Navigation Links
Younger men with advanced prostate cancer have shorter survival times
Date:5/21/2009

While young men with prostate cancer have a low risk of dying early, those with advanced forms of cancer do not live as long as older men with similar forms of the disease. That is the conclusion of a new study published in the July 1, 2009 issue of CANCER, a peer-reviewed journal of the American Cancer Society. The paradoxical findings indicate that there may be biological differences between prostate cancers that develop in younger men and those that develop in older men, and that uncovering these differences may help tailor screening and treatment strategies for patients based on age.

In general, a younger cancer patient has a better prognosis than an older patient with the same type of cancer. Few studies have analyzed the health of younger vs. older men after diagnosis and treatment for prostate cancer, though.

To investigate the impact of age on prostate cancer prognosis, Daniel Lin, M.D., of the University of Washington and colleagues designed a study to examine the association between age at diagnosis and health outcomes in men diagnosed with prostate cancer in the United States. Mining the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) database, the investigators identified 318,774 men diagnosed with prostate cancer between 1988 and 2003. Men aged 35 to 74 years were stratified by age at the time of diagnosis, and the researchers examined differences in tumor characteristics, treatment, and survival within each age group.

The analysis revealed that, over time, men are being diagnosed with prostate cancer at younger ages, likely due to more extensive screening. Also, younger men are more likely to be treated with prostatectomy, have less aggressive cancers, and have a better chance of survival after 10 years compared with older men. However, among men with advanced prostate cancers, the youngest men (aged 35 to 44 years) have a particularly poor prognosis compared with older men. These young men are more likely to die from cancer or another cause sooner than older men with similar forms of cancer.

While the reasons for this unexpected finding are not clear, the researchers suspect that young men with advanced prostate cancer may have biologically more aggressive forms of the disease than the forms that are diagnosed in older men. Additional studies are needed to determine what, if any, underlying differences exist between advanced prostate cancer found in young men vs. those found in older men. These studies may help clinicians improve screening in young men and could ultimately lead to the development of better treatment strategies for these patients.


'/>"/>

Contact: David Sampson
david.sampson@caner.org
American Cancer Society
Source:Eurekalert

Related medicine news :

1. New Longevinex Advantage(R) Designed for Americans Who Want to Live Longer and Look Younger
2. Surgery improves survival for prostate cancer patients younger than 50
3. Younger Age of More Severe Swine Flu Cases Worries Experts
4. Younger Age of Severe Swine Flu Cases Worries Experts
5. Transplanted liver cells function in older animals but do not proliferate as much as in younger ones
6. Gene Test May ID Younger Women at Risk for Melanoma
7. NYU study finds new risk factor for melanoma in younger women
8. Band Aid Mini Facelift Developed by Atlanta Plastic Surgeon John L. LeRoy, MD can Help Patients Look Younger for Less Money
9. Younger Women With Breast Cancer Face Added Peril
10. Older Adults Get Drunk Faster Than Younger Drinkers
11. Younger breast cancer patients have greater chance of recurrence
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2017)... ... April 24, 2017 , ... Miami ... attending the 2017 Oral Reconstruction Foundation’s 2017 Symposium on Tissue Regeneration and Implant ... will present its annual Global Symposium at the Fontainebleau Hotel located in Miami ...
(Date:4/24/2017)... ... April 24, 2017 , ... Anaconda BioMed, ... neuro-thrombectomy systems for the treatment of Acute Ischemic Stroke (AIS), today announced it ... as the product advances towards regulatory and clinical phases. , "This is another ...
(Date:4/23/2017)... ... April 23, 2017 , ... Altura ... the achievement of Cisco Select certification and SMB specialization. Altura is now ... , In earning the Select Certification, Altura fulfilled the training and exam ...
(Date:4/22/2017)... ... April 22, 2017 , ... PharmacyChecker.com released its first ... average of 70% when buying medication online from Canadian pharmacies verified in the ... from other countries. The report (chart below) compares U.S. and foreign prices for ...
(Date:4/21/2017)... ... April 21, 2017 , ... An April 10 article in the ... which reveal a great deal about prehistoric ice-age dental practitioners and their primitive and, ... used to remove decayed dental matter, and that teeth were then filled with bitumen, ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... Inc ., a digital health company focused on modernizing and ... $25 million in Series B funding led by Qiming US ... Seattle that is part of a broader family ... included participation from SR One , who led ZappRx,s ... Google Ventures). As part of the financing, Mark McDade ...
(Date:4/20/2017)... Research and Markets has announced the ... Application Analysis, Regional Outlook, Growth Trends, Key Players, Competitive Strategies ... ... was valued at US$ 7,167.6 Mn in 2015, and is ... a CAGR of 5.6% from 2016 to 2024. ...
(Date:4/20/2017)... 20, 2017 NeuroVive Pharmaceutical AB (Nasdaq ... positive preclinical results demonstrating anti-fibrotic effects with ... steatohepatitis (NASH), in an additional well-validated experimental ... has previously shown similar anti-fibrotic effects in ... scientists present novel data demonstrating anti-fibrotic effects ...
Breaking Medicine Technology: