Navigation Links
Women's Testosterone Patch May Not Work
Date:3/2/2009

U.K. study also questions safety of drug Intrinsa used for sexual dysfunction

MONDAY, March 2 (HealthDay News) -- A new testosterone patch designed to boost a woman's sex drive may be ineffective, and questions remain about its long-term safety, according to the journal Drugs and Therapeutics Bulletin.

The drug Intrinsa was recently approved in the United Kingdom for treatment of women who've gone through menopause as the result of ovary and womb removal and who are receiving estrogen replacement therapy. There is some evidence that low levels of circulating testosterone may be linked to a decline in sex drive after menopause.

The patch, which is placed on the lower abdomen and delivers a daily dose of testosterone, is worn constantly and replaced twice weekly.

The journal noted, in finding that the patch may not work, that key clinical trials on testosterone patches involved highly selective groups of women. For example, the studies excluded those with various mental or physical conditions that could affect sex drive. In some trials, a hypoactive sexual desire disorder (HSDD) diagnosis was based on short, unvalidated questionnaires filled out by participants, the journal reported.

There were other problems with the studies:

  • There was a large placebo response. Significant numbers of women not treated with the patch reported improved sex drive, which suggests that low testosterone levels may not have been the problem.
  • Improvements in sex drive were small.
  • Many women were already having sex two or three times a month before they entered the trials, which raises questions about whether they really had poor sex drive in the first place.
  • The trials for Intrinsa lasted a maximum of six months, which means they didn't demonstrate the long-term safety of the patch.
  • Rates of side effects in the two key trials were around 75 percent. These included skin reactions at sites where the patches were applied, acne, excess hair, hair loss, breast pain, weight gain, insomnia , voice deepening, and migraine.

"The published evidence so far is based on highly selected women and only shows small improvements in sexual parameters and large placebo responses," according to the journal. "Also, the long-term safety of the treatment is unknown. Unwanted side effects are common and not always reversible. For all these reasons, we cannot recommend Intrinsa for use in women with sexual dysfunction."

More information

The National Women's Health Information Center has more about sexual health.



-- Robert Preidt



SOURCE: BMJ specialist journals, news release, March 3, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Womenshealthchannel Enhancements Support Pregnant Teens
2. Prostate cancer drug reduces testosterone levels in as little as 3 days
3. Study shows testosterone improves sexual well-being in post-menopausal women
4. Testosterone Patch Restores Libido in Postmenopausal Women
5. Testosterone key to disease transmission
6. AUDIO from Medialink and Solvay: Men Suffering From Symptoms of Low Testosterone Should Talk to Their Doctor
7. Studies Support Testosterone Supplements for Older Men
8. Gamma Labs to Boost Testosterone At World Series of Poker In Las Vegas
9. Men With Low Testosterone Not Receiving Treatment
10. Many men with low testosterone levels do not receive treatment
11. Testosterone Spray Improves Sexual Satisfaction in Women
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Women's Testosterone Patch May Not Work
(Date:5/4/2016)... ... May 04, 2016 , ... ... charity program created to assist the people of their local community. The agency ... organizations and community leaders. Their hope is to bring awareness to important local ...
(Date:5/4/2016)... ... ... Dr. Elyson and Dr. Assili, dentist in Northridge , announce that they ... common dental procedure, is performed for many adolescents and young adults today. While wisdom ... complications. By providing wisdom tooth removal surgery at their office, Dr. Elyson and Dr. ...
(Date:5/4/2016)... ... ... Francesca Loparco, Co-Founder of Queen City Dream Cars, an exotic car rental business ... at Christenbury Eye Center. The entrepreneur struggled with her computer, riding horses and driving ... her in-office consultation and eye exam. Francesca’s eyesight was restored to 20/20 in both ...
(Date:5/4/2016)... ... May 04, 2016 , ... Bayco ... compact tactical (6.7 inch) dual-light flashlights in models NSP-9842XL and NSR-9844XL . ... retail starting at $59.95) uses 2 included CR-123 batteries to produce up to ...
(Date:5/4/2016)... ... May 04, 2016 , ... Warren L. Smith M.D. , There ... UTIs, have plagued people since the beginning of recorded medical history, and in ... every year. It's not just a matter of inconvenience; bladder infections cost us billions ...
Breaking Medicine News(10 mins):
(Date:5/4/2016)... May 4, 2016 Valeritas Holdings, ... an alternative public offering (APO). This was accomplished via ... Valeritas, Inc. and a private placement of approximately 5 ... per share. Under the terms of the ... Valeritas Holdings, Inc. will trade on the OTC Markets ...
(Date:5/4/2016)... , May 4, 2016 ... of the  "Global Actinic Keratosis Market and ... their offering.       (Logo: ... Market and Competitive Landscape Highlights 2016, provides ... Actinic Keratosis epidemiology, Actinic Keratosis market valuations ...
(Date:5/3/2016)... 2016 Research and Markets has ... Cell Therapy Market Outlook 2020" report to their ... , ,Recombinant technology has improved significantly in past years ... developed in coming years. Many cancer drugs have been ... therapies are also expected to be developed with its ...
Breaking Medicine Technology: