Navigation Links
Yerkes researchers use eye tracking to detect mild dementia in humans

Researchers at the Yerkes National Primate Research Center, Emory University, developed a test in nonhuman primates that is now using infrared eye tracking to detect mild cognitive impairment (MCI) in humans. The researchers hope the advanced technology will be helpful in predicting the onset of Alzheimer's disease. The test, which is featured in the current online issue of The American Journal of Alzheimer's Disease and Other Dementias, is helping researchers further understand the role of the brain structures critical to human memory.

Individuals who have been diagnosed with MCI show memory loss but relatively preserved abilities in other cognitive areas. However, many individuals with MCI appear to be at a higher risk for developing other forms of dementia, including Alzheimer's disease. Accordingly, individuals with MCI play an important role in the development of research strategies that could lead to early diagnosis and possible prevention of such dementias.

To study the brain changes related to memory loss, Yerkes director and lead researcher Stuart Zola, PhD, developed an infrared eye-tracking test that involves showing individuals one image and then another after a several-second delay. The researchers then repeat the test several minutes later. In doing so, they found patients with MCI spent less time looking at the new picture than control subjects.

"Someone without any impairment spends most of the time focusing on the new image because the person quickly recognizes the previously shown image," says Zola. In contrast, individuals with MCI show less interest in the new image because, as time passes, they may not remember seeing the original image. This is similar to individuals with Alzheimer's disease, who will look at both images equally because they cannot remember seeing the first image," Zola continues.

The results of the study indicate the possibility of detecting dementias much earlier than ever before. By doing so, intervention can begin sooner, which offers hope for more effective treatment and, thus, encouraging outcomes. The researchers plan to follow up the study by tracking and observing study participants to determine whether they develop any forms of dementia.

To listen to Zola's own words about his research involving diagnosing cognitive impairment, access Emory's new Sound Science podcast at

For nearly eight decades, the Yerkes National Primate Research Center, Emory University, has been dedicated to conducting essential basic science and translational research to advance scientific understanding and to improve the health and well-being of humans and nonhuman primates. Today, the center, as one of only eight National Institutes of Healthfunded national primate research centers, provides leadership, training and resources to foster scientific creativity, collaboration and discoveries. Yerkes-based research is grounded in scientific integrity, expert knowledge, respect for colleagues, an open exchange of ideas and compassionate, quality animal care.

Within the fields of microbiology and immunology, neuroscience, psychobiology and sensory-motor systems, the center's research programs are seeking ways to: develop vaccines for infectious and noninfectious diseases, such as AIDS and Alzheimer's disease; treat cocaine addiction; interpret brain activity through imaging; increase understanding of progressive illnesses such as Parkinson's and Alzheimer's; unlock the secrets of memory; determine behavioral effects of hormone replacement therapy; address vision disorders; and advance knowledge about the evolutionary links between biology and behavior.


Contact: Lisa Newbern
Emory University

Related medicine news :

1. Yerkes researchers find link between psychological stress and overeating
2. Yerkes researchers create animal model of chronic stress
3. Stanford researchers find culprit in aging muscles that heal poorly
4. UCLA researchers identify markers that may predict diabetes in still-healthy people
5. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
6. Bipolar disorder relapses halved by Melbourne researchers
7. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
8. High and mighty: first common height gene identified by researchers behind obesity gene finding
9. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
10. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
11. Researchers develop long-lasting growth hormone
Post Your Comments:
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... ... share medical images have been lifted as IMAGE Information Systems launches MED-TAB™ -- ... of North America Annual Meeting from November 29 to December 4, 2015. ...
(Date:12/1/2015)... ... December 01, 2015 , ... For many X-rays ... film for accurate interpretation by the radiologist. The marking utensils are so small, ... Calif., has found a way to alleviate this problem. , He developed the ...
(Date:12/1/2015)... , ... December 01, 2015 , ... ... of Excellence (BHCOE) today announced that the organization has awarded Education and Developmental ... with a Distinguished Award. The award celebrates exceptional special needs providers that excel ...
(Date:12/1/2015)... Burlington, MA (PRWEB) , ... December 01, 2015 , ... ... the release of Clarity, the latest addition to the devices for sale in the ... technologies, 755 nm Alexandrite and long-pulsed 1064 nm Nd:YAG lasers, into a single platform ...
(Date:12/1/2015)... ... December 01, 2015 , ... XTC Semifinals 2016 - CES, Las Vegas, ... Las Vegas for CES 2016, the world’s largest Consumer Electronic Show, where they will ... Shapiro, Founding Partner of Pacific Investments Veronica Serra, and venture capitalist Tim Draper among ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... DUBLIN , Dec. 01, 2015 ... ) has announced the addition of ... Testing Market: Campylobacter, Cryptosporidium, E. Coli, ... Yersinia" report to their offering. ... announced the addition of the ...
(Date:12/1/2015)... , Dec. 1, 2015 CytRx Corporation (NASDAQ: ... specializing in oncology, today announced that it has reached ... pivotal global Phase 3 clinical trial of aldoxorubicin in ... originally estimated to be completed in Q1 2016. The Phase ... under a Special Protocol Assessment from the FDA at ...
(Date:12/1/2015)... --  Craneware, Inc ., the healthcare market leader ... company will showcase a new version of its ... at the American Society for Health-System Pharmacists (ASHP) ... features are focused on simplifying and streamlining the ... pharmacy charges to ensure compliance and optimal revenue ...
Breaking Medicine Technology: