Navigation Links
Wound-Healing Maggots Succumb to Deadly Bacteria
Date:2/5/2010

Germs can undermine unorthodox but effective treatment, experts say

FRIDAY, Feb. 5 (HealthDay News) -- Maggots used to treat chronic wounds can be killed by a type of bacteria that infects the wounds, Danish researchers say.

Use of maggots to disinfect wounds (maggot debridement therapy) is standard procedure at wound care centers worldwide. The maggots consume dead tissue and ingest bacteria that are killed in the gut. In addition, the maggots secrete antimicrobial compounds into the wound that reduce inflammation and promote healing.

This study found that maggots applied to simulated wounds that were heavily infected with Pseudomonas aeruginosa bacteria weren't able to treat the wound and died within 20 hours.

P. aeruginosa -- which causes many hospital-acquired infections -- is often associated with chronic wounds in which bacteria clump together to form biofilms. Bacteria in biofilms have a "communication system" called quorum sensing (QS) that makes them more resistant to the patient's immune system and antibiotics.

"When we blocked the QS signaling pathways in the bacteria, the maggots were much better at surviving and potentially cleansing the wounds," study leader Dr. Anders Schou Andersen said in a news release from the Society for General Microbiology.

The findings, published Feb. 5 in the journal Microbiology, could lead to more effective treatment of wounds and new types of antibiotics, the researchers said.

"If we can find the specific bacterial mechanism that kills the maggots, we could target this when developing new treatments. For example, wounds infected with P. aeruginosa could be treated with an agent that interrupts bacterial signaling to ensure the success of maggot therapy and thereby wound healing," Andersen said.

More information

The Department of Medical Entomology at the University of Sydney and Westmead Hospital in Australia has more about maggot debridement therapy.



-- Robert Preidt



SOURCE: Society for General Microbiology, news release, Feb. 5, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Key to Wound-Healing May Be Explained in Fish Tail
2. Medicare to consider public opinion about medical maggots
3. Maggots as Good as Gel in Leg Ulcer Treatments
4. Hero Police Dog Succumbs to Cancer - Morris Animal Foundation Honors Rocky - Also Honored Rocky Six Years Ago When He Was Shot
5. MRSA May Succumb to Honey
6. Scientists Probe Sepsis Deadly Secrets
7. HIV denialists spread misinformation online -- consequences could be deadly; and more
8. Greeks get space-based help in wake of deadly fires
9. Jefferson scientists find protein may be key in developing deadly form of pancreatic cancer
10. Drug combination might offer hope for patients deadly brain tumors
11. MARCOR Responds to Deadly MRSA Outbreak
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/20/2017)... ... September 20, 2017 , ... ... Excellence (CoE) with the latest Artificial Intelligence (AI) thinking, announced today the launch ... and easy access to essential information that offers a more comprehensive understanding of ...
(Date:9/20/2017)... ... September 20, 2017 , ... Renal ... for people who have kidney disease. The theme “Describe a positive decision that ... Entrants needed to meet only one qualification— to have been diagnosed with ...
(Date:9/20/2017)... Houston, TX (PRWEB) , ... September 20, 2017 ... ... the date of the much-anticipated fall event , Look Awesome This Autumn ... demonstrations, personalized consultations, special pricing and refreshments. , Mirror Mirror Beauty Boutique ...
(Date:9/20/2017)... ... September 20, 2017 , ... As part of ... recently unveiled a redesigned website. The new site – still located at ... architects, contractors and other industry users that Garland serves. , After an ambitious ...
(Date:9/20/2017)... ... September 20, 2017 , ... In just a short time since going on ... positive feedback from customers trying the product for the first time, and others who ... developed by neurosurgeon Shawn Moore, MD, for everyone from athletes at risk from multiple ...
Breaking Medicine News(10 mins):
(Date:9/6/2017)... Eli Lilly and Company (NYSE: ... for galcanezumab and lasmiditan, two investigational treatments for migraine, ... (IHC) taking place Sept. 7-10 in Vancouver ... long-term data from an open-label study evaluating the safety ... and 240 mg) for the prevention of migraine. Galcanezumab ...
(Date:9/5/2017)... LONDON , Sept. 5, 2017  Just 18 ... Valid Insight is pleased to announce the appointment of ... Tammy Wynne , Dominic Jones-Phillips and ... from industry. ... a team of market access writers. She has over ...
(Date:9/1/2017)... Sept. 1, 2017  Bayer will present the latest research ... for Medical Oncology (ESMO) 2017 Congress, September 8-12 in ... new preclinical and clinical data on Bayer,s marketed portfolio and ... projects. "We value ... in cancer research at ESMO," said Carsten Brunn , ...
Breaking Medicine Technology: