Navigation Links
Women with polycystic ovary syndrome have higher BPA blood levels
Date:6/21/2010

Women with the polycystic ovary syndrome (PCOS), the most common hormone imbalance in women of reproductive age, may be more vulnerable to exposure to the chemical bisphenol A (BPA), found in many plastic household items, according to a new study. The results will be presented Sunday at The Endocrine Society's 92nd Annual Meeting in San Diego.

The study found that BPA, a known hormone disrupter, is elevated and associated with higher levels of male hormones in the blood of women with PCOS compared with healthy women. These findings held true for both lean and obese women with PCOS, said Evanthia Diamanti-Kandarakis, MD, PhD, study co-author and professor at the University of Athens Medical School in Greece.

"Women with the polycystic ovary syndrome should be alert regarding this environmental contaminant's potential adverse effects on reproductive aspects of their health problem," she said.

Excessive secretion of androgensmasculinization-promoting hormonesoccurs in PCOS. The syndrome raises the risk of infertility, obesity, Type 2 diabetes and heart disease.

Past studies show that BPA is elevated in women who have had recurrent miscarriages. This chemical can leach into the bloodstream from food and beverage containers that are made of polycarbonate hard plastic or lined with epoxy resins, or from some dental sealants and composites.

In the new study, the researchers divided 71 women with PCOS and 100 healthy female control subjects into subgroups matched by age and body composition (obese or lean). Blood levels of BPA, compared with those of controls, were nearly 60 percent higher in lean women with PCOS and more than 30 percent higher in obese women with the syndrome.

Additionally, as the BPA blood level increased, so did the concentrations of the male sex hormone testosterone and androstenedione, a steroid hormone that converts to testosterone, Diamanti-Kandarakis reported.

Although BPA is a weak estrogen, excessive secretion of androgens, as seen in PCOS, interfere with BPA detoxification by the liver, leading to accumulation of blood levels of BPA, Diamanti-Kandarakis explained.

"BPA also affects androgen metabolism, creating a vicious circle between androgens and BPA," she said.

Diamanti-Kandarakis said women with PCOS may want to limit their exposure to BPA.

"However," she said, "no one has proved that by reducing BPA levels in PCOS, it will have beneficial effects."


'/>"/>

Contact: Aaron Lohr
alohr@endo-society.org
240-482-1380
The Endocrine Society
Source:Eurekalert

Related medicine news :

1. Women Arent Waiting to Seek Infertility Help
2. Fertility Fact vs. Fiction: Women Recognizing Age as a Major Obstacle
3. Women Riders to Rev for a Cure at Daytona Bike Week
4. Global Aids Alliance Celebrates the Introduction of the International Violence Against Women Act, Urges Swift Passage
5. Chinese-American and Korean-American women at highest risk for diabetes in pregnancy
6. New Research Shows Genes of Pregnant Women and Their Fetuses Can Increase the Risk of Preterm Labor
7. Genes of pregnant women and their fetuses can increase the risk of preterm labor
8. Go Red For Women(R) and Jennie Garth Ask Women to Speak Up About Their No. 1 Killer
9. Life Line Screening Supports the American Heart Association's 'Go Red for Women' Event in Denver, Colorado
10. Women should be allowed to eat, drink during labor: Queens University researcher
11. Major New Study Finds Soyfoods Safe and Beneficial for Women With Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... Pixel Film Studios Released ProSlice Levels, a Media ... give their videos a whole new perspective by using the title layers in ... Studios. , ProSlice Levels contains over 30 Different presets to choose from. ...
(Date:6/26/2016)... Clarkston, Michigan (PRWEB) , ... June 26, 2016 ... ... respect to fertility once they have been diagnosed with endometriosis. These women need ... but they also require a comprehensive approach that can help for preservation of ...
(Date:6/25/2016)... ... ... closing of Bruton Memorial Library on June 21 due to a possible lice infestation, as ... of head lice: the parasite’s ability to live away from a human host, and to ... one in the event that lice have simply gotten out of control. , As lice ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern ... Laude and his M.D from the David Geffen School of Medicine at UCLA. He ... Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the ... In terms of the latter, setting the bar too high can result in disappointment, ... just slow progress toward their goal. , Research from PsychTests.com reveals ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... LEXINGTON, Mass. , June 24, 2016   ... specialty pharmaceutical company developing innovative inhaled drugs, announced today ... when Russell Investments reconstituted its comprehensive set ... 2016. "This is an important milestone for ... "It will increase shareholder awareness of our progress in ...
(Date:6/23/2016)... Research and Markets has announced the ... to 2022" report to their offering. ... patients with kidney failure, it replaces the function of kidneys ... blood and thus the treatment helps to keep the patient ... Increasing number of ESRD patients & substantial ...
(Date:6/23/2016)... Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that it ... (procalcitonin) assay as a dedicated testing solution for people ... Roche is the first IVD company in the U.S ... assessment and management. PCT is a sepsis-specific ... blood can aid clinicians in assessing the risk of ...
Breaking Medicine Technology: