Navigation Links
Zinc May Counter Effects of Alcohol in Early Pregnancy
Date:2/5/2009

But findings don't mean it's safe for expectant moms to drink, study says

THURSDAY, Feb. 5 (HealthDay News) -- Zinc supplements may help mothers-to-be reduce the risk for birth defects linked to alcohol use early in pregnancy, Australian researchers report.

The study, conducted in mice, was published online and in the April print issue of the journal Alcoholism: Clinical & Experimental Research.

"Alcohol's damage to the fetus depends not only on the amount and duration of alcohol exposure, but also on the timing of the exposure relative to the development of the cells and tissues involved," study co-author Peter Coyle, an associate professor at the Hanson Institute in Adelaide, said in a journal news release.

"Earlier work had shown that prenatal alcohol, as well as other toxins, can result in fetal zinc deficiency and (developmental malformations) by inducing the zinc-binding protein, metallothionein, in the mother's liver. Since then, our group has confirmed the importance of metallothionein in alcohol-mediated birth defects," he said.

In this study, Coyle and colleagues injected either saline or a 25 percent solution of alcohol into pregnant mice on their eighth day of gestation. In mice, the eighth day of gestation is equivalent to weeks three to eight during a human pregnancy. The mice were fed either a regular or zinc-supplemented diet from conception to day 18 of gestation, when some fetuses were assessed for birth defects. The growth of the surviving offspring was monitored for 60 days after birth.

"There were three key findings," Coyle said.

"One, fetal abnormalities caused by acute alcohol exposure in early pregnancy can be prevented by dietary zinc supplementation. Two, dietary zinc supplementation throughout pregnancy can protect against post-natal death caused by acute alcohol exposure in early pregnancy. Three, dietary zinc supplementation increases the mother's blood zinc to overwhelm the transient drop in zinc caused by alcohol, which we believe prevents the fetal zinc deficiency and subsequent fetal damage."

These findings don't mean that taking zinc makes it safe for women to drink during pregnancy, however.

"We have not determined whether zinc protects against all of the possible negative outcomes from alcohol exposure in pregnancy," Coyle said. "Nor would we recommend that makers of alcoholic beverages include zinc in their product so that women can drink while pregnant. Indeed, we take the conservative stand of a 'no alcohol policy' during pregnancy. What our studies do indicate is that dietary zinc supplementation could be as important as folic acid and applied as a simple prophylactic treatment in the human setting to prevent the effects of a range of insults in pregnancy."

More information

The U.S. National Institute of Alcohol Abuse and Alcoholism has more about drinking during pregnancy.



-- Robert Preidt



SOURCE: Alcoholism: Clinical & Experimental Research, news release, Feb. 2, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. USP announces new standards to protect patients from counterfeit and adulterated medicines
2. Brez(R), the First Over-the-Counter, Intranasal Breathing Aid Clinically Proven to Reduce Primary Snoring, Debuts in Rite Aid Pharmacies
3. First-Ever Over-the-Counter Dual Action Iron Supplement Available at Major Retail Outlets in the United States; Bifera is a New, Innovative Dual Iron Supplement Now on the Market
4. Teleconference on Monday, January 19, Announcing New, Innovative Dual Iron Supplement Now Available Over the Counter
5. Lumension Security's Audiocast Focuses on Evolving Threats and Countermeasures: Achilles Heel of Data Loss and Theft
6. Cardiac stent patients with diabetes may benefit from drug that counteracts the effects of leptin
7. The ASCII Group Partners with Association Health Programs to Counter Rising Health Insurance Costs
8. Greenland's National Management of Health Partners with AMD Global Telemedicine Inc. and AFHCAN to Install Telemedicine Encounter Management Systems (TEMS) Across Greenland
9. Generic Heart Drugs as Good as Brand-Name Counterparts
10. Partnership for Safe Medicines Arms Public Against Counterfeit Drugs
11. Draeger Counters What It Believes Are Unsubstantiated Allegations of Patent Infringement by Sperian
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Zinc May Counter Effects of Alcohol in Early Pregnancy
(Date:5/24/2017)... Hills, CA (PRWEB) , ... May 24, 2017 , ... ... announced today its participation in nVerge 2017 – a one-day technology conference in San ... Altec’s document management solution, which allows users to fully utilize and enhance their Sage ...
(Date:5/24/2017)... Cincinnati, OH (PRWEB) , ... May 24, 2017 , ... ... discreet and comfortable ClearCorrect orthodontics, with or without a referral. Dr. Kejriwal ... is why she offers convenient, clear braces in Cincinnati, OH. Patients no longer need ...
(Date:5/24/2017)... ... ... Myers Jackson is well known for auctioning homes that people move and flip. ... planet. The luxury home market is alive and well and there are mansions for ... “11 Spyglass Hill Auction will enlighten you on the dynamics of how to market ...
(Date:5/24/2017)... ... May 24, 2017 , ... Medic CE , ... Surprising Truth about Pediatric Septic Shock” hosted by the Journal of Emergency Medical Services ... p.m. Eastern time, will be presented by Captain Rommie Duckworth, LP, a career fire ...
(Date:5/24/2017)... Massapequa Park, NY (PRWEB) , ... May 24, ... ... today announced the practice is offering holistic pediatric dentistry options for its patients ... the context of the patient’s entire physical well being, and is one of ...
Breaking Medicine News(10 mins):
(Date:5/4/2017)... --  BioLife Solutions , Inc. (NASDAQ: BLFS ... clinical grade hypothermic storage and cryopreservation ... that the Company,s first quarter 2017 financial results will ... 2017, and that the Company will host a conference ... afternoon. Management will provide an overview of the Company,s ...
(Date:5/3/2017)... , May 3, 2017  Getinge, a ... contribute to quality enhancement and cost efficiency within ... a study of contemporary practice demonstrating that intra-aortic ... therapy for critically ill patients. The single-center, retrospective, ... newer large volume MEGA ® 50cc intra-aortic ...
(Date:5/2/2017)...  George Clinical, a leading full-service CRO in the ... Oncology, a Memphis -based leader ... that George Clinical has acquired Vector Oncology,s Pharma Services (CRO) ... purpose of strengthening the ability of George Clinical ... throughout the Asia-Pacific , the ...
Breaking Medicine Technology: