Navigation Links
Yerkes researchers create animal model of chronic stress
Date:9/3/2008

In an effort to better understand how chronic stress affects the human body, researchers at the Yerkes National Primate Research Center and the Department of Psychiatry and Behavioral Sciences, Emory University, have created an animal model that shows how chronic stress affects behavior, physiology and reproduction.

Developing the animal model better positions the researchers to understand the neurohormonal causes of such stress and the body reaction in order to develop more effective treatment options for humans. The study is available in the current online edition of Molecular Psychiatry.

According to lead researcher Mark Wilson, PhD, chief of the Division of Psychobiology at Yerkes, "Chronic stress can lead to a number of behavioral changes and physical health problems, including anxiety, depression and infertility."

Via the animal model, the researchers found corticotropin releasing factor (CRF) is a key neurohormone involved in stress response. Wilson explains, "CRF is located in several different brain regions, serving different functions. Its release is important for our ability to adapt to every day stressors and to maintain our physical and emotional health."

In response to stress, CRF levels rise; CRF levels decrease when the stressor no longer is present. Chronic stress, however, increases the length and volume of expression of CRF in areas of the brain associated with fear and emotion, including the amygdala. Such chronic stress changes the body's response, and the resulting increased expression of CRF is thought to be the cause of such health-related stress problems including anxiety, depression and infertility.

To study the importance of CRF, the research team used a viral vector to increase the production of CRF in the amygdala of female rats.

"In our study, rats that continuously were exposed to CRF from this area of the brain experienced anxious and depressive behavior, decreased lib
'/>"/>

Contact: Emily Rios
erios@emory.edu
404-727-7732
Emory University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Yerkes researchers find link between psychological stress and overeating
2. Stanford researchers find culprit in aging muscles that heal poorly
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
5. Bipolar disorder relapses halved by Melbourne researchers
6. Cell that triggers symptoms in allergy attacks can also limit damage, Stanford researchers find
7. High and mighty: first common height gene identified by researchers behind obesity gene finding
8. Researchers estimate about 9 percent of US children age 8 to 15 meet criteria for having ADHD
9. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
10. Researchers develop long-lasting growth hormone
11. Jefferson immunology researchers halt lethal rabies infection in brain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... 2014 Medical Solutions , ... happy to announce that our co-founder and CFO, ... Analysts’ Staffing 100 for 2014. Anderson was also ... influential people in the staffing industry,” in 2013.     ... 13th-largest healthcare staffing company in the U.S., was ...
(Date:10/22/2014)... HealthDay Reporter , TUESDAY, Oct. 21, ... Ebola cases in Dallas. But, mental health specialists say overblown ... President Barack Obama on Friday appointed an Ebola "czar" to ... two Dallas nurses who cared for a Liberian man who ... But the U.S. cases are miniscule in the context ...
(Date:10/22/2014)... 2014 The Louis W. ... dedicated to distribute health information technology innovation to ... announced the development of six key guiding principles ... receiving healthcare. These are an expansion of the ... care that is respectful of and responsive to ...
(Date:10/22/2014)... During the Western United States’ worst ... dangerously low, Southern Oregon’s water is proving resistant to ... lowest mountain snow pack on record in 2014, remain ... autumn.* That was the observation of journalist-hikers Art Bernstein ... Southern Oregon,” during an interview with water advocate Sharon ...
(Date:10/22/2014)... (PRWEB) October 22, 2014 Losing Weight Your ... industry is staring you in the face, it certainly can ... not do your body an extra favor by doing it ... tempting crash diets. Instead, listen to your body, exercise regularly, ... Exercise is essential to losing weight; you need to exercise ...
Breaking Medicine News(10 mins):Health News:Medical Solutions Co-Founder/CFO Scott Anderson Named to Staffing Industry Analysts’ 2014 Staffing 100 2Health News:Medical Solutions Co-Founder/CFO Scott Anderson Named to Staffing Industry Analysts’ 2014 Staffing 100 3Health News:Ebola Anxiety: A Bigger Threat Now Than the Virus Itself 2Health News:Ebola Anxiety: A Bigger Threat Now Than the Virus Itself 3Health News:The Sullivan Institute for Healthcare Innovation Announces Release of Guiding Principles for Patient Experience-Centered Care 2Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 2Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 3Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 4Health News:ReductionGuruMD Presents Ways to Improve Your Weight Loss Results 2
... joint venture with a South African company that will support ... joint venture between Ranbaxy and South Africa based Community Investment ... company to sell the drugs in Africa. The CEO of ... permit the company to make the drugs available at a ...
... Sydney have expressed hope over their newly developed drug ... is also claimed to improve the clinical outcome in ... and post transplant recipients. ,The unique drug ... promising results have been obtained. It has been found ...
... the effect of parental conflict on learning and behavioral ... to the consequent sleep disorders in children. //Although it ... parents lead to behavior and learning problems in children, ... new study, published in the latest issue of Child ...
... The bird flu’s virulent H5N1 strain has been discovered in ... Health (OIE). This has given rise to fears that a ... fist incidence of bird flu in the Continent. Preventive measures ... Nigerian authorities, with regard to animals and birds. ...
... disease buster might be now challenged. ,A University of Chicago ... grains had no reduced risk of two types of cancer or ... drawback of the study as perceived by some experts is that ... unhealthy food than the healthy foods., ,As said by Dr. ...
... parents are more likely to suffer from depression as ... are unmarried. Florida State University researchers, and researchers from ... this interesting finding. Researchers hypothesize that the constant concern ... adult children could be responsible for the same. ...
Cached Medicine News:Health News:Parental Conflict Can Lead to Sleep Disorders in Children 2Health News:Fat isn't all that bad: Reduction no predecessor of reduced disease 2Health News:Depression More Likely To Affect Parents, Rather Than Non-Parents 2
(Date:10/22/2014)... , Oct. 22, 2014  Quest Diagnostics (NYSE: ... information services, today announced that its Board of Directors ... a director, effective December 1, 2014. Including Dr. Leiden, ... is the Chairman, President and CEO of Vertex Pharmaceuticals. ... scientific and commercial experience in the pharmaceutical and biotechnology ...
(Date:10/22/2014)... , Oct. 22, 2014 Moms are ... health trackers for themselves and their kids, according to ... Report: Health & Fitness Go Mobile for Moms, the ... Series. BabyCenter, the number 1 pregnancy and parenting web ... that 55 percent of moms surveyed say they can,t ...
(Date:10/22/2014)... , Oct. 22, 2014  With a vision ... health medications, a Global Pharmaceutical and Biotech manufacturer ... technology and turnkey solution to protect their animal ... http://photos.prnewswire.com/prnh/20141021/153438 Photo - ... was serialized and aggregated by the Xyntek and ...
Breaking Medicine Technology:Quest Diagnostics Adds Jeffrey M. Leiden, M.D., Ph.D., to Board of Directors 2Quest Diagnostics Adds Jeffrey M. Leiden, M.D., Ph.D., to Board of Directors 3BabyCenter Finds Mom Ready to Live the "Measured Life" in its U.S. Mobile Mom 2014 Report: Health & Fitness Go Mobile for Moms 2BabyCenter Finds Mom Ready to Live the "Measured Life" in its U.S. Mobile Mom 2014 Report: Health & Fitness Go Mobile for Moms 3BabyCenter Finds Mom Ready to Live the "Measured Life" in its U.S. Mobile Mom 2014 Report: Health & Fitness Go Mobile for Moms 4Xyntek and Antares Serialization Solution Protects Pets Too! 2
... 17, 2011 Clontech Laboratories, Inc., a wholly-owned ... release of the Tet-Express Inducible Expression System ... expression technology yet. At the heart of this ... Clontech,s Tet-Off® Advanced transcriptional activator protein (the Tet-Express ...
... Echo Therapeutics, Inc. (OTC Bulletin Board: ... as a non-invasive, wireless, transdermal continuous glucose monitoring (tCGM) ... delivery, announced that development of the commercially ready Symphony ... that the system will be ready for demonstration in ...
Cached Medicine Technology:Announcement - Clontech Laboratories, Inc. Releases the Tet-Express™ Inducible Expression System 2Announcement - Clontech Laboratories, Inc. Releases the Tet-Express™ Inducible Expression System 3Echo Therapeutics Reports Symphony™ tCGM System Ahead of Schedule 2Echo Therapeutics Reports Symphony™ tCGM System Ahead of Schedule 3
... been selling replacement bulbs on ... we are extremely proud of ... out our catalog of replacement ... light bulbs specials. ,Check ...
... has been selling replacement bulbs ... and we are extremely proud ... Check out our catalog of ... discount light bulbs specials. ...
... Direct has been selling replacement ... 1996, and we are extremely ... guarantee. Check out our catalog ... our discount light bulbs specials. ...
... Bulb Direct has been selling ... since 1996, and we are ... satisfaction guarantee. Check out our ... see our discount light bulbs ...
Medicine Products: