Navigation Links
X-rays for early Alzheimer's disease detection
Date:6/16/2009

UPTON, NY Researchers at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have demonstrated a new, highly detailed x-ray imaging technique that could be developed into a method for early diagnosis of Alzheimer's disease. The technique has previously been used to look at tumors in breast tissue and cartilage in human knee and ankle joints, but this study is the first to test its ability to visualize a class of miniscule plaques that are a hallmark feature of Alzheimer's disease. Their results will appear in a July 2009 edition of the journal NeuroImage.

Images of the brain of a transgenic mouse obtained through histology and the corresponding brain region imaged with DEI in computed tomography mode. Scientists have long known that Alzheimer's disease is associated with plaques, areas of dense built-up proteins, in the affected brain. Many also believe that these plaques, called amyloid beta (A) plaques after the protein they contain, actually cause the disease. A major goal is to develop a drug that removes the plaques from the brain. However, before drug therapies can be tested, researchers need a non-invasive, safe, and cost-effective way to track the plaques' number and size.

That is no easy task: A plaques are extremely small on the micrometer scale, or one millionth of a meter. And conventional techniques such as computed tomography (CT) poorly distinguish between the plaques and other soft tissue such as cartilage or blood vessels.

"These plaques are very difficult to see, no matter how you try to image them," said Dean Connor, a former postdoctoral researcher at Brookhaven Lab now working for the University of North Carolina. "Certain methods can visualize the plaque load, or overall number of plaques, which plays a role in clinical assessment and analysis of drug efficacy. But these methods cannot provide the resolution needed to show us the properties of individual A plaques."

A technique
'/>"/>

Contact: Kendra Snyder
ksnyder@bnl.gov
631-344-8191
DOE/Brookhaven National Laboratory
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. X-rays power discoveries at Chicagos Field Museum
2. X-rays often repeated for patients in developing countries
3. Possible link found between X-rays and prostate cancer
4. X-Rays Help Predict Permanent Bone Damage From Bisphosphonates
5. Pot bellies linked to early signs of cardiovascular disease
6. Eye-staining technique offers early detection for dry eye syndrome
7. Early Weight Loss in Women Linked to Dementia
8. Isolation of a new gene family essential for early development
9. U of M study: Early treatment can reverse heart damage
10. Gerresheimer to be Included in the SDAX Early Decision on Inclusion in the MDAX on September 5, 2007
11. Rock N Roll: Sex, Drugs and an Early Exit
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... July 29, 2014 Many people complain about ... they do each morning is put on glasses to see ... These same individuals also may be dissatisfied with their vision ... , Cataracts may cause difficulty driving, especially at night due ... or find one’s golf ball, see the TV, sew or ...
(Date:7/29/2014)... HealthDay Reporter TUESDAY, July 29, 2014 ... a single dose of the hormone oxytocin quickly improved their ... Known as the "love hormone," oxytocin has been shown ... between mothers and their children. In this study, it ... brain that has long been associated with the processing of ...
(Date:7/29/2014)... (PRWEB) July 29, 2014 During his 37 ... Bruce, DMD & Associates, has had a steady stream of ... dentistry. These students have now gone on to dental school ... proving that the shadowing program helps college students find success. ... Bruce has given them the chance to see a realistic ...
(Date:7/29/2014)... that helps headache sufferers to record the severity and ... of a Griffith research study. , A new approach ... at coping with their triggers and is being led ... Basis of Health program. , He has developed an ... triggers of their headaches called Learning to Cope with ...
(Date:7/29/2014)... West Palm Beach, Florida (PRWEB) July 29, 2014 ... a new scholarship for law students this week. The scholarship ... rights of abused children and their families. , Steinger, Iscoe ... move past abuse, and want tomorrow’s attorneys to do the ... United States each year according to the nonprofit Childhelp ...
Breaking Medicine News(10 mins):Health News:Cataract Surgery: New Technology for Reduced Dependence on Glasses 2Health News:'Love Hormone' Oxytocin May Help Some With Autism 2Health News:'Love Hormone' Oxytocin May Help Some With Autism 3Health News:Arthur Bruce Dental Helps College Students 2Health News:Steinger, Iscoe & Greene Offers Child Advocate Scholarship 2
... the growing number of HIV infected individuals, India plans to ... in the country to // teach others about safe sex ... be weavers, or agricultural laborers or just be hanging around ... India's National Aids Control Organization "But the point is the ...
... have identified several factors that are linked with an ... among adolescents// with long-QT syndrome (an abnormality of the ... specific finding on the ECG), according to a study. ... cardiac arrest (when an episode of cardiac arrest is ...
... who use inhaled corticosteroids may have a significantly ... study published in the September issue of CHEST, ... Chest Physicians (ACCP). New research shows that patients ... hospital discharge had a 25 percent reduced all-cause ...
... attitude towards using insect repellent, eventually proved to be the cause ... Nile virus. ,He died on Sept. 3 ... since 2002, when four county residents - all older than 60 ... ,Boggs' wife of 66 years, Mary Boggs, said that ...
... officials have announced a hike of 5.6 percent for ... premiums for the wealthier// beneficiaries will increase by 83 ... has required the affluent to pay more. ,Mark ... Medicaid Services said that the standard monthly premium for ...
... there has been a significant reduction in the risk of deaths ... , A 25 % reduction in the risk of fatal cardiovascular ... people. However, British heart experts feel that these benefits may be ... healthier than the diet in the west. ,The findings ...
Cached Medicine News:Health News:Factors Associated With Increased Risk of Cardiac Arrest For Adolescents 2Health News:Inhaled Corticosteroids Reduce Death in Patients with COPD 2Health News:91-year-old city man Falls Victim to West Nile Virus 2Health News:Medicare Premiums to be Higher Next Year 2Health News:Live long with Green tea!! 2Health News:Live long with Green tea!! 3
(Date:7/29/2014)... July 29, 2014 McGraw-Hill Education Professional, a ... science, technical, and medical communities, has announced the launch ... mobile application of the world-renowned medical education platform. ... AccessMedicine App , available for download onto all iOS ... able to gain access to valuable AccessMedicine ...
(Date:7/29/2014)... Mass. , July 29, 2014  Instrumentation Laboratory (IL) ... including a new corporate logo. This is part of a ... Founded in Boston, MA , ... family of companies since 1992.  Other companies in the group ... Biokit and Systelab ( Barcelona, Spain ).  Like ...
(Date:7/29/2014)... 2014  Based on its recent analysis of ... & Sullivan recognizes MobileHelp with the 2014 North ... Value Leadership. MobileHelp,s leadership in flexibility across in-home ... progression in personal emergency response, and exemplifies key ... MobileHelp is at the forefront of convenience ...
Breaking Medicine Technology:McGraw-Hill Education Professional's AccessMedicine App Delivers Instant Access to Essential Diagnostic Tools 2McGraw-Hill Education Professional's AccessMedicine App Delivers Instant Access to Essential Diagnostic Tools 3Instrumentation Laboratory Unveils New Corporate Brand 2Instrumentation Laboratory Unveils New Corporate Brand 3Frost & Sullivan Applauds MobileHelp for its Targeted Supplies for the PERS Market 2Frost & Sullivan Applauds MobileHelp for its Targeted Supplies for the PERS Market 3
... 2007 - Elixir,Pharmaceuticals, Inc., announced today new ... method for regulating,metabolism, decreasing body weight and ... poster sessions during ENDO 07, The,Endocrine Society's ... Elixir is focused on the development of ...
... - Metabasis Therapeutics,Inc. (Nasdaq:MBRX), a biopharmaceutical company ... novel drugs for the,treatment of metabolic and ... the liver and liver pathways, announced,today that ... Society's,89th Annual Meeting in Toronto, Canada., Both ...
Cached Medicine Technology:Elixir Pharmaceuticals Presents Additional Preclinical Data,Demonstrating the Potential of Ghrelin Antagonism to Regulate,Metabolism, Body Weight and Glycemic Control 2Elixir Pharmaceuticals Presents Additional Preclinical Data,Demonstrating the Potential of Ghrelin Antagonism to Regulate,Metabolism, Body Weight and Glycemic Control 3Elixir Pharmaceuticals Presents Additional Preclinical Data,Demonstrating the Potential of Ghrelin Antagonism to Regulate,Metabolism, Body Weight and Glycemic Control 4Metabasis Therapeutics Presents Results of Preclinical Studies for,MB07811, Its Novel Product Candidate for the Treatment of,Hyperlipidemia, at the Endocrine Society's Annual Meeting 2Metabasis Therapeutics Presents Results of Preclinical Studies for,MB07811, Its Novel Product Candidate for the Treatment of,Hyperlipidemia, at the Endocrine Society's Annual Meeting 3Metabasis Therapeutics Presents Results of Preclinical Studies for,MB07811, Its Novel Product Candidate for the Treatment of,Hyperlipidemia, at the Endocrine Society's Annual Meeting 4
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: