Navigation Links
You have your MoM's ions
Date:3/9/2010

Hip replacement patients with metal-on-metal (MoM) implants (both the socket and hip ball are metal) pass metal ions to their infants during pregnancy, according to a new study presented today at the 2010 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). Data showed there is a correlation between cobalt and chromium levels in the mother and those in her infant at the time of delivery.

"Although the affects of metal ions in maternal and fetal subjects are unknown, the fact that the placenta is not a complete barrier to the transport of these metals is noteworthy," said Joshua J. Jacobs, MD, Professor and Chairman of Orthopaedic Surgery at Rush University Medical Center in Chicago. "As metal-on-metal implants increase in popularity and use, especially among young, active patients, women of child-bearing age and their doctors should be aware of these findings when considering their hip replacement implant options."

Researchers evaluated three patients who had either a unilateral (only on one hip) MoM primary total hip arthroplasty or unilateral MoM hip resurfacing joint replacement and no other metal implant in the body. The implant group's metal ion levels were compared within the group, between mothers and their infants, and to those of a Control Group comprising seven women of child-bearing age (mean age of about 32 years) who did not have any metal implants and their infants.

For all subjects, maternal and umbilical cord blood was obtained at the time of delivery and tested for blood serum concentrations of titanium, nickel, cobalt and chromium using inductively coupled plasma mass spectrometry (ICP-MS), a highly sensitive technique that can detect trace amounts of metals in biological samples.

The data found:

  • Mothers with MoM implants and their offspring had elevated Chromium and cobalt levels compared to the cohort without metal implants.
  • A correlation existed between maternal and infant cobalt and chromium levels in the Implant Group, while the Control Group showed no correlation.
  • Offspring of women with MoM implants had about half the levels of cobalt in their bloodstream as their mothers and approximately 15 percent of their mother's chromium levels, while there was no significant difference among ion levels between mothers and infants in the Control Group.
  • There was no statistically significant differences in levels of titanium or nickel among any of the cohorts.

Dr. Jacobs noted that because the cobalt and chromium levels of the infants did not increase to those of their mothers, the data suggests the placenta does modulate the transfer of metal ions to the fetus.

"The next step is to find out what, if any affect metal ions have on fetal or infant development," he said. "The best way to do that would be through the establishment of a national joint registry by which clinicians could input and access long-term data."

He added that, in the meantime, medical device companies are feverishly working to develop new technologies that will reduce the release of ions through improvements in wear and corrosion properties of metal implants. "Any advancements in this area will directly benefit patients," he said.


'/>"/>

Contact: Kristina K. Findlay
findlay@aaos.org
847-384-4034
American Academy of Orthopaedic Surgeons
Source:Eurekalert

Related medicine news :

1. Children of depressed moms do better when dad is involved, SLU researcher finds
2. Monkey Moms Use Baby Talk, Too
3. Stressed-Out Moms Carry Babies on the Right
4. Mothers Know Best: NFL Moms Team With Eddie George to Showcase a Better Way to a Healthier Lifestyle
5. March of Dimes, Experts for Moms and Babies, Launches Podcast
6. Abbott Again Honored as Top Company for Working Moms
7. Stop eating for two: obese moms-to-be should gain less weight than currently recommended
8. Brands Tackle the Childhood Obesity Issue During M2Moms(TM) - The Marketing-To-Moms Conference
9. Pink Power Moms Unite in Atlanta for Day of Pampering and Recognition
10. Jane Fonda and Bright Starts(TM) Celebrates Pink Power Moms at Susan G. Komen for the Cure Pink Tie Ball
11. Kaiser Permanente/Harvard Medical School study links lack of sleep to weight gain for new moms
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2017)... London UK (PRWEB) , ... March 27, 2017 ... ... agility and ability to gain site attention and engagement over the household brands ... educational webinar will discuss how partnering with the right outsourcing payments ...
(Date:3/27/2017)... (PRWEB) , ... March 27, 2017 , ... A study ... Buckingham MD, and his colleague, Sudeep Roy, MD, was recently published in the ... Electrocautery Efficacy in Rhytidectomy” details Drs. Buckingham and Roy’s study on the use of ...
(Date:3/27/2017)... ... March 27, 2017 , ... Buzzies parent company, The ... for Rent the Runway Foundation and UBS’ Project Entrepreneur. Mayo will present her pitch ... 8. , Project Entrepreneur’s second annual venture competition ignites bold ideas by providing ...
(Date:3/27/2017)... Niles, IL (PRWEB) , ... March 27, 2017 ... ... testing systems, recently received the CE Certificate of Conformity for the Smart System® ... meet or exceed the highest industry standards and specifications such as ANSI, ISO ...
(Date:3/27/2017)... ... March 27, 2017 , ... American Veterinarian™, the leading ... veterinary medicine, announces the launch of Veterinarian’s Money Digest™, a business and financial ... edition of American Veterinarian™. , “We look forward to launching Veterinarian’s ...
Breaking Medicine News(10 mins):
(Date:3/27/2017)... 27, 2017  Twist Bioscience, a company accelerating science ... that it raised an additional $33 million. To date, ... "It is an exciting time to ... and continue to deliver industry-leading gene volume to our ... Emily M. Leproust, Ph.D., CEO of Twist Bioscience. "We ...
(Date:3/27/2017)... , March 27, 2017  PhaseRx, Inc. (NASDAQ: ... life-threatening inherited liver diseases in children, today reported ... year ended December 31, 2016 and provided an ... "PhaseRx continued to make progress during the fourth ... results from our non-human primate safety study, and with ...
(Date:3/27/2017)... , March 27, 2017 Invivotek, LLC, a ... in vivo pharmacology contract research organization (CRO), ... to its newly expanded preclinical research facility in ... provides a cleaner, renewable energy source to reduce costs ... Completion of the Genesis Solar Farm follows Invivotek,s recent ...
Breaking Medicine Technology: