Navigation Links
Zebrafish popular with researchers
Date:1/26/2011

TORONTO, Ont.-- Zebrafish are the new fruit flies.

And it's not just because they breed like rabbits.

Generations of high school students learned about genetics and developmental biology by breeding and studying fruit flies (Drosophila melanogaster).

Fruit flies were also one of the most important research animals because they reproduce quickly and, well, fruitfully; they don't require much love and attention; and they share many genes and proteins with humans.

Now there's a new kid in town: The zebrafish is becoming increasingly popular among researchers, such as Dr. Xiao-Yan Wen.

Wen already has more than 1,000 zebrafish in his state-of-the-art lab where he and others perform chemical genetic screens in which chemicals or drugs from a large library of compounds are tested for their effects on early zebrafish development. Because the tests are carried out on a complete, developing organisma vertebrate in this case--researchers get more detailed and complex information about the impact of the chemical than if they were testing them on cell cultures.

Wen is director of St. Michael's Zebrafish Facility and its Zebrafish Centre for Advanced Drug Discovery.

Zebrafish produce lots of eggs a healthy mating pair can produce 100 to 200 a week. Fertilization and development occur externally, so researchers can directly observe and manipulate the embryoes. Plus, they are transparent, so researchers can see what's going on, or inject them with fluorescent dye.

Wen's primary focus has been cardiovascular disease, the country's top public health threat. Wen's team has already identified one drug, rosuvastatina cholesterol-lowering statin sold as Crestor by AstraZenecathat suppressed the growth of transplanted human prostate cancer cells in mice. That research appeared in the September 2010 issue of the journal European Urology.

However, this screening process is labor-intensive. It takes one e
'/>"/>

Contact: Leslie Shepherd
shepherdl@smh.ca
416-864-6094
St. Michael's Hospital
Source:Eurekalert

0

GOOD

Page: 1 2

Related medicine news :

1. EMBL picture release: Developing zebrafish patchwork
2. Tanning Beds Still Popular Despite Skin Cancer Risk
3. Popular Mechanics breakthrough awardees announced
4. Popular prostate cancer treatment associated with bone decay
5. New guideline finds no evidence for a popular back procedure
6. Expert Panel Links Popular Bone Drugs to Rare Fracture
7. Popular diabetes drugs associated with fractures in type 2 diabetic patients
8. New research finds no evidence that popular slimming supplements facilitate weight loss
9. Iceland -- Working on its Popularity for Travellers, Iceland ProTravel Supports Ad Campaign "Inspired by Iceland"
10. SDI Reports: Roughly Half of Patients Prescribed the Most Popular Osteoporosis Drugs Discontinue Therapy Within 6 Months -- Amgen's Prolia Offers New Dosing Option
11. New iPhone App “Wing Chun Masters” Brings 400-Year-Old Kung Fu To Life Amidst Renewed Popular Interest In Culture.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... City, UT (PRWEB) May 23, 2013 ... , a comprehensive radiology learning environment for all ... prebuilt lessons and assessments, transforms the learning experience ... radiology curriculum. , “Until RADPrimer 3.0, ... second to none,” comments Dr. B.J. Manaster, Professor ...
(Date:5/23/2013)... THURSDAY, May 23 (HealthDay News) -- A modified ... help fight brain tumors, preliminary research suggests. ... investigational therapy, known as PVSRIPO, uses an engineered ... normal cells, but attacks cancer cells. The therapy ... most common and aggressive brain tumor, they said. ...
(Date:5/23/2013)... Memorial Day Focus Spotlight on Military ... a part of the U.S. Military for more than ... it, these men and women will be honored for ... America. As veterans transition to civilian life, there ... workplace chaplaincy world. , Marketplace Chaplains, America’s original ...
(Date:5/23/2013)... a year ago, the leading journal Science ... drug. A significant breakthrough and an important starting point ... De Strooper Alzheimer,s researcher at VIB and KU ... D,Hooge KU Leuven and scientists at Janssen ... Alzheimer,s animal test models. Their results were different, as ...
(Date:5/23/2013)... (PRWEB) May 23, 2013 Susquehanna ... Site, offering a comprehensive babysitting training course for adolescents ... was developed by Indianapolis pediatrician Dr. Patricia Keener after ... care of an adult sitter who didn’t know how ... youth development program with a medical basis that aims ...
Breaking Medicine News(10 mins):Health News:RADPrimer 3.0 Introduces Comprehensive Radiology Training Curriculum 2Health News:Modified Polio Virus May Help Fight Brain Tumors, Study Suggests 2Health News:Memorial Day Focus Spotlight on Military Chaplains Transitioning in the Marketplace 2Health News:Memorial Day Focus Spotlight on Military Chaplains Transitioning in the Marketplace 3Health News:New insights contradict promising Alzheimer's research 2Health News:Susquehanna Health Offers Safe Sitter Course for Tweens and Teens 2Health News:Susquehanna Health Offers Safe Sitter Course for Tweens and Teens 3
... be a sensitive screening tool for the detection of ... young women can complicate mammographic interpretation. ,As ... detection of breast cancer is high and virtually uncompromised ... using breast MRI as a screening tool. ...
... Thailand who was infected by H5N1 bird flu virus and managed ... years old Pranom Thongchan, of Srisomboon, central Thailand, tells her horrific ... was her niece who coughed blood as she passed away in ... attacked her sister, the girl's mother, and she was dead. After ...
... of Chain Restaurants (council representing McDonald's, Burger King, KFC and ... before the senate. //The case in which the opponents wanted ... food. The lawmakers voted 306-120 in favor of the Personal ... to put case on food industry for causing overweight. ...
... has greatly improved over the few years and continues to ... achievement where a premature baby of less than 26 weeks ... be the third case of saving such babies. ,A ... a week. If the baby is delivered before full-term pregnancy, ...
... Carotenoids are being hailed as extremely important nutritionally ... Agricultural Research Service (ARS) scientists has revealed new ... body.// ,Using isotopes to tag carotenoids from ... Nutrition Research Center (BHNRC) monitored the nutrients' absorption ...
... one of the top organ transplant hospitals in California ... national improperly received an organ ahead of dozens of ... Times reported that officials at St. Vincent Medical Center ... allegedly falsified records of the operation on numerous occasions, ...
Cached Medicine News:Health News:MRI as a diagnostic tool for breast cancer 2Health News:Bird Flu Survivor Recounts her ‘hell 2Health News:India’s smallest premature baby brings immense joy to Indian parent 2Health News:Carotenoid Absorption Explained In A Better Manner 2
(Date:5/23/2013)... JERUSALEM , May 23, 2013  Hadasit Bio-Holdings ... portfolio of biotech companies, based on intellectual property ... Israel ,s foremost medical research center, ... Neurosciences Ltd., received significant funding from the Israeli ... Chief Scientist (OCS) to support product development and ...
(Date:5/23/2013)... 23, 2013  Texas, premier physician associations today announced ... survival tools they need to provide demonstrably better and ... care marketplace. "I am confident the Physician ... said Stephen L. Brotherton , MD, ... Texas doctors are determined to make health ...
(Date:5/23/2013)... 2013  Net Medical Xpress Solutions, Inc., (OTC QB: ... the company has signed a letter of intent to ... Huntsville, AL . MedTel Solutions is ... and recruitment of telemedicine physicians. Consideration for the acquisition ... which is expected by June 30, 2013. ...
Breaking Medicine Technology:Hadasit Bio-Holdings Ltd. Portfolio Company - Cell Cure Neurosciences Ltd. Received Additional Government Support 2TMA Launches Physician Services Organization for Patient Care 2TMA Launches Physician Services Organization for Patient Care 3TMA Launches Physician Services Organization for Patient Care 4Net Medical Xpress Announces Acquisition of Telemedicine Staffing Company 2Net Medical Xpress Announces Acquisition of Telemedicine Staffing Company 3
... OXYPLETH is seven pounds of intelligent ... combined with software developed over 7 ... provides the ultimate in non-invasive oxygen ... oximeter monitor technology and sophisticated saturation ...
... The Models 512 and 513 ... processing. This advanced technology is able ... higher resolutions and speeds of 100 ... results in improved pulse oximeter performance ...
CO 2 SMO-Capnograph/Pulse Oximeter...
... and 513 handheld pulse oximeters incorporate ... is able to process pulsatile signals ... of 100 times per second. This ... oximeter performance during motion or low ...
Medicine Products: