Navigation Links
Worse breast cancer outcomes for women from poorer backgrounds are not due to late diagnosis alone
Date:3/24/2010

This release is available in Spanish.

Barcelona, Spain: The largest study in Europe to look at the link between socioeconomic status and survival after breast cancer has found that women from poorer backgrounds have worse outcomes and that this is only partly explained by more advanced cancer at diagnosis.

Although other studies have found that lower socioeconomic status is linked with women consulting their doctors at a later stage when their cancer is more advanced, this is the first study to show that there may be other factors at work that mean these women are more likely to die from their disease.

Dr Esther Bastiaannet, an epidemiologist at Leiden University Medical Centre (Leiden, The Netherlands), will tell the seventh European Breast Cancer Conference (EBCC7) in Barcelona today (Wednesday), that the study included 127,599 women who were diagnosed with breast cancer between 1995 and 2005 in The Netherlands. Data from these women were linked with data from the Netherlands Institute for Social Research, which keeps records of socioeconomic status by postcode.

Dr Bastiaannet and her colleagues found that not only was there an association between tumour size at diagnosis and socioeconomic status, but also, even after adjusting for factors such as age, grade and stage of the tumour, year of diagnosis and treatment, there was still a statistically significant association between survival and socioeconomic status. Women from the poorest backgrounds were a fifth more likely to die within ten years of diagnosis than women from the wealthiest backgrounds.

Both the overall survival (deaths due to any cause) and relative survival (the ratio between the survival from breast cancer when compared to the survival expected, based on the general population) declined with lower socioeconomic status. Ten years after diagnosis, overall survival was 65% for highest socioeconomic status patients versus 58% for lowest socioeconomic status patients; relative survival was 79% for the highest socioeconomic status patients, versus 74% for the lowest socioeconomic status patients.

"An increase of five percent in relative survival [from 74-79%] may look small, but these differences are significant to the prognosis of patients with breast cancer," said Dr Bastiaannet. "The differences were statistically significant, even after adjustment for age, year of diagnosis, grade and stage of the tumour and treatment. The increased risk of death for the lowest socioeconomic status group was a fifth higher when compared to the risk for the highest socioeconomic status group.

"We concluded that socioeconomic differences in The Netherlands were associated not only with tumour size at diagnosis and but also with long term survival. The more advanced cancer at diagnosis in patients with a lower socioeconomic status only partly explains their decreased survival after five and ten years. We think further research is needed to identify reasons for these disparities, with the hope of eliminating them in the future. In addition, socioeconomic status should be considered as a prognostic factor for breast cancer patients in The Netherlands."

She said this was the largest study in Europe to look at the association between socioeconomic status and survival and the first to describe the disparities at a national level in The Netherlands. "I think that it is possible to extrapolate our findings to other countries in Europe that have similar healthcare systems to The Netherlands where healthcare is at a high level and available to everyone."

At present, it is not known for certain what factors might be contributing to the higher risk of death from breast cancer among women from poorer backgrounds. "Lifestyle factors, such as smoking, may play a role," said Dr Bastiaannet. "Access to early detection, treatment that could be influenced by other health problems, and other, as yet, unknown factors all may be involved as well."

The researchers are planning to extend their research by comparing treatment according to tumour stage, and by investigating the factors that could influence the choice of treatment.


'/>"/>

Contact: Mary Rice
mary@mrcommunication.org
ECCO-the European CanCer Organisation
Source:Eurekalert

Related medicine news :

1. Meth Exposure May Be Worse for Fetus Than Alcohol
2. Plaque on CT scan is strong predictor of heart disease, worse long-term outcomes
3. News brief: ALDH associated with worse overall survival in patients with pancreatic adenocarcinoma
4. Too Little Vitamin D May Worsen Asthma
5. Asian Air May Be Worsening Ozone Over U.S.
6. Current Smoking Can Worsen Lung Cancer
7. Obstructive sleep apnea may worsen diabetes
8. Study explains why light worsens migraine headaches
9. Allergens Worsen Sinusitis
10. Immune cell activity linked to worsening COPD
11. Study finds significantly worse outcomes in cancer patients with cognitive impairment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article ... people are unfamiliar with. The article goes on to state that individuals are now ... of these less common operations such as calf and cheek reduction. The Los Angeles ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, ... at his family verbally and physically. , “When something upset him, he couldn’t control his ... it. He would throw rocks at my other children and say he was going to ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their pencils ... an essay contest in which patients and their families pay tribute to a genetic ... 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® ... Group (TGIG), has initiated cultivation and processing operations at its production facility, and ... Nevada. , Puradigm is the manufacturer of a complete system of proactive air ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Research and ... News Issue 52" report to their offering. ... influenza treatment creates a favourable commercial environment for MedImmune to ... patient base that will serve to drive considerable growth for ... would serve to cap sales considerably, but development is still ...
(Date:6/23/2016)... NORTHBROOK, Ill. and BOGOTA, Colombia , June 23, 2016  Astellas today announced the ... joins Astellas Farma Brasil as the company,s second affiliate in Latin America . ... ... appointed General Manager of Astellas Farma Colombia ... ...
(Date:6/23/2016)... Research and Markets has announced ... Analysis (United States, China, Japan, Brazil, United Kingdom, Germany, ... offering. Surgical Procedure ... planners, provides surgical procedure volume data in a geographic ... in-depth analysis of growth drivers and inhibitors, including world ...
Breaking Medicine Technology: