Navigation Links
Worms Reveal More of Longevity's Secrets
Date:4/16/2009

The way cells use oxygen could keep them younger, longer

THURSDAY, April 16 (HealthDay News) -- Worms are providing scientists with new insights into how cells and tissues may stay youthful over the long term.

A protective mechanism used by cells to stay alive when oxygen levels are low (called a hypoxic response) promotes longevity and helps defend against some age-related diseases, a new study finds.

"This is a completely new pathway for aging and age-associated disease," senior author Dr. Matt Kaeberlein, an assistant professor of pathology at the University of Washington, Seattle, said in a university news release.

His team found that nematode worms live longer if they're also able to switch on the hypoxic response when oxygen levels are normal. In addition, the worms' cells contain fewer toxic proteins that might accumulate and clump together as they age.

The study is in the April 16 issue of the journal Science.

Buildups of toxic protein occur in the brain cells of people with Alzheimer's disease, Huntington's disease and a number of other degenerative conditions seen in the elderly, the researchers noted. Learning more about the cellular mechanisms that prevent accumulation of toxic proteins could help researchers find new treatments for these age-related diseases.

"The (study) findings suggest that hypoxic response promotes longevity and reduces the accumulation of toxic proteins by a mechanism that is distinct from both dietary restriction and insulin-like signaling. It appears to be an alternative pathway," Kaeberlein said.

"However, we don't know if future studies might reveal that all of these different genetic pathways converge somewhere down the line into a common mechanism for delaying the effects of age," he added.

The key factor that controls hypoxic response is called HIF, and the UW researchers are now trying to determine how HIF protects t
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Hookworms in MS trial
2. Ben-Gurion University of the Negev initiates project to eliminate intestinal worms in Ethiopia
3. Warmer Weather Reminds Cat Owners to Protect Against Worms
4. UC San Diego researchers target tumors with tiny nanoworms
5. Iron banded worms drying out of blood could be linked to Parkinsons and Alzheimers
6. CDC Reports Prevalence of Worms Transmitted by Dogs and Cats to Humans is Higher Than Previously Understood
7. Study Reveals How Salmonella Hijacks Cells
8. Generic Pharmaceuticals Offer Exciting Growth Opportunities in Tanzania, Reveals Frost & Sullivan
9. UCSF, Stanford Study Reveals Neural Networks Targeted in Brain Diseases
10. Brain Scans Reveal Secrets of Writers Cramp
11. National Survey Reveals Gap in Uncontrolled Asthma Knowledge - Putting Asthma Patients at Risk for Serious Health Consequences
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Worms Reveal More of Longevity's Secrets
(Date:1/22/2015)... York, New York (PRWEB) January 22, 2015 ... filed after Fresenius Medical Care recalled its GranuFlo and ... federal multidistrict litigation underway in U.S. District Court, District ... Order dated January 20th, the Court has remanded a ...
(Date:1/22/2015)... January 22, 2015 Joan Lunden, award-winning ... speaker at the upcoming 32nd Annual Miami Breast ... Physicians’ Education Resource®, LLC (PER®) , shares that “a ... gone undetected if she had not followed up her ...
(Date:1/22/2015)... January 22, 2015 IsoComforter, Inc. has introduced ... with patented IsoTube design to treat specific body parts and ... most progressive and easy to use patented cold therapy machine ... sports related orthopedic and muscle injuries. IsoComforter has become ...
(Date:1/22/2015)... 2015 As interest in the value of ... momentum worldwide, Rev. Eric J. Hall , president and ... (HCCN), will be the keynote speaker on January 27 at ... health system. , The conference, “Hope and Resilience: Innovative and ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Step into ... at the Science Museum of Virginia. Wicked Plants, the ... Wicked Plants unearths 75 poisonous, carnivorous and diabolical plants ... each room to uncover the biochemical, physical and neurological ...
Breaking Medicine News(10 mins):Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3Health News:Wicked Plants are taking over the Science Museum of Virginia 2
... Campaign for Cancer Prevention (CCP) began in,2007 with the ... care about preventing cancer. It has now,grown to a ... initiative on the social media,platform, Causes.com. Nearly five years ... Women,s,Hospital (BWH), a Harvard Medical School flagship teaching hospital, ...
... male breast cancer is low and most men do not even ... new research from the University of Leeds. Breast cancer ... diagnoses in women in the UK each year. However around 340 ... cancer each year and around 70 men will die. Funded ...
... WASHINGTON, Oct. 3In a feat of technology tweaking that ... University of California, Davis has transformed everyday iPhones into ... cost about as much as a typical app, the ... to perform detailed microscopy and spectroscopy. The team ...
... the University of Bristol, has found that children who are ... more filling. This finding, published (online ahead of print) in ... because it reveals one way in which children over-consume snack ... are at risk of obesity due to consumption of energy-rich ...
... HealthDay Reporter , FRIDAY, Sept. 30 (HealthDay News) ... effective as psychiatric drugs in reducing the agitation that ... suggests. In a three-month period, nursing home residents ... involving music, mime and humorous props showed a significant ...
... accepted for publication in The Endocrine Society,s Journal ... shift work at a young age is associated ... Previous studies have shown that long-term elevated cortisol ... and cardiovascular risk. Shift work, defined as ...
Cached Medicine News:Health News:Campaign for Cancer Prevention connects 6 million+ members on Facebook Causes to research at BWH 2Health News:Campaign for Cancer Prevention connects 6 million+ members on Facebook Causes to research at BWH 3Health News:Researchers call for more awareness of male breast cancer as cases rise 2Health News:Researchers call for more awareness of male breast cancer as cases rise 3Health News:Researchers transform iPhone into high-quality medical imaging device 2Health News:Researchers transform iPhone into high-quality medical imaging device 3Health News:Researchers transform iPhone into high-quality medical imaging device 4Health News:New study finds familiarity increases the fullness that children expect from snack foods 2Health News:Laughter Might Be Good Medicine for Alzheimer's Patients 2Health News:Laughter Might Be Good Medicine for Alzheimer's Patients 3
(Date:1/23/2015)... MERIDIAN, Idaho , Jan. 23, 2015  Now available ... Patent No. 7,849,611) support that prevents ankle sprains by ... a brace, it fits securely around the outside of ... ankle mobility & comfort while still offering protection against ...
(Date:1/23/2015)... Cord Blood America, Inc. ( www.cordblood-america.com ) (OTC Bulletin Board: ... Preliminary Proxy Statement, Schedule 14A, with the U.S. Securities & ... for shareholders detailing why a "YES" vote to increase the ... As we reflect upon the 2014 fiscal year ...
(Date:1/23/2015)... , Jan. 23, 2015  Mallinckrodt plc (NYSE: ... has approved a share repurchase program. The open-ended authorization ... of Mallinckrodt plc ordinary shares. "Funding ... top priorities as we continue to pursue a range ...
Breaking Medicine Technology:The Armor1 Ankle Roll Guard is the New Breakthrough Solution for Ankle Sprain Prevention! 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 3Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 4Mallinckrodt plc Announces Share Repurchase Program 2Mallinckrodt plc Announces Share Repurchase Program 3Mallinckrodt plc Announces Share Repurchase Program 4
... May 1, 2012 /PRNewswire-Asia-FirstCall/ -- ShangPharma Corporation (NYSE: ... leading China-based pharmaceutical and biotechnology research and development ... its annual report on Form 20-F for the ... States Securities and Exchange Commission (the "SEC"). The ...
... 2012 Jazz Pharmaceuticals plc (Nasdaq: JAZZ ) ... live webcast on Tuesday, May 8, 2012 at 4:30 p.m. ... a business and financial update and review first quarter 2012 ... be accessed from the Investors section of the Jazz Pharmaceuticals ...
Cached Medicine Technology:ShangPharma Corporation Files 2011 Annual Report on Form 20-F 2
... Anatomic Knee system was designed to ... all articulating surfaces, to minimize contact ... achieve a well balanced knee with ... The MJS Knee system allows maximum ...
... of digital mobile imaging just got ... software and instrumentation. Now using,your C-arm ... Easily Add Visualization and Navigation ... Accelerate Intraoperative Decision Making, Provide ...
... GE's surgical navigation for ... system to integrate C-arm ... technology. It features automatic ... image to the patient's ...
... on over 20 years of CT engineering ... is at the forefront of the revolution ... acquire volumetric data at high speed with ... based on extensive clinical experience and close ...
Medicine Products: