Navigation Links
World's first delivery of intra-arterial Avastin directly into brain tumor
Date:11/17/2009

y available treatments," says co-author and co-PI, Dr. Howard Riina, co-director of interventional neuroradiology at NewYork-Presbyterian Hospital/Weill Cornell Medical Center and associate professor of neurological surgery, neurology and radiology at Weill Cornell Medical College.

Because of the blood-brain barrier (BBB), which prevents many IV-administered drugs from penetrating the blood vessel walls sufficiently in order to get into the brain, no one knows for sure if current drugs actually get into the brain after IV infusion.

"This new technique may be a way to get through that barrier and deliver higher doses of drug to the tumor with less toxicity to the patient," says Dr. Boockvar.

To deliver the drug, neurosurgeons direct a hair-thin microcatheter through blood vessels in the body, via the carotid artery running up the neck, and then into the smaller arteries deep in the brain. Upon arriving at the tumor site, a drug to open the blood-brain barrier is injected. After the BBB is temporarily opened -- a window of time lasting approximately five minutes -- the chemotherapeutic agent Avastin is injected directly into the malignant tumor.

Participants in the trial will be given varying doses of the drug in order to test which dose is best tolerated. Following this Phase I trial, the researchers plan to immediately begin a Phase II trial to test the technique's efficacy.

"This potential new drug delivery system demonstrates translational research from the Brain and Spine Center of NewYork-Presbyterian Hospital/Weill Cornell Medical Center at its best," says Dr. Philip E. Stieg, chairman of neurological surgery at Weill Cornell Medical College and neurosurgeon-in-chief at NewYork-Presbyterian/Weill Cornell. "If proven successful, it is a promising move forward for patients dealing with resistant brain tumors."

The current standard of care is to give patients with GBM the drug bevacizumab (Avastin) intravenou
'/>"/>

Contact: John Rodgers
jdr2001@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Paging All Science and Medical Mavens: Get To Philadelphia Stat for Body Worlds and Beyond
2. BODY WORLDS Anatomical Exhibitions of Donor Bodies Receives 28 Millionth Visitor.
3. Variants of umami taste receptor contribute to our individualized flavor worlds
4. Scienceroll.com on the Medical Implications of Virtual Worlds
5. Gunther Von Hagens BODY WORLDS and KORPERWELTEN - Not Affiliated With Paris Copycat Display
6. BODY WORLDS Exhibition Uses Lung Specimens to Launch Anti-Smoking Campaign at the San Diego Natural History Museum
7. HHS AIDS.gov to Use Blogs, Virtual Worlds, and Social Networks to Deliver HIV Information for World AIDS Day 2008
8. Gunther von Hagens BODY WORLDS Exhibitions Welcome Specimens From Worlds First Living Body Donor for Plastination
9. Gunther Von Hagens BODY WORLDS Exhibitions Mark 25th Million Visitor Milestone
10. California Science Center Welcomes 1-Millionth BODY WORLDS Visitor
11. Specimens in BODY WORLDS Exhibitions Stem Primarily from German Body Donation Program
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... get more fruits and vegetables at school than they do ... is true for students from wealthier families. These findings ... a healthy boost to poor students, diets, according to the ... students all ate a similar amount of fruits and vegetables ... recently in the journal Preventive Medicine . ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, 2014 (HealthDay ... work commitment is a big reason why, new research suggests. ... Mathias Basner, an assistant professor of sleep and chronobiology in ... A time-use survey of nearly 125,000 Americans, ages 15 ... exchanged for sleep. Short sleepers -- those who slept six ...
(Date:12/15/2014)... December 15, 2014 Main Street Dental ... is weighing in on a new study providing evidence ... the oral hygiene of children. , Sufficient enough evidence ... such as pop or juice drinks, with the onset ... however, is whether drinks listed as 100% fruit juice, ...
(Date:12/15/2014)... 2014 Health Dialog, a leading ... that it has received Patient Oriented Accreditation from ... its Disease Management (DM) Programs for asthma, congestive ... heart disease and diabetes. This marks the 12th ... Dialog’s Disease Management (DM) Programs, reaffirming Health Dialog’s ...
(Date:12/15/2014)... 15, 2014 Kathy McAfee, America's Marketing ... World Awards in the category of Best Blog 2014. ... for her weekly career blog Networking Ahead ... help professionals elevate their talent and influence through better ... after her book Networking Ahead for Business, has been ...
Breaking Medicine News(10 mins):Health News:Poor Students Eat Healthier Foods at School, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:Main Street Dental Team, Unionville’s Most Innovative Dental Clinic, Comments on New Study Relating Pure Fruit Juice to Poor Oral Hygiene 2Health News:Health Dialog Receives NCQA Accreditation for Disease Management Programs 2Health News:Kathy McAfee, America’s Marketing Motivator, Wins Best Blog from Women World Awards 2
... Amerigroup Corporation (NYSE: AGP ) today announced ... Conference on November 12 in Phoenix, Arizona. , A live webcast ... p.m. Eastern Time, can be accessed on Amerigroup,s Web site, ... of the webcast will be available for 30 days after the ...
... they occur , TUESDAY, Nov. 3 (HealthDay News) -- ... they actually experience, a new study finds. , The ... assess their levels of neuroticism and depression. For the ... they felt any of 15 common physical symptoms, including ...
... stage small cell lung cancer(LSCL) with a combination of ... opening the door to larger scale investigation, according to ... Anderson Cancer Center. The Phase II study was ... the annual meeting of the American Society for Radiation ...
... Provista ... of breast cancer. , ... AZ (PRWEB) November 3, 2009 -- A healthy 44-year-old woman will celebrate many future birthdays ... cancer., , ,Dr. Sweeten, a board-certified gynecologist and Fellow of the American College of Obstetricians ...
... , RONKONKOMA, N.Y., Nov. 3 NBTY, Inc. (NYSE: NTY ... marketer of nutritional supplements, today announced it will web cast a ... web site, ( www.NBTY.com ), on Monday, November 9, ... for the fiscal fourth quarter results will be issued at 4:00 ...
... , PARK RIDGE, Ill. and CHICAGO, Nov. 3 To ... the national debate on healthcare reform, the LIFE ... be hosting a public forum on "Ethics and Healthcare Reform" ... Edison Park Lutheran Church , 6626 N. Oliphant Ave., ...
Cached Medicine News:Health News:Depression May Blur Memory of Aches and Pains 2Health News:Study of concurrent radiotherapy, chemotherapy shows promise in small cell lung cancer 2Health News:Study of concurrent radiotherapy, chemotherapy shows promise in small cell lung cancer 3Health News:A Breast Cancer Test That Saves Lives 2Health News:A Breast Cancer Test That Saves Lives 3Health News:NBTY to Web Cast Fiscal Fourth Quarter Conference Call 2Health News:Ethics and Healthcare Reform Panel, Community Forum Open to Public November 17 2Health News:Ethics and Healthcare Reform Panel, Community Forum Open to Public November 17 3
(Date:12/15/2014)... 12, 2014 Research and Markets ( ... "Inferior Vena Cava (IVC) Filters - Global Trends, Estimates ... http://photos.prnewswire.com/prnh/20130307/600769 Global ... reach US$435 million by 2016. The North ... the global value while Europe ...
(Date:12/15/2014)... BRIDGEWATER, N.J. , Dec. 15, 2014 /PRNewswire/ ... (EURONEXT: SAN and NYSE: SNY) are collaborating with nationally-recognized ... Cholesterol Counts , an awareness program that will gauge ... the risks associated with high LDL-C (bad cholesterol).  American ... to take a brief poll and answer a ...
(Date:12/15/2014)... --  DaVita HealthCare Partners Inc.  (NYSE: ... most innovative health care communities, today announced that ... Research  (DCR) and  HealthCare Partners Clinical Research , will ... research and data analytics services, specifically in patients ... disease (ESRD), as well as primary care and ...
Breaking Medicine Technology:Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 2Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 3Inferior Vena Cava (IVC) Filters - Global Trends, Estimates and Forecasts, 2012-2018 4Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 2Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 3Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 4Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 5Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 6DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 2DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 3DaVita Clinical Research and HealthCare Partners Clinical Research to Merge and Expand Clinical Trials and Data Analytics Capabilities 4
... 2011 Pharmatek Laboratories, Inc., a premier contract ... announced that it has added spray drying to ... has purchased a Buchi B-290 Mini Spray Dryer ...  This technology can be used for both oral ...
... (NASDAQ: STXS ) today announced that executive management ... The Deutsche Bank Annual Health Care Conference ... of Stereotaxis, is scheduled to present an overview of the ... The JMP Securities Annual Research Conference in San Francisco. ...
Cached Medicine Technology:Pharmatek Laboratories Adds Spray Drying to Drug Development Services 2Stereotaxis to Present at Upcoming Investor Conferences 2Stereotaxis to Present at Upcoming Investor Conferences 3
Used following hysterectomy procedure. Often attached to Bard bile bag....
Single round silicone drain with 10 in. hole pattern, 49 in. long...
Hubbed drains are made of translucent silicone and include a full-length X-ray opaque stripe....
... For Excellent Drainage PLUS Greater Patient ... BLAKE Drains are white, radiopaque silicone drains ... a solid core center. Their other components ... extension tubing and an adapter. The drains ...
Medicine Products: