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Xceed Molecular Signs University of Florida to Strategic Collaborator Program; Focus on Developing New Molecular Test to Diagnose Early-Stage Bladder Cancer
Date:4/16/2008

WELLESLEY, Mass., April 16 /PRNewswire/ -- Xceed Molecular, a pioneer in the development of cost-effective, easy-to-use gene-expression analysis systems, announced that the University of Florida has joined Xceed's Strategic Collaborator program. Xceed will work with primary researchers, Charles Joel Rosser, MD (Department of Urology) and Steve Goodison, MD (Department of Surgery), to perform initial verification and validation of an expression signature that has shown promise as a way to differentiate bladder cancer from other conditions using voided urine samples.

As part of the collaboration, Xceed and the University of Florida will test approximately 700 samples from patients previously identified to have either cancerous or non-cancerous bladder tumors to verify that the expression signature is useful in distinguishing the two populations. Xceed will run the first 100 samples on the company's Ziplex(R) System in its expression-services laboratories in Toronto to optimize the performance of the signature on the Ziplex platform. The company will also provide a Ziplex System to the university, where the study on the remaining samples will be completed. If the signature is successfully validated, Xceed and the University of Florida will continue to work together to pursue subsequent clinical testing to validate the signature for use in patient management. Specific terms were not disclosed.

Nearly 70,000 Americans are diagnosed with bladder cancer every year. The symptoms, voiding problems and/or blood in the urine, are common to many other health issues (e.g. urinary tract infections, kidney stones, trauma). Today, bladder cancer is diagnosed and monitored with cystoscopy -- an invasive, uncomfortable, and costly procedure in which a scope is inserted through the urethra to visualize the bladder. Suspicious areas are biopsied and sent to the pathology lab. The skill of the doctor performing the procedure is of paramount importance -- low-grade a
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