Navigation Links
Wound-Healing Maggots Succumb to Deadly Bacteria

Germs can undermine unorthodox but effective treatment, experts say

FRIDAY, Feb. 5 (HealthDay News) -- Maggots used to treat chronic wounds can be killed by a type of bacteria that infects the wounds, Danish researchers say.

Use of maggots to disinfect wounds (maggot debridement therapy) is standard procedure at wound care centers worldwide. The maggots consume dead tissue and ingest bacteria that are killed in the gut. In addition, the maggots secrete antimicrobial compounds into the wound that reduce inflammation and promote healing.

This study found that maggots applied to simulated wounds that were heavily infected with Pseudomonas aeruginosa bacteria weren't able to treat the wound and died within 20 hours.

P. aeruginosa -- which causes many hospital-acquired infections -- is often associated with chronic wounds in which bacteria clump together to form biofilms. Bacteria in biofilms have a "communication system" called quorum sensing (QS) that makes them more resistant to the patient's immune system and antibiotics.

"When we blocked the QS signaling pathways in the bacteria, the maggots were much better at surviving and potentially cleansing the wounds," study leader Dr. Anders Schou Andersen said in a news release from the Society for General Microbiology.

The findings, published Feb. 5 in the journal Microbiology, could lead to more effective treatment of wounds and new types of antibiotics, the researchers said.

"If we can find the specific bacterial mechanism that kills the maggots, we could target this when developing new treatments. For example, wounds infected with P. aeruginosa could be treated with an agent that interrupts bacterial signaling to ensure the success of maggot therapy and thereby wound healing," Andersen said.

More information

The Department of Medical Entomology at the University of Sydney and Westmead Hospital in Australia has more about maggot debridement therapy.

-- Robert Preidt

SOURCE: Society for General Microbiology, news release, Feb. 5, 2010

Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Key to Wound-Healing May Be Explained in Fish Tail
2. Medicare to consider public opinion about medical maggots
3. Maggots as Good as Gel in Leg Ulcer Treatments
4. Hero Police Dog Succumbs to Cancer - Morris Animal Foundation Honors Rocky - Also Honored Rocky Six Years Ago When He Was Shot
5. MRSA May Succumb to Honey
6. Scientists Probe Sepsis Deadly Secrets
7. HIV denialists spread misinformation online -- consequences could be deadly; and more
8. Greeks get space-based help in wake of deadly fires
9. Jefferson scientists find protein may be key in developing deadly form of pancreatic cancer
10. Drug combination might offer hope for patients deadly brain tumors
11. MARCOR Responds to Deadly MRSA Outbreak
Post Your Comments:
(Date:11/25/2015)... ... , ... Beddit® has launched a new Android app for use ... a more intuitive SleepScore™ that rates sleep quality on a 100-point scale and makes ... by a proprietary algorithm. Beddit analyzes the data to provide an easy to understand ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... provide scholarships for people struggling with eating disorders as a result of the ... second annual event, held at Fox Run Golf Club in Eureka, will help ...
(Date:11/25/2015)... ... 2015 , ... Many people know of the common symptoms of low thyroid ... skin. But many people who find their cholesterol levels and weight are creeping up ... especially if they don’t have any of the other symptoms. , Thyroid hormone plays ...
(Date:11/24/2015)... ... 2015 , ... Genesis Chiropractic Software helps practice owners automate ... between the practice owner and the patient that automatically manages all five aspects ... Click here to learn more. , According to Dr. Brian ...
(Date:11/24/2015)... Dallas, Texas (PRWEB) , ... November 24, 2015 , ... ... of all charitable donations are made in the last five weeks of the year ... #GivingTuesday was created in 2012 to connect the nation’s charities with those individuals who ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... FRANCISCO , Nov. 24, 2015  Thanks to ... Dignity Health St. Mary,s Medical Center,s Sister Diane Grassilli ... breast imaging capabilities in San Francisco ... an anonymous friend, stepped forward with a gift of ... for Breast Digital Mammography with Tomosynthesis and Whole Breast ...
(Date:11/24/2015)... Colo. , Nov. 24, 2015  Array ... that its Chief Executive Officer, Ron Squarer ... Healthcare Conference in New York.  The public is ... webcast on the Array BioPharma website.Event:Piper Jaffray Annual ... , Wednesday, December 2, 2015Time:1:30 p.m. Eastern Time ...
(Date:11/24/2015)... HOUSTON, TX and VANCOUVER, Nov. 24, 2015 /PRNewswire/ ... EPI; NASDAQ: EPIX ) announced today that the ... clinical study of EPI-506 as a treatment for metastatic ... States and Canada.  --> ... --> In the Phase 1/2 clinical trial, ...
Breaking Medicine Technology: