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Yves Pichon’s New Book Presents Latest Neurophysiological Discoveries
Date:5/23/2013

UNITED KINGDOM (PRWEB) May 24, 2013

The sodium theory has been elegantly proposed by A.L. Hodkin, A.F. Huxley and B. Katz in the early 1950s, after their experiments on Plymouth squids, to account for the role of sodium and potassium ions in nerve functions. Since then, the electrophysiological techniques and the data acquisition techniques have known amazing developments. In The Sodium Theory Revisited, author Yves Pichon wants to give an account of the latest developments in the field since then in different laboratories experimenting with a variety invertebrate species.

One of the most important technical developments has been the use of single cockroach axons, which have been found to behave very much like squid axons. Another almost simultaneous development, which proved extremely useful for the understanding of the nerve function, was “in situ” microelectrode recording, enabling an indirect analysis of the extra-axonal environments. Experiments on several species indicate that the CNS is protected from the ionic environment by the blood-brain barrier. On the other hand, quite unexpectedly, little ion accumulation is detected in the vicinity of the axonal membrane in various physiological conditions. Another innovating technique was the 'patch-clamp' technique which enables the recording of the activity of individual ionic channels in cultured neu
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