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Yale Cancer Center's tip sheet for the 50th Annual Meeting of ASCO May 30 - June 3, 2014
Date:5/22/2014

in the control group.

Previous findings from the HOPE study showed exercise improved AI-associated joint pain, but results from this analysis of favorable decreases in body weight, fat and CRP found these markers did not mediate the beneficial effect of exercise on AI joint pain. Further HOPE analyses will be conducted to determine the mechanism(s) of how exercise improves AI joint pain.

Keywords: breast cancer; recurrence; survivorship; biomarkers; obesity; weight loss; exercise; quality of life

Estimating the impact of screening on three decades of cervical cancer incidence. (#1518)

Authors: Daniel Xiao Yang, Pamela R. Soulos, Brigette Davis, Cary Gross, James B. Yu; Yale School of Medicine, New Haven, CT

Yale researchers found that cervical cancer screening via Pap smear over three decades (1976-2009) was associated with an estimated reduction of up to half a million cervical cancer cases of all stages, with rates of reduction significant for African-American women. After rising steadily from 1951-1981, the percentage of all adult women who received cervical cancer screening stabilized at 71.7% in 1982 to 73.8% in 2010. Overall, from 1976 to 2009, there was a significant decrease in the incidence of early stage cervical cancer, from 10.2 to 5.4 cases per 100,000 women (p < .001). Late stage disease incidence also decreased, from 5.2 to 3.7 cases per 100,000 women (p < .001). After adjusting for "pre-screening era" rates of cervical cancer, we estimate that Pap smears were associated with a reduction of between 105,000 to 492,000 cases of cervical cancer over the past three decades in the U.S. The combined incidence among black women decreased from 26.9 to 9.7 cases per 100,000 women (p < .001), a greater decline compared to that of white women (13.7 to 8.5 cases per 100,000, p < .001), and women of other races (16.0 to 7.4 cases per 100,000, p < .001). We estimate that a large number of early and late stage ce
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Contact: Vicky Agnew
vicky.agnew@yale.edu
203-785-7001
Yale University
Source:Eurekalert

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