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World's most powerful MRI ready to scan human brain
Date:12/4/2007

The world's most powerful medical magnetic resonance imaging machine, the 9.4 Tesla at the University of Illinois at Chicago, has successfully completed safety trials and may soon offer physicians a real-time view of biological processes in the human brain.

The safety study was published in the November Journal of Magnetic Resonance Imaging in an issue focused on MRI safety.

Researchers and physicians hope that the 9.4T will usher in a new era of brain imaging in which they will be able to observe metabolic processes and customize health care.

Oncologists, for example, may one day be able to tailor radiation therapy based on a brain tumor's real-time response to treatment. Currently, physicians often must wait weeks to see if a tumor is shrinking in response to therapy. With the 9.4T, it will be possible to see if individual cells within the tumor are dying long before the tumor has begun to shrink.

The 9.4T magnet has a field strength more than three times that of state-of-the-art clinical units. UIC's 9.4T is the first such device large enough to scan the head and visualize the human brain.

"Because the more powerful magnet allows us to visualize different types of molecules, we are seeing activity in the brain along a completely different dimension," said Dr. Keith Thulborn, director of UIC's Center for Magnetic Resonance Research.

Current MRI visualizes water molecules to track biochemical processes. By visualizing the sodium ions involved in those processes instead, the 9.4T permits researchers to directly follow one of the most important energy-consuming processes in the cellular machinery in the brain.

The strength of magnetic resonance scanners has increased from less than 0.5T up to the first 8T in 1998. As human safety data became available, the FDA limits were revised upwards accordingly -- to the current level of 8T in 2003.

In this safety trial, 25 healthy volunteers -- 12 m
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Contact: Jeanne Galatzer-Levy
jgala@uic.edu
312-996-1583
University of Illinois at Chicago
Source:Eurekalert

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