Navigation Links
Yerkes researchers use eye tracking to detect mild dementia in humans
Date:4/15/2009

Researchers at the Yerkes National Primate Research Center, Emory University, developed a test in nonhuman primates that is now using infrared eye tracking to detect mild cognitive impairment (MCI) in humans. The researchers hope the advanced technology will be helpful in predicting the onset of Alzheimer's disease. The test, which is featured in the current online issue of The American Journal of Alzheimer's Disease and Other Dementias, is helping researchers further understand the role of the brain structures critical to human memory.

Individuals who have been diagnosed with MCI show memory loss but relatively preserved abilities in other cognitive areas. However, many individuals with MCI appear to be at a higher risk for developing other forms of dementia, including Alzheimer's disease. Accordingly, individuals with MCI play an important role in the development of research strategies that could lead to early diagnosis and possible prevention of such dementias.

To study the brain changes related to memory loss, Yerkes director and lead researcher Stuart Zola, PhD, developed an infrared eye-tracking test that involves showing individuals one image and then another after a several-second delay. The researchers then repeat the test several minutes later. In doing so, they found patients with MCI spent less time looking at the new picture than control subjects.

"Someone without any impairment spends most of the time focusing on the new image because the person quickly recognizes the previously shown image," says Zola. In contrast, individuals with MCI show less interest in the new image because, as time passes, they may not remember seeing the original image. This is similar to individuals with Alzheimer's disease, who will look at both images equally because they cannot remember seeing the first image," Zola continues.

The results of the study indicate the possibility of detecting dementias much earlier than ever before. By doing so, intervention can begin sooner, which offers hope for more effective treatment and, thus, encouraging outcomes. The researchers plan to follow up the study by tracking and observing study participants to determine whether they develop any forms of dementia.

To listen to Zola's own words about his research involving diagnosing cognitive impairment, access Emory's new Sound Science podcast at http://whsc.emory.edu/soundscience/

For nearly eight decades, the Yerkes National Primate Research Center, Emory University, has been dedicated to conducting essential basic science and translational research to advance scientific understanding and to improve the health and well-being of humans and nonhuman primates. Today, the center, as one of only eight National Institutes of Healthfunded national primate research centers, provides leadership, training and resources to foster scientific creativity, collaboration and discoveries. Yerkes-based research is grounded in scientific integrity, expert knowledge, respect for colleagues, an open exchange of ideas and compassionate, quality animal care.

Within the fields of microbiology and immunology, neuroscience, psychobiology and sensory-motor systems, the center's research programs are seeking ways to: develop vaccines for infectious and noninfectious diseases, such as AIDS and Alzheimer's disease; treat cocaine addiction; interpret brain activity through imaging; increase understanding of progressive illnesses such as Parkinson's and Alzheimer's; unlock the secrets of memory; determine behavioral effects of hormone replacement therapy; address vision disorders; and advance knowledge about the evolutionary links between biology and behavior.


'/>"/>

Contact: Lisa Newbern
lmnewbe@emory.edu
404-727-7709
Emory University
Source:Eurekalert

Related medicine news :

1. Yerkes researchers find link between psychological stress and overeating
2. Yerkes researchers create animal model of chronic stress
3. Stanford researchers find culprit in aging muscles that heal poorly
4. UCLA researchers identify markers that may predict diabetes in still-healthy people
5. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
6. Bipolar disorder relapses halved by Melbourne researchers
7. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
8. High and mighty: first common height gene identified by researchers behind obesity gene finding
9. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
10. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
11. Researchers develop long-lasting growth hormone
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... Lake Orion, Clarkston, Michigan (PRWEB) , ... June ... ... direction with respect to fertility once they have been diagnosed with endometriosis. These ... tolerable intercourse but they also require a comprehensive approach that can help for ...
(Date:6/25/2016)... ... , ... The temporary closing of Bruton Memorial Library on June 21 due to a possible ... often overlooked aspect of head lice: the parasite’s ability to live away from a human ... but a necessary one in the event that lice have simply gotten out of control. ...
(Date:6/25/2016)... ... ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors in ... School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green Hospital ... at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train in ...
(Date:6/25/2016)... Montreal, Canada (PRWEB) , ... June 25, 2016 , ... ... the pursuit of success. In terms of the latter, setting the bar too high ... low, risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort to ... treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain management ... (SCD) is a disorder of the red blood cells, which can cause episodes of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  American Respiratory Labs (ARL), a ... now able to perform sophisticated lung assessments in patients, homes, thanks ... Inc. Patients are no longer limited to having ... PRO ® , ARL patients like Jeanne R. of ... the comfort of her own home. ...
(Date:6/24/2016)... , Belgium , June 24, ... VNRX), today announced the appointment of Dr. ... Directors as a Non-Executive Director, effective June 23, ... Audit, Compensation and Nominations and Governance Committees.  As ... Futcher will provide independent expertise and strategic counsel ...
(Date:6/23/2016)... -- Any dentist who has made an implant supported denture ... of them do not even offer this as a viable ... costs involved. And those who ARE able to offer that ... cost that the majority of today,s patients would not be ... , founder of Dental Evolutions Inc. and inventor of Implanova ...
Breaking Medicine Technology: