Navigation Links
Yale researchers find double doses of chicken pox vaccine most effective
Date:1/4/2011

When vaccinating children against varicella (chicken pox), researchers at Yale School of Medicine have found, two doses are better than one. In fact, the odds of developing chicken pox were 95 percent lower in children who had received two doses of the vaccine compared with those who had received only one dose.

Published in the February 1 issue of Journal of Infectious Diseases, the study was led by Eugene D. Shapiro, M.D., professor in the Department of Pediatrics at Yale and his colleagues at Yale and Columbia universities.

The Centers for Disease Control and Prevention (CDC) began recommending a single dose of chicken pox vaccine for children ages 1 to 13 in 1995. The chicken pox rate fell drastically and studies showed that the effectiveness of one dose was 86 percent. But there was still a high rate of breakthrough illness in immunized children. The CDC changed the immunization policy for chicken pox in 2006, adding a second dose for children ages 4 to 6. In this study, Shapiro and his team showed that the effectiveness of two doses is 98.3 percent.

Past studies have suggested that two doses of varicella vaccine are linked to higher antibody levels than one dose, but this is the first study to assess the clinical effectiveness of two doses of the vaccine in the general population. In a survey of Connecticut children, Shapiro and his team discovered 71 cases of chicken pox in children ages 4 and older. None of these children had received two doses of vaccine; 66 (93 percent) had received one dose and five (7 percent) had received no vaccine.

"We weren't surprised to find that two doses of varicella vaccine are highly effective and are more likely to prevent varicella than a singe dose," said Shapiro. "The findings confirm that, at least in the short term, the policy of routinely administering two rather than one dose of varicella vaccine is sensible. Other countries that are routinely immunizing children with varicella vaccine may consider changing to a two-dose regimen."

Because it has only been four years since the CDC policy change, Shapiro also recommends that there be continued monitoring of the effectiveness of two doses to assure that its high degree of effectiveness is sustained.


'/>"/>

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University
Source:Eurekalert

Related medicine news :

1. Researchers map all the fragile sites of the yeast Saccharomyces cerevisiaes genome
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Researchers discover new way to kill pediatric brain tumors
4. Researchers Who Discovered First Genes for Stuttering will Present Findings to the National Stuttering Association
5. Researchers create drug to keep tumor growth switched off
6. Urine protein test might help diagnose kidney damage from lupus, UT Southwestern researchers find
7. GUMC researchers say flower power may reduce resistance to breast cancer drug tamoxifen
8. Clemson researchers develop hands-free texting application
9. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
10. Researchers chart genomic map spanning over 2 dozen cancers
11. Researchers discover second protective role for tumor-suppressor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2017)... (PRWEB) , ... May 24, 2017 , ... ... practice is offering holistic pediatric dentistry options for its patients on Long Island, ... the patient’s entire physical well being, and is one of the biggest trends ...
(Date:5/24/2017)... ... 24, 2017 , ... Technique, technique, technique – with a dash of common ... strength training and exercise or simply lifting heavy objects, advises Dr. Kaliq Chang, interventional ... Dr. Chang says. “Improper technique in lifting anything heavy or an attempt to lift ...
(Date:5/23/2017)... ... May 23, 2017 , ... Allegheny Health Network and the ... Center for Women’s Behavioral Health at West Penn Hospital , a unique facility ... suffering from pregnancy-related depression. Construction of the Center is underway with a scheduled ...
(Date:5/23/2017)... California (PRWEB) , ... May 23, 2017 , ... ... management (PHM) technology and a 2017 Best in KLAS category winner, has named ... market position to extend and enhance its technology platform and product offerings,” says ...
(Date:5/23/2017)... ... May 23, 2017 , ... By all indications, and due ... County. While officials call for diligence, asking homeowners to scout for any open water ... concerns. Along with the annoying buzz of mosquitos is the buzz associated with potential ...
Breaking Medicine News(10 mins):
(Date:5/10/2017)... , May 10, 2017 Global Health Intelligence ... Latin America , published its 2017 ranking of ... is based on extensive data analysis from GHI,s hospitals ... hospitals database for the region. The GHI database covers 86% ... offering more than 130 data points for each institution in ...
(Date:5/9/2017)... , May 9, 2017  Demonstrating its ... board of directors for the Pharmaceutical Research and ... for membership. Biopharmaceutical companies will now have to ... order to be eligible to join PhRMA. ... the board is sending a clear message that ...
(Date:5/6/2017)... 2017   Provista , a proven leader in the ... today announced Jim Cunniff as the company,s new ... business experience to Provista, including most recently serving as the ... California . He assumed his new role with Provista ... fit for Provista," says Jody Hatcher , president, Sourcing ...
Breaking Medicine Technology: