Navigation Links
Yi-Qi-Zeng-Min-Tang ameliorates insulin resistance in Type 2 diabetic rats
Date:3/15/2011

The prevalence of type 2 diabetes is dramatically increasing throughout the world. Insulin resistance is a hallmark of type 2 diabetes, and it most often precedes the onset of hyperglycemia and predicts development of type 2 diabetes. At present, thiazolidinediones (TZD), the agonists of the peroxisome proliferators-activated receptor γ, are the main agents to improve insulin sensitivity in the liver, adipose tissue, and skeletal muscle, thus improving glycaemic control in patients with type 2 diabetes. Despite the efficacy, some deleterious side effects of TZDs, including rosiglitazone and pioglitazone, have been noted, such as increasing body weight and aggravating heart failure through fluid retention. Therefore, development of new agents may be helpful in the treatment of type 2 diabetic patients with insulin resistance.

A research article published on February 28, 2011 in the World Journal of Gastroenterology addresses this question. The research team led by Professor Wen-Jian Wang from Institute of Chinese Integrative Medicine, Huashan Hospital of Fudan University investigated the effect of the Chinese herbal decoction, Yi-Qi-Zeng-Min-Tang (YQZMT), on insulin resistance in type 2 diabetic rats.

The results of this study indicated that YQZMT has beneficial effect in insulin resistance, glycaemic control, dyslipidemia, free fatty acids and adipocytokines, and does not cause any increase in body weight in high-fat diet and low-dose streptozotocin induced type 2 diabetic rats.

The findings demonstrate that YQZMT displays the insulin sensitization characteristic of rosiglitazone, but unlike rosiglitazone, does not cause any increase in body weight. Administration of YQZMT may be a suitable adjunct for the treatment of insulin resistance patients. Further studies will be required to identify the ingredients and chemicals in YQZMT responsible for the beneficial effects observed in the present study.


'/>"/>

Contact: Ye-Ru Wang
wjg@wjgnet.com
86-105-908-0039
World Journal of Gastroenterology
Source:Eurekalert

Page: 1

Related medicine news :

1. Hormone Outperforms Insulin in Diabetic Mice
2. Experts call for further research into the relationship between insulin therapy and cancer
3. More Info Needed on Problems With Insulin Pumps
4. New Inhaled Insulin Shows Promise for Diabetes
5. Jekyll and Hyde Factor May Control Insulin Function
6. Study Finds That Insulin-Producing Beta Cells Can Be Reborn
7. One Sleepless Night Ups Insulin Resistance
8. Mayo-led research team develop agents that keep insulin working longer
9. New pathway to cheap insulin
10. Nicer than needles: Insulin pills for diabetes finally in clinical trials
11. Diabetic potential to create own insulin
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... Fort Worth, TX (PRWEB) , ... October 13, ... ... and financial planning agency serving communities in the greater Dallas, Miami, and Raleigh ... a young boy fighting to overcome a rare and deadly chromosome abnormality. , ...
(Date:10/13/2017)... ... 2017 , ... While it’s often important to take certain medications during the ... Texas, has identified a solution. , She developed a prototype for MOTION LIGHT-UP PILL ... it eliminates the need to turn on a light when taking medication during the ...
(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a ... utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil will revolutionize the ... a CBD form that can be easily incorporated into liquid products, while reducing costs ...
(Date:10/13/2017)... ... ... Apple Rehab Shelton Lakes , which specializes in the delivery of sub-acute ... of a disaster drill on October 3rd. , Apple Rehab participated with the Shelton ... well as the Connecticut Long Term Care Mutual Aid Plan (LTC-MAP). The LTC-MAP ...
(Date:10/13/2017)... ... 2017 , ... Ellevate Network, the leading network for professional women, brought together ... equality at their inaugural Summit in New York City in June. The event was ... of over 3 million. To watch the Mobilize Women video, click here . ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... , Oct. 12, 2017 AVACEN Medical ... the company with their  2017 New Product Innovation Award ... on extensive primary and secondary medical device market research by ... through its first-to-market OTC, drug-free pain relief product, the AVACEN ... approach to treating fibromyalgia widespread pain. ...
(Date:10/12/2017)... West Pharmaceutical Services, Inc. (NYSE: ... drug administration, today announced that it will release third-quarter ... October 26, 2017, and will follow with a conference ... 9:00 a.m. Eastern Time. To participate on the call, ... ID is 94093362. ...
(Date:10/11/2017)...  Caris Life Sciences ® , a leading innovator ... precision medicine, today announced that St. Jude Medical Center,s ... (POA) as its 17 th member. Through participation ... Cancer Institute will help develop standards of care and ... making cancer treatment more precise and effective. ...
Breaking Medicine Technology: