Navigation Links
Women with rheumatoid arthritis and lupus give birth to fewer children
Date:2/16/2012

New research shows that more than half of women with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) have fewer children than desired. While patient choice has some influence on the smaller family size, findings published today in Arthritis Care & Research, a journal of the American College of Rheumatology (ACR), suggest that higher rates of infertility and miscarriage may also impact the number of offspring born to women with these chronic conditions.

According to the ACR up to 322,000 U.S. adults have systemic lupusa disease in which the body's immune system becomes overactive and attacks healthy cells, tissues, or organs. Roughly 1.3 million adult Americans suffer from RA, a chronic autoimmune disease that causes painful joint inflammation. Medical evidence reports that both RA and SLE are more common in women, and onset often occurs during reproductive years which can lead to challenges in family-building.

To further understand the role of infertility, pregnancy loss and family size choice in women with RA and SLE, Megan Clowse, M.D., Kaleb Michaud, Ph.D. and colleagues from institutes across the U.S. surveyed 1,017 female participants in the National Data Bank for Rheumatic Diseases. Respondents to the reproductive-health questionnaire included 578 women with RA and 114 with SLE, who based upon their responses, were then categorized as: those interested in having children at symptom onset who had either fewer children than planned (group A) or the same number as planned (group B), and those no longer interested in having children at diagnosis (group C).

Study findings reveal that over 60% of respondents were in group C. Researchers found that 55% of women with RA and 64% with SLE had fewer children than originally planned. Women with RA who were in group A had an infertility rate 1.5 times higher than those in group B, but both groups had similar rates of miscarriage. Women with SLE in group A had a similar number of pregnancies as those in group B, but a 3-fold higher miscarriage rate.

Overall the infertility rate among participants with RA was 42% in women who had fewer children than desired. In women diagnosed with RA during childbearing years the infertility rate was higher than in those diagnosed after childbearing was complete. For participants with SLE no significant increase in infertility was noted. However, among women with lupus having fewer children than desired was associated with pregnancy loss. The authors suggest that patient education to enhance awareness of safe medical options during pregnancy and effective control of these autoimmune diseases will assist women with achieving their childbearing goals.

"Our study highlights important reproductive-health concerns for women with RA and lupus," said Dr. Clowse. Study findings reported that concerns about inability to care for their children, adverse effects from medications taken during pregnancy, and genetic transmission of their disease to offspring lead to fewer pregnancies in women with RA and SLE. "Further study of the underlying causes of infertility and pregnancy loss in women with RA and SLE is needed to help fulfill their desire for children," concludes Dr. Clowse.


'/>"/>
Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. Circulatory Disorder Not Studied Enough in Women, Experts Say
2. Female cancer survivors have worse health behaviors than women with no cancer history
3. Risk of Preterm Birth Rises for Hispanic Women the Longer Theyre in U.S.
4. Study finds pregnant women with prior cesarean choose the delivery method preferred by their doctor
5. Women born to older mothers have a higher risk of developing breast cancer
6. Diabetes Takes Toll on Womens Hearing: Study
7. Triglyceride levels predict stroke risk in postmenopausal women
8. The NIH urges women to protect their heart health
9. Heartburn Drugs May Raise Fracture Risk in Older Women
10. Risks of pregnancy via egg donation similar for women over age 50 as for younger women
11. Women not following through with recommended breast screening MRI
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/31/2016)... London, Ontario (PRWEB) , ... May 31, 2016 , ... ... more than 2,000 clients already know – London is home to Ontario’s leading day ... and direction of visionary Fayez Tamba began with a unique concept to combine spa ...
(Date:5/31/2016)... ... , ... In his latest video, renowned AstroNumerologist Jesse Kalsi ... presidential candidate Donald Trump as an example, Kalsi describes the way AstroNumerology conveys ... adding numbers up,” says Kalsi. “It is about looking at each individual number, ...
(Date:5/31/2016)... , ... May 31, 2016 , ... Interest is on ... screening tool and as an orthogonal tool for RNAi hit validation. A key reason ... specific guide RNAs—allows rapid generation of CRISPR RNA (crRNA) collections in arrayed formats. ...
(Date:5/31/2016)... ... ... In a recent interview on The Greenburgh Report radio show hosted by Greenburgh, NY ... AM), leading medical insurance advocate Adria Goldman Gross discussed several eye-opening issues that have ... During the interview with Mr. Feiner that aired on May 7, 2016, Ms. Gross, ...
(Date:5/31/2016)... Chicago, IL (PRWEB) , ... May 31, 2016 ... ... industry-leading multichannel marketing services firm and statement solutions provider, for the ... released in the May 2016 issue of Advertising Age, and SourceLink ranked eighteenth ...
Breaking Medicine News(10 mins):
(Date:5/31/2016)...   Plexus Technology Group, LLC (Plexus ... systems (AIMS), is pleased to announce the addition ... of Technology. In this new capacity, Mr. Marcey ... company,s technological development. He will collaborate with each ... expansion of new products, product features and enhancements.  ...
(Date:5/31/2016)... York , May 31, 2016 ... essential ingredient in food, cosmetics and pharmaceuticals, with global ... revenues worth US$ 1.6 Bn. Demand for ... products, juices, and yogurts will continue its upward momentum ... trend will also boost positive sentiment on aloe vera, ...
(Date:5/31/2016)... Israel , May 31, 2016 ... its proprietary plant-based rhCollagen technology for tissue repair products ... Chief Scientist of Israel,s Ministry ... 12 million development project for 2016. The Chief Scientist,s grant ... year,s authorized grant, which totaled NIS 4.7 million.  ...
Breaking Medicine Technology: