2016 ... Conference & Expo earlier this month, the numbers and ... revenues continue to climb into the billions, more research ... newly released 4th Edition State of Legal Marijuana Markets ... a cannabis-focused data-analysis firm, much of the increase in ...
(Date:5/25/2016)... 2016 ReportsnReports.com adds "Chronic ... that provides an overview on therapeutic pipeline of ... stages, therapeutics assessment by drug target, mechanism of ... type, along with latest updates, and featured news ... involved in the therapeutic development for Chronic Cough ...
Breaking Medicine Technology: