Navigation Links
Young patients with metastatic colorectal cancer are at high risk of disease progression and death
Date:9/27/2013

Younger patients with colorectal cancer that has spread (metastasised) to other parts of the body represent a high-risk group that is less likely to respond to anti-cancer treatments. Their disease is more likely to progress and they are at greater risk of death than other age groups, according to new research to be presented to the 2013 European Cancer Congress (ECC2013) [1] today (Sunday).

An analysis of 20,034 patients in 24 phase III clinical trials [2] for colorectal cancer, of which 695 patients (3%) were younger than 40, showed that the youngest and oldest patients had the highest risk of their disease progressing and of dying, compared to middle-aged patients. When compared to 57-year-olds, the youngest patients had a 30% increased risk of dying from the disease, and, when compared to 61-year-olds, they had a 28% increased risk of their disease progressing and metastasising during the first year of follow-up after randomisation and the start of treatment. The oldest patients had a 72% increased risk of death and a 19% increased risk of their disease metastasising compared to the 57 and 61-year-olds during the follow-up period.

Dr Christopher Lieu, MD, an assistant professor at the University of Colorado (USA), will tell the congress: "Although colorectal cancer occurs in only 4.6% of patients who are younger than 50, the incidence of the disease has been increasing at a rate of 1.5% per year from 1992 to 2005 in this age group. The most dramatic increases have been observed in the 20-29 year-old group, where there has been an annual 5.2% increase in cases in men and a 5.6% increase in women, and in the 30-39 year-old group, where there has been an annual 3% increase in men and a 2% increase in women. [3]

"The reasons why the incidence is increasing in younger patients remain unknown, although genetic predisposition, environmental factors, fewer early cancer detections in this population, or a combination of these factors are
'/>"/>

Contact: José Abad
ecco2013press@gmail.com
ECCO-the European CanCer Organisation
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. HPV Linked to Growing Number of Young Adults with Oropharyngeal Cancer
2. HPV linked to growing number of young adults with oropharyngeal cancer
3. Adult cancer patients younger than 50 with limited brain mets have improved OS after SRS alone
4. BloomingKids Releases Android Apps for Teaching Autistic, Young, and Learning-Disabled Kids
5. Comprehensive Arthroscopic Management - CAM Procedure - Successfully Delays Shoulder Replacement for Young, Active Patients with Shoulder Osteoarthritis
6. Federal Grant of $275,000 Funds Study of Young Adult Attitudes Toward Flavored Tobacco
7. Federal grant of $275,000 funds study of young adult attitudes toward flavored tobacco
8. Why do young adults start smoking?
9. Hawkins Parnell Thacktson & Young LLP Elects Five New Partners
10. Researcher gets National Science Foundations most prestigious award for young faculty
11. New Study Highlights Young People As a Philanthropic Force
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/2/2015)... ... August 03, 2015 , ... A new Phase I research study is looking ... is led by Kenneth G. Lucas, M.D. , chief of the division of ... colleagues at Kosair Children’s Hospital and in the UofL Department of ...
(Date:8/2/2015)... ... August 02, 2015 , ... ... the supportive muscles and connective tissues of a woman’s pelvic organs (uterus, ... damage include straining, heavy lifting, obesity, constipation, multiple vaginal deliveries, genetics, smoking, ...
(Date:8/1/2015)... ... August 02, 2015 , ... AlignLife Office Coordinator Heather ... continuity of care for patients at this natural health care center in Winamac. , ... Mary Heal said. "Heather's role is vital to our approach because we want to ...
(Date:8/1/2015)... ... August 01, 2015 , ... Western University of ... profession” that comprises a growing percentage of U.S. physicians, and reflects the diversity ... one part of the message delivered by John W. Becher, DO, president of ...
(Date:8/1/2015)... ... 01, 2015 , ... The condition where veins are enlarged and gnarled is ... pain and discomfort. Those who spend a lot of time on their feet and ... is doing what it can to create awareness and provide a cure in observance ...
Breaking Medicine News(10 mins):Health News:UofL Physicians Conducting Vaccine Trial for Children with Relapsed Tumors at Kosair Children’s Hospital 2Health News:Minimally Invasive and Robotic Treatment for Pelvic Organ Prolapse Now Available from the Specialists at Women’s Excellence in Bladder Control 2Health News:New Patient Advocate Enhances Natural Health Care 2Health News:COMP-Northwest Welcomes Class of 2019 2Health News:COMP-Northwest Welcomes Class of 2019 3Health News:COMP-Northwest Welcomes Class of 2019 4Health News:COMP-Northwest Welcomes Class of 2019 5Health News:Northeast Houston Vein Center Warns Men about Varicose Veins 2Health News:Northeast Houston Vein Center Warns Men about Varicose Veins 3
... , , PITTSBURGH, ... 15 nonprofit organizations in Pennsylvania and beyond to assist programs supported ... Employee Volunteer Grant Program, which reinforces the company,s appreciation for employees ... out their missions in the community. , , ...
... following is being released by the U.S. Census Bureau: , ... What: The U.S. Census Bureau will hold ... report: Income, Poverty, and Health Insurance Coverage in the United States: ... Population Survey (CPS). , , The Web ...
... SUNNYVALE, Calif., Sept. 9 Prostate cancer remains one of the ... six men will develop prostate cancer.(1) It is also the second-leading cause ... that many men at risk for the cancer still aren,t aware of ... conducted late last year, reveals that nearly 50% of men aged 40 ...
... , INCLINE VILLAGE, Nev., Sept. 9 PDL ... John P. McLaughlin, the company,s president and chief executive officer, will ... New York City on Wednesday, September 16, 2009 at 11:00 a.m. ... and subsequently archived webcast of the conference call, go to the ...
... the cancer causing effects of the second most prescribed group ... rest, following the largest ever study into their use. ... for chronic acid reflux, or ,heartburn, a painful burning sensation ... almost a third of people in developed countries. Regular ...
... Birmingham (UAB) researchers have found that the cost of ... human immunodeficiency virus (HIV) is generally less expensive than ... The study, published in the International ... relied on treatment-cost estimates from previous research studies and ...
Cached Medicine News:Health News:Highmark Inc. Awards $7,500 to 15 Pennsylvania Nonprofit Organizations 2Health News:Highmark Inc. Awards $7,500 to 15 Pennsylvania Nonprofit Organizations 3Health News:Highmark Inc. Awards $7,500 to 15 Pennsylvania Nonprofit Organizations 4Health News:Census Bureau to Announce Findings for Income, Earnings, Poverty and Health Insurance Coverage 2Health News:Survey Shows At-Risk Men Lacking In Prostate Cancer Knowledge 2Health News:Survey Shows At-Risk Men Lacking In Prostate Cancer Knowledge 3Health News:Survey Shows At-Risk Men Lacking In Prostate Cancer Knowledge 4Health News:Survey Shows At-Risk Men Lacking In Prostate Cancer Knowledge 5Health News:Survey Shows At-Risk Men Lacking In Prostate Cancer Knowledge 6Health News:Survey Shows At-Risk Men Lacking In Prostate Cancer Knowledge 7Health News:Survey Shows At-Risk Men Lacking In Prostate Cancer Knowledge 8Health News:Survey Shows At-Risk Men Lacking In Prostate Cancer Knowledge 9Health News:Major clinical study rejects cancer safety fears of most common heartburn treatment 2Health News:UAB researchers find TB-prevention therapy is cost-effective option 2
(Date:7/31/2015)... , July 31, 2015 ... 2015 market research report that provides an overview ... using data sourced from in-house databases, secondary and ... and needles market products pipeline spread across 124 ... with 73 tables and 5 figures is now ...
(Date:7/31/2015)... , July 31, 2015 Quietly, ... of experience, the domestic pharmaceutical industry is strong, with ... products to high international standards. One place ... is in sub-Saharan Africa: Morocco has quietly become the ... South Africa . Indeed, Moroccan pharma companies ...
(Date:7/31/2015)... CHICAGO , July 31, 2015 ... Composition Analyzers Market by Product (Bioimpedance Analyzers (BIA), Dual-Energy ... and Hydrostatic Weighing) - Global Analysis & Forecast to ... Market was pegged at $911.1 Million 2014 and is ... at a CAGR of 9.4% from 2014 to 2019. ...
Breaking Medicine Technology:Syringes and Needles Market Products Pipeline Review 2015 Report 2Syringes and Needles Market Products Pipeline Review 2015 Report 3Syringes and Needles Market Products Pipeline Review 2015 Report 4Syringes and Needles Market Products Pipeline Review 2015 Report 5PharmaBoardroom Releases New Morocco Pharmaceuticals Report 2PharmaBoardroom Releases New Morocco Pharmaceuticals Report 3Body Composition Analyzers Market Worth $1,425.7 Million by 2019 2Body Composition Analyzers Market Worth $1,425.7 Million by 2019 3Body Composition Analyzers Market Worth $1,425.7 Million by 2019 4
... Hospital of Philadelphia announces a grant of $100,000 ... Program dedicated to providing pediatric specialty consultations to ... "Thanks to the support of ... Philadelphia will be able to embark on a ...
... Six years ago, before smartphones were a veritable cornerstone ... Michigan joined an initiative to begin using similar handheld ... prescribe medications for their patients.  Today, ... (SEMI) reports that more than 7,500 physicians in the ...
Cached Medicine Technology:The Verizon Foundation Donates $100,000 to Launch Telemedicine Pilot Program at The Children's Hospital of Philadelphia 2Entering its Prime: Southeast Michigan ePrescribing Initiative, One of the Nation's Longest Running ePrescribing Programs, Increases Enrollment by 33 Percent; Kicks off Seventh Year 2Entering its Prime: Southeast Michigan ePrescribing Initiative, One of the Nation's Longest Running ePrescribing Programs, Increases Enrollment by 33 Percent; Kicks off Seventh Year 3Entering its Prime: Southeast Michigan ePrescribing Initiative, One of the Nation's Longest Running ePrescribing Programs, Increases Enrollment by 33 Percent; Kicks off Seventh Year 4Entering its Prime: Southeast Michigan ePrescribing Initiative, One of the Nation's Longest Running ePrescribing Programs, Increases Enrollment by 33 Percent; Kicks off Seventh Year 5Entering its Prime: Southeast Michigan ePrescribing Initiative, One of the Nation's Longest Running ePrescribing Programs, Increases Enrollment by 33 Percent; Kicks off Seventh Year 6Entering its Prime: Southeast Michigan ePrescribing Initiative, One of the Nation's Longest Running ePrescribing Programs, Increases Enrollment by 33 Percent; Kicks off Seventh Year 7
For the quantitative in vitro determination of Alanine Aminotransferase (ALT) in serum and plasma....
... Anteroir Cervical System, in conjunction with adjunctive ... collar), is intended for use in single ... as a means to maintain the relative ... This device is not intended to be ...
The Tag-It™ Cystic Fibrosis ASR reagents can be used by high complexity CLIA approved laboratories for detection of up to 70 mutations and 6 variants (polymorphisms) in the cystic fibrosis tran...
The Tag-It™ Cystic Fibrosis ASR reagents can be used by high complexity CLIA approved laboratories for detection of up to 70 mutations and 6 variants (polymorphisms) in the cystic fibrosis tran...
Medicine Products: