Navigation Links
Wound-Healing Maggots Succumb to Deadly Bacteria
Date:2/5/2010

Germs can undermine unorthodox but effective treatment, experts say

FRIDAY, Feb. 5 (HealthDay News) -- Maggots used to treat chronic wounds can be killed by a type of bacteria that infects the wounds, Danish researchers say.

Use of maggots to disinfect wounds (maggot debridement therapy) is standard procedure at wound care centers worldwide. The maggots consume dead tissue and ingest bacteria that are killed in the gut. In addition, the maggots secrete antimicrobial compounds into the wound that reduce inflammation and promote healing.

This study found that maggots applied to simulated wounds that were heavily infected with Pseudomonas aeruginosa bacteria weren't able to treat the wound and died within 20 hours.

P. aeruginosa -- which causes many hospital-acquired infections -- is often associated with chronic wounds in which bacteria clump together to form biofilms. Bacteria in biofilms have a "communication system" called quorum sensing (QS) that makes them more resistant to the patient's immune system and antibiotics.

"When we blocked the QS signaling pathways in the bacteria, the maggots were much better at surviving and potentially cleansing the wounds," study leader Dr. Anders Schou Andersen said in a news release from the Society for General Microbiology.

The findings, published Feb. 5 in the journal Microbiology, could lead to more effective treatment of wounds and new types of antibiotics, the researchers said.

"If we can find the specific bacterial mechanism that kills the maggots, we could target this when developing new treatments. For example, wounds infected with P. aeruginosa could be treated with an agent that interrupts bacterial signaling to ensure the success of maggot therapy and thereby wound healing," Andersen said.

More information

The Department of Medical Entomology at the University of Sydney and Westmead Hospital in Australia has more about maggot debridement therapy.



-- Robert Preidt



SOURCE: Society for General Microbiology, news release, Feb. 5, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Key to Wound-Healing May Be Explained in Fish Tail
2. Medicare to consider public opinion about medical maggots
3. Maggots as Good as Gel in Leg Ulcer Treatments
4. Hero Police Dog Succumbs to Cancer - Morris Animal Foundation Honors Rocky - Also Honored Rocky Six Years Ago When He Was Shot
5. MRSA May Succumb to Honey
6. Scientists Probe Sepsis Deadly Secrets
7. HIV denialists spread misinformation online -- consequences could be deadly; and more
8. Greeks get space-based help in wake of deadly fires
9. Jefferson scientists find protein may be key in developing deadly form of pancreatic cancer
10. Drug combination might offer hope for patients deadly brain tumors
11. MARCOR Responds to Deadly MRSA Outbreak
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... , ... First Choice Emergency Room , the largest network of independent ... Director of its new Mesquite-Samuell Farm facility. , “We are pleased to announce ... Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van ... Wellness at Work award to iHire in recognition of their exemplary accomplishments in worksite ... 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum ...
(Date:6/24/2016)... ... 2016 , ... Those who have experienced traumatic events may suffer from a ... such as drug or alcohol abuse, as a coping mechanism. To avoid this pain ... following a traumatic event. , Trauma sufferers tend to feel a range of emotions, ...
(Date:6/24/2016)... Dallas, Texas (PRWEB) , ... June 24, 2016 ... ... 12th International Conference and Scientific Sessions in Dallas that it will receive two ... Announcement of the grants came as PHA marked its 25th anniversary by recognizing ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016 Research and Markets ... for Companion Diagnostic Tests" report to their offering. ... Companion Diagnostics The World Market for Companion ... medicine diagnostics. Market analysis in the report includes the following: ... (In Vitro Diagnostic Kits) by Region (N. America, EU, ROW), ...
(Date:6/24/2016)... KNOXVILLE, Tenn. , June 24, 2016 /PRNewswire/ ... market providing less invasive and more durable cerebrospinal ... million in funding.  The Series-A funding is led ... the Lighthouse Fund, and other private investors.  Arkis, ... less-invasive neurosurgical instrumentation and the market release of ...
(Date:6/23/2016)... Research and Markets has announced the addition ... Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality (Filler, Binder, ... Forecast to 2021" report to their offering. ... excipients market is projected to reach USD 8.1 Billion ... forecast period 2016 to 2021. The ...
Breaking Medicine Technology: