Navigation Links
Women's Chromosomes May Affect Blood Pressure
Date:3/15/2010

The effect might be strongest after menopause, mouse study suggests

MONDAY, March 15 (HealthDay News) -- Scientists have believed that testosterone and estrogen play a major role in regulating blood pressure, but a new study in mice suggests that female sex chromosomes could also be key, at least after menopause begins.

In the study, researchers genetically engineered male mice to have female chromosomes (XX) and females to have male chromosomes (YY). They found that the chromosomes affected the rodents' blood pressure on their own.

"XX mice have a greater magnitude of hypertension than XY mice regardless of whether they are male or female," lead investigator Kathryn Sandberg, director of the Georgetown University Medical Center for the Study of Sex Differences in Health, Aging and Disease, said in a news release from Georgetown.

"Up until now, it has been impossible to separate the influence of sex chromosomes from the effects of sex hormones, and in this paper, we have shown for the first time that sex chromosomes are impacting blood pressure -- independent of sex hormones," she said. "That is not to say sex hormones don't matter in blood pressure regulation, because they do, but we now know they aren't the only players."

Why does this matter?

Because "there is a real jump in blood pressure and incidence of hypertension in menopausal women, and while the condition is treatable, blood pressure in many of these women is not fully under control, making them far more susceptible to cardiovascular and kidney disease and stroke," Sandberg said. "Therefore, it would be wonderful to have specific therapies that target the root cause of this hypertension."

The study appears online March 15 in the journal Hypertension.

More information:

There's more on hypertension at the U.S. National Library of Medicine.



-- Randy Dotinga



SOURCE: Georgetown University Medical Center, press release, March 15, 2010.


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Womenshealthchannel Enhancements Support Pregnant Teens
2. Infectious Virus Hides In Human Chromosomes During Latency And Can Be Passed From Parents To Their Children
3. Immune cells from patients with rheumatoid arthritis have prematurely aged chromosomes
4. Research shines spotlight on a key player in the dance of chromosomes
5. Herceptin helps women with multiple chromosomes containing HER2 gene, study finds
6. Grant Supports Study of Abnormal Ring-Shaped Chromosomes
7. Insurance status of gunshot trauma patients affects mortality outcomes
8. Research: How you think about your age may affect how you age
9. Testosterone deficiency affects male cancer survivors quality of life
10. How does religion affect psychiatric treatment?
11. Chemical tags likely to affect metabolism, cancer development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... June 27, 2016 , ... A revolution is ... emergency ambulance transport experience for the millions of people who require these medical ... the taxi industry through the use of technology. Now, SmartEMS has put forth ...
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet ... product that was developed to enhance the health of felines. The formula is all-natural ... two main herbs in the PawPaws Cat Kidney Support Supplement Soft Chews ...
(Date:6/25/2016)... ... ... The temporary closing of Bruton Memorial Library on June 21 due to a possible lice ... overlooked aspect of head lice: the parasite’s ability to live away from a human host, ... a necessary one in the event that lice have simply gotten out of control. , ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of ... recognition of their exemplary accomplishments in worksite health promotion. , The Wellness at Work ... Symposium at the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses ...
(Date:6/24/2016)... PASADENA, CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. ... he would lash out at his family verbally and physically. , “When something upset him, ... table, he would use it. He would throw rocks at my other children and say ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... ANGELES , June 23, 2016 ... CAPR ), a biotechnology company focused ... therapeutics, today announced that patient enrollment in its ... in Duchenne) has exceeded 50% of its 24-patient ... enrollment in the third quarter of 2016, and ...
(Date:6/23/2016)... and INDIANAPOLIS , June ... receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is any ... scholarship winners, announced today online at www.diabetesscholars.org ... type 1 diabetes stand in the way of academic ... supported the Foundation,s scholarship program since 2012, and continues ...
(Date:6/23/2016)... The vast majority of dialysis patients currently ... are usually 3 times a week, with treatment times ... time, equipment preparation and wait time.  This regimen can ... patients who are elderly and frail.  Many elderly dialysis ... centers for some duration of time. Residents ...
Breaking Medicine Technology: