Navigation Links
Worms Control Lifespan at High Temperatures, UCSF Study Finds
Date:4/16/2009

d aging.
Humans and other warm-blooded animals have a mechanism that enables us to maintain a constant temperature as our environment heats up or cools. Kenyon said most textbooks explain that worms and other ectotherms cannot do that.

“It’s true that worms don’t regulate their body temperature, but they do regulate their response to high temperature, slowing down processes that would otherwise go much faster. In fact, they even use steroid hormones to do this, just as we do to regulate our temperature,” she said, noting that this might have been a very early evolutionary link between cold- and warm-blooded animals.

C. elegans has been known to have thermosensory or heat-sensing neurons, which allow the worms to move towards temperatures they associate with food. If the “chemical reaction” theory were accurate, worms at a constant hotter temperature would age at the same fast rate, whether their thermosensory neurons perceived the heat or not.

The researchers found that when they either killed the heat-sensing neurons or deactivated the worm’s genes that produce steroids, the worms had an even greater response to the heat, and as a result aged and died much faster than their counterparts with active neurons. The authors conclude that these heat-sensing neurons actually help the worm regulate its response to increasing heat.

The data suggest that these thermosensory neurons affect lifespan at warm temperature by changing the activity of a steroid signaling pathway, which in turn affects longevity, according to the paper. Specifically, the authors suggest that at high temperature, the worm’s thermosensory neurons produce a signal that stimulates expression of the daf-9 gene, which produces a steroid hormone that extends lifespan.

The researchers propose that this thermosensory system allows C. elegans to reduce the effect that warm temperature would otherwise have on t
'/>"/>

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved

Page: 1 2 3

Related medicine news :

1. CDC Reports Prevalence of Worms Transmitted by Dogs and Cats to Humans is Higher Than Previously Understood
2. Iron banded worms drying out of blood could be linked to Parkinsons and Alzheimers
3. UC San Diego researchers target tumors with tiny nanoworms
4. Warmer Weather Reminds Cat Owners to Protect Against Worms
5. Ben-Gurion University of the Negev initiates project to eliminate intestinal worms in Ethiopia
6. Hookworms in MS trial
7. Worms Reveal More of Longevitys Secrets
8. Chromatin remodeling complex connected to DNA damage control
9. More than two-thirds of sexually active NYC youth use condoms, but other forms of birth control lag
10. New Asthma Guidelines Stress Disease Control
11. UI nursing researcher to study post-operative pain control
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... Yisrayl Hawkins, Pastor at The House of Yahweh in Abilene, ... Ferguson, Missouri unrest. Yisrayl starts his letter by showing the ... has only increased. , He continues in his letter ... is a very specific reason for mankind and covers those ... of rules, or Laws that if followed would ensure that ...
(Date:12/26/2014)... London, England (PRWEB) December 26, 2014 ... to take place March 24-28, 2015 in Rome, Italy ... years' line-up includes workshops on a wide ... insomnia, as well as peak performance training in athletes. ... from around the world. , Biofeedback monitoring allows clients ...
(Date:12/26/2014)... (PRWEB) December 26, 2014 Plugin and template ... TransPack Volume 5 Plugin for Final Cut Pro X. , ... hard light tool to pull off an industry professional look” ... get their hands on TransPack Volume 5, a new level ... is a set of over 50 Final Cut Pro X ...
(Date:12/26/2014)... 2014 “Many people become overwhelmed by ... claim issues and phone calls with insurance companies,” The ... featuring their free eBook on pedestrian and bicycle ... pedestrian and bicycle auto accident claims assures the injured ... of professionally handling their case while they focus on ...
(Date:12/26/2014)... 26, 2014 India Network Foundation, a ... the USA, announced today a new version of “ ... choosing the right plan for their visiting parents. The ... of the selection process when choosing an insurance plan ... with only a few clicks. Many elderly Asian Indian ...
Breaking Medicine News(10 mins):Health News:Yisrayl Hawkins Pleads for Peace in Ferguson and Beyond in New Open Letter 2Health News:Final Workshop Line-up Announced for 18th Annual Biofeedback Conference in Rome, Italy 2Health News:Today a new plugin was announced from Pixel Film Studios, TransPack Volume 5 for Final Cut Pro X 2Health News:Guide to Handling Pedestrian and Bicycle Accidents Released By The Jones Firm, Featured in Recent Article 2Health News:India Network Health Insurance Announces new Comprehensive Pre-existing Condition Coverage policy for Visitors to the United States 2Health News:India Network Health Insurance Announces new Comprehensive Pre-existing Condition Coverage policy for Visitors to the United States 3
... has been identified as the "signature injury" of the ... is known to cause deficits in memory, attention and ... disorder (PTSD), depression, anxiety disorders and substance abuse. , ... TBI, based on statistics gathered by the Veterans Administration,s ...
... woman receives vitamins to prevent birth defects of the brain ... link between periodontal disease and preterm and low birth weight ... oral health. Asian- and Spanish-speaking women learn the signs of ... being helped through local grants announced today by the March ...
... Recession there is at least one company making sure ... boardrooms around the nation, business leaders are sitting down ... recession on their business. Layoffs, cutbacks and downsizing ... Aegis Living (http// www.AegisLiving.com ) a national leader in ...
... can indicate whether vaginal birth would be safe, study says ... of the uterine scar from a cesarean delivery can help ... uterine rupture and may safely try to have a vaginal ... "The thicker the scar is, the stronger the scar is, ...
... Smithfield Foods, Inc. (NYSE: SFD ) announced ... with The National Breast Cancer Foundation in effort to ... Smithfield,s Lean Generation(R) Deli ( www.leangenerationdeli.com ) contributed more ... The National Breast Cancer Foundation is an extremely effective ...
... California at San Diego have come up with a ... of nanotubes and stem cells. This new finding could ... patients who undergo orthopedic surgery., In recent years, stem ... studies suggesting revolutionary medical benefits due to their ability ...
Cached Medicine News:Health News:Study of Iraq veterans' traumatic brain injuries to be conducted by UB researchers 2Health News:Seven Washington Organizations Receive Almost $126,000 Through March of Dimes Awards and Grants 2Health News:Seven Washington Organizations Receive Almost $126,000 Through March of Dimes Awards and Grants 3Health News:Seven Washington Organizations Receive Almost $126,000 Through March of Dimes Awards and Grants 4Health News:Aegis Living Focuses On Taking Care of Their Own in 2009 2Health News:Aegis Living Focuses On Taking Care of Their Own in 2009 3Health News:Using C-Section Scars to Predict Future Deliveries 2Health News:Using C-Section Scars to Predict Future Deliveries 3Health News:Smithfield Foods' Lean Generation(R) Deli Partnership with National Breast Cancer Foundation Celebrates $135,000 Contribution 2Health News:UC San Diego engineers develop novel method for accelerated bone growth 2Health News:UC San Diego engineers develop novel method for accelerated bone growth 3
(Date:12/24/2014)... Dec. 23, 2014   Synageva BioPharma Corp. ... company developing therapeutic products for rare disorders, today ... of the Marketing Authorization Application (MAA) for sebelipase ... the company,s request for accelerated assessment, which has ... time.   The MAA, and the ...
(Date:12/24/2014)... Dec. 23, 2014 Tianyin Pharmaceutical Co., ... specializes in patented biopharmaceutical, modernized traditional Chinese medicine ... today announced that the Company achieved the Public ... Practice (GMP) certificate of TPI,s Qionglai Facility (QLF) ... The public notice period is a significant procedure ...
(Date:12/22/2014)... 22, 2014  CytoSorbents Corporation (OTCQB:CTSOD), a critical ... purification technology to help fight deadly inflammation in ... worldwide, today announced the appointment of Dr. ... its Senior Vice President of Clinical Development, effective ... Di Russo is an accomplished pediatric cardiothoracic ...
Breaking Medicine Technology:Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 2Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 3TPI QLF Achieved Public Notice Status of GMP Certification 2TPI QLF Achieved Public Notice Status of GMP Certification 3CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 2CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 3CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 4CytoSorbents Appoints Dr. Gregory B. Di Russo as Senior Vice President of Clinical Development 5
... PHILADELPHIA, Pa. June 20 GlaxoSmithKline,(NYSE: GSK ... and Drug,Administration has extended the priority review period ... treated patients,with chronic idiopathic thrombocytopenic purpura, as they ... Drug User Fee action date has,been extended to ...
... OAK LAWN, Ill., June 20 Advocate Christ,Medical Center ... a few institutions,in the Chicago area, the only one ... hospitals nationally that are using a glue-like liquid for,the ... a recent two-and-a-half-hour procedure, Thomas J. Grobelny MD, of,the ...
Cached Medicine Technology:GSK Update on FDA Review of Promacta(R) (Eltrombopag) 2Advocate Christ Medical Center Using Glue-Like Liquid to Seal Off Brain Aneurysms 2
For the quantitative in vitro determination of CK-MB in serum and plasma...
For the quantitative in vitro determination of Cholesterol in serum and plasma....
For the quantitative in vitro determination of Cholesterol in serum and plasma....
For the quantitative in vitro determination of Alanine Aminotransferase (ALT) in serum and plasma....
Medicine Products: