Navigation Links
Young patients with metastatic colorectal cancer are at high risk of disease progression and death
Date:9/27/2013

Younger patients with colorectal cancer that has spread (metastasised) to other parts of the body represent a high-risk group that is less likely to respond to anti-cancer treatments. Their disease is more likely to progress and they are at greater risk of death than other age groups, according to new research to be presented to the 2013 European Cancer Congress (ECC2013) [1] today (Sunday).

An analysis of 20,034 patients in 24 phase III clinical trials [2] for colorectal cancer, of which 695 patients (3%) were younger than 40, showed that the youngest and oldest patients had the highest risk of their disease progressing and of dying, compared to middle-aged patients. When compared to 57-year-olds, the youngest patients had a 30% increased risk of dying from the disease, and, when compared to 61-year-olds, they had a 28% increased risk of their disease progressing and metastasising during the first year of follow-up after randomisation and the start of treatment. The oldest patients had a 72% increased risk of death and a 19% increased risk of their disease metastasising compared to the 57 and 61-year-olds during the follow-up period.

Dr Christopher Lieu, MD, an assistant professor at the University of Colorado (USA), will tell the congress: "Although colorectal cancer occurs in only 4.6% of patients who are younger than 50, the incidence of the disease has been increasing at a rate of 1.5% per year from 1992 to 2005 in this age group. The most dramatic increases have been observed in the 20-29 year-old group, where there has been an annual 5.2% increase in cases in men and a 5.6% increase in women, and in the 30-39 year-old group, where there has been an annual 3% increase in men and a 2% increase in women. [3]

"The reasons why the incidence is increasing in younger patients remain unknown, although genetic predisposition, environmental factors, fewer early cancer detections in this population, or a combination of these factors are
'/>"/>

Contact: José Abad
ecco2013press@gmail.com
ECCO-the European CanCer Organisation
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. HPV Linked to Growing Number of Young Adults with Oropharyngeal Cancer
2. HPV linked to growing number of young adults with oropharyngeal cancer
3. Adult cancer patients younger than 50 with limited brain mets have improved OS after SRS alone
4. BloomingKids Releases Android Apps for Teaching Autistic, Young, and Learning-Disabled Kids
5. Comprehensive Arthroscopic Management - CAM Procedure - Successfully Delays Shoulder Replacement for Young, Active Patients with Shoulder Osteoarthritis
6. Federal Grant of $275,000 Funds Study of Young Adult Attitudes Toward Flavored Tobacco
7. Federal grant of $275,000 funds study of young adult attitudes toward flavored tobacco
8. Why do young adults start smoking?
9. Hawkins Parnell Thacktson & Young LLP Elects Five New Partners
10. Researcher gets National Science Foundations most prestigious award for young faculty
11. New Study Highlights Young People As a Philanthropic Force
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... (PRWEB) September 18, 2014 Memorial ... made history this week by performing the first ever, ... UNOS (United Network for Organ Sharing) approval to launch ... one of only two programs in South Florida. ... Dr. Enrique Gongora, Medical Director of the ...
(Date:9/18/2014)... -- Older people become more physically vulnerable during bereavement, ... stress hormones during bereavement changes with age, British researchers ... are more likely to have weakened immune systems and ... weeks and months after loss, we can suffer from ... of white blood cell and as such are essential ...
(Date:9/18/2014)... One of the most capable and ... ShandsCair Flight Program’s new EC155 B1, will ... at the Air Medical Transport Conference (AMTC), Sept. 22-24, ... into service ShandsCair EC155 and the Vanderbilt University ... AMTC highlight Airbus Helicopters broad, industry leading line-up of ...
(Date:9/18/2014)... -- Daily supplements of selenium or vitamin E don,t ... cataracts among men, a new study indicates. Previous ... help prevent cataracts. To investigate this further, William Christen, ... in Boston, and his colleagues examined data from a ... trial was initially designed to study prevention of prostate ...
(Date:9/18/2014)... Thousands of college and high school ... fundraising impact on 127 member Children’s Miracle Network ... Dance Marathon Day will officially kick off a school ... raised by college and high school students funding vital ... Dance Marathon campus programs help provide medical equipment, treatment ...
Breaking Medicine News(10 mins):Health News:Memorial Cardiac & Vascular Institute Performs First Adult Heart Transplant in Broward County 2Health News:Memorial Cardiac & Vascular Institute Performs First Adult Heart Transplant in Broward County 3Health News:Memorial Cardiac & Vascular Institute Performs First Adult Heart Transplant in Broward County 4Health News:Grief Can Weigh on Immune System in Older Folks, Study Says 2Health News:Airbus Helicopters Inc. Features Industry-leading Models at AMTC 2Health News:Airbus Helicopters Inc. Features Industry-leading Models at AMTC 3Health News:Airbus Helicopters Inc. Features Industry-leading Models at AMTC 4Health News:Vitamin E, Selenium Supplements Don't Seem to Prevent Cataracts 2Health News:250 Campuses Usher in School Year of Saving Kids’ Lives During First-Ever “Dance Marathon Day” on Sept. 25 2
... ... Locally, , ... WA (PRWEB) July 2, 2010 -- Bill the Butcher Inc. opened a neighborhood butcher ... executive officer., , ,Located at 3800 34th Ave West in Seattle,s Magnolia neighborhood, the ...
... patients with Hodgkin lymphoma (HL) and a history of heart ... after completing treatment, according to research published online today in ... Hematology. HL is a form of cancer of arising in ... the disease in 2009, according to the American Cancer Society. ...
... at Karolinska Institutet recommends a new routine for protection ... for feeding directly through the abdominal wall, is surgically ... simpler and cheaper than the one used today. The ... has been clinically tested on over 200 patients at ...
... Register now for ... of women, at the Mariandale Retreat Center -- right outside of NYC, which will be held ... workshops, room and board, is only $350 until July 9, 2010. , ... New York, NY (PRWEB) July 2, 2010 -- Need to get ...
... ... is pleased to announce the Grand Opening of their newly expanded pain treatment center in ... ... are located at 638 West Duarte Road, Suite 18, Arcadia, California 91007. The Los Angeles ...
... ... , ... 1, 2010-- Aromatherapy isn’t new to the field of natural health. Ancient Egyptians were the ... the Romans to modern day, essential oils have been part of a holistic approach to ...
Cached Medicine News:Health News:In Time for July 4th Grilling, Bill the Butcher Opens 5th Butcher Shop 2Health News:Lymphoma patients with cardiovascular disease have increased risk of cardiac hospitalization 2Health News:Simpler and cheaper antibiotic prophylaxis with insertion of nutrition catheter in the stomach 2Health News:Relax, Release and Rejuvenate at Upcoming Women's Retreat 2Health News:Relax, Release and Rejuvenate at Upcoming Women's Retreat 3Health News:Advanced Pain Institute Opens Expanded Los Angeles Area Pain Management Center 2Health News:Certified Organic Aromatherapy Oils Available from Swanson Health Products 2
(Date:9/18/2014)... BURLINGTON, Mass. , Sept. 18, 2014 /PRNewswire/ ... post-launch in the United States ... have prescribed GlaxoSmithKline,s BRAF inhibitor Tafinlar for ... 49 percent who have prescribed GlaxoSmithKline,s MEK inhibitor ... the highest percentage (42 percent and 43 percent, ...
(Date:9/18/2014)... 18, 2014  Iliad Neurosciences, Inc., a company focused ... treating Autism Spectrum Disorders (ASD) announced today that it ... Research Foundation for The State University of New York. ... new biomarker to identify an abnormality in folate transport ... biomarker is expected to be available for research use ...
(Date:9/18/2014)... BURLINGTON, Mass. , Sept. 18, 2014  Decision ... launched anti-vascular endothelial growth factor (VEGF) agent for wet ... and Medicare Advantage plans as Genentech,s Lucentis, which is ... although surveyed managed care organization (MCO) directors do not ... Eylea is slightly more likely than Lucentis to be ...
Breaking Medicine Technology:At One Year Post-Launch, Approximately One Half of Surveyed U.S. Medical Oncologists Have Prescribed Single-Agent Tafinlar and Mekinist to Their Malignant Melanoma Patients 2Iliad Neurosciences, Inc. enters into an Exclusive License Agreement with The Research Foundation for The State University of New York 2Iliad Neurosciences, Inc. enters into an Exclusive License Agreement with The Research Foundation for The State University of New York 3Regeneron's Eylea and Genentech's Lucentis Are Equally Likely to be Covered on Commercial and Medicare Advantage Plans for Wet AMD 2Regeneron's Eylea and Genentech's Lucentis Are Equally Likely to be Covered on Commercial and Medicare Advantage Plans for Wet AMD 3
... An APTT-based kit for the screening of ... specificity of the test for the factor ... sample plasma with an excess of V-DEF ... possible to discriminate between heterozygous and homozygous ...
Inquire...
Inquire...
... remarkable anti-reflux valve is enclosed ... which prevents the valve from ... in sitting or reclining positions. ... and interference free ensuring uninterrupted ...
Medicine Products: