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World-first high blood pressure treatment trialled in Melbourne
Date:4/3/2009

A world-first breakthrough to treat high blood pressure has been successfully trialled in Melbourne.

The clinical trial showed significant improvement in blood pressure of participants who were given a new catheter-based treatment where blood pressure lowering medication had failed.

Director of Monash University's Centre of Cardiovascular Research and Education in Therapeutics, Professor Henry Krum led the research collaboration between Monash, the Baker Heart and Diabetes Institute, and St Vincent's Hospital to develop the new surgical technique that disrupts nerves around the kidneys to dramatically reduce high blood pressure.

The technique could benefit those at high risk of heart attack or stroke from high blood pressure that resists conventional drug treatments.

Professor Krum presented these data in a late breaking clinical trial session at The American College of Cardiology's 58th Annual Scientific Session earlier this week and was lead author on a simultaneous publication in The Lancet.

The results are set to revolutionise high blood pressure treatment in patients around the world.

Professor Henry Krum said the treatment would benefit those five to twenty per cent of patients with high blood pressure who do not respond to medication.

"Patients who underwent the procedure had a significant reduction in their blood pressure levels and we were able therefore to reduce their risk of severe stroke or heart attack," Professor Krum said.

A total of 50 patients were recruited from Australia and overseas for the trial conducted by a team of researchers, which included Professor Henry Krum, from Monash University, Professor Markus Schlaich and Professor Murray Esler from Baker IDI and Professor Rob Whitbourn from St Vincent's Hospital, Melbourne.

Professor Krum said the trial results were the most significant in the treatment of high blood pressure since the introduction
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Contact: Samantha Blair
Samantha.blair@adm.monash.edu.au
61-399-034-841
Monash University
Source:Eurekalert

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