Navigation Links
Women with polycystic ovary syndrome have higher BPA blood levels
Date:6/21/2010

Women with the polycystic ovary syndrome (PCOS), the most common hormone imbalance in women of reproductive age, may be more vulnerable to exposure to the chemical bisphenol A (BPA), found in many plastic household items, according to a new study. The results will be presented Sunday at The Endocrine Society's 92nd Annual Meeting in San Diego.

The study found that BPA, a known hormone disrupter, is elevated and associated with higher levels of male hormones in the blood of women with PCOS compared with healthy women. These findings held true for both lean and obese women with PCOS, said Evanthia Diamanti-Kandarakis, MD, PhD, study co-author and professor at the University of Athens Medical School in Greece.

"Women with the polycystic ovary syndrome should be alert regarding this environmental contaminant's potential adverse effects on reproductive aspects of their health problem," she said.

Excessive secretion of androgensmasculinization-promoting hormonesoccurs in PCOS. The syndrome raises the risk of infertility, obesity, Type 2 diabetes and heart disease.

Past studies show that BPA is elevated in women who have had recurrent miscarriages. This chemical can leach into the bloodstream from food and beverage containers that are made of polycarbonate hard plastic or lined with epoxy resins, or from some dental sealants and composites.

In the new study, the researchers divided 71 women with PCOS and 100 healthy female control subjects into subgroups matched by age and body composition (obese or lean). Blood levels of BPA, compared with those of controls, were nearly 60 percent higher in lean women with PCOS and more than 30 percent higher in obese women with the syndrome.

Additionally, as the BPA blood level increased, so did the concentrations of the male sex hormone testosterone and androstenedione, a steroid hormone that converts to testosterone, Diamanti-Kandarakis reported.

Although BPA is a weak estrogen, excessive secretion of androgens, as seen in PCOS, interfere with BPA detoxification by the liver, leading to accumulation of blood levels of BPA, Diamanti-Kandarakis explained.

"BPA also affects androgen metabolism, creating a vicious circle between androgens and BPA," she said.

Diamanti-Kandarakis said women with PCOS may want to limit their exposure to BPA.

"However," she said, "no one has proved that by reducing BPA levels in PCOS, it will have beneficial effects."


'/>"/>

Contact: Aaron Lohr
alohr@endo-society.org
240-482-1380
The Endocrine Society
Source:Eurekalert

Related medicine news :

1. Women Arent Waiting to Seek Infertility Help
2. Fertility Fact vs. Fiction: Women Recognizing Age as a Major Obstacle
3. Women Riders to Rev for a Cure at Daytona Bike Week
4. Global Aids Alliance Celebrates the Introduction of the International Violence Against Women Act, Urges Swift Passage
5. Chinese-American and Korean-American women at highest risk for diabetes in pregnancy
6. New Research Shows Genes of Pregnant Women and Their Fetuses Can Increase the Risk of Preterm Labor
7. Genes of pregnant women and their fetuses can increase the risk of preterm labor
8. Go Red For Women(R) and Jennie Garth Ask Women to Speak Up About Their No. 1 Killer
9. Life Line Screening Supports the American Heart Association's 'Go Red for Women' Event in Denver, Colorado
10. Women should be allowed to eat, drink during labor: Queens University researcher
11. Major New Study Finds Soyfoods Safe and Beneficial for Women With Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... (PRWEB) , ... June 27, 2016 , ... "FCPX editors ... customizable inside of Final Cut Pro X," said Christina Austin - CEO of Pixel ... style. Final Cut Pro X users can now reveal the media of ...
(Date:6/27/2016)... ... June 27, 2016 , ... ... industry today announced its strategic partnership with Connance, a healthcare industry leader ... two companies’ proven, proprietary technology combine to provide health systems, hospitals and ...
(Date:6/27/2016)... ... June 27, 2016 , ... TopConsumerReviews.com recently awarded their ... Eyeglasses . , Millions of individuals in the United States and Canada wear eyeglasses. ... way to both correct vision and make a fashion statement. Even celebrities use glasses ...
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a ... and World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is ... to some of the world’s leading providers of cereal and other breakfast foods. Its ...
(Date:6/26/2016)... , ... June 26, 2016 , ... PawPaws brand ... new product that was developed to enhance the health of felines. The formula is ... The two main herbs in the PawPaws Cat Kidney Support Supplement Soft ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- Revolutionary technology includes multi-speaker listening to ... leaders in advanced audiology and hearing aid technology, has ... the world,s first internet connected hearing aid that opens ...      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ) , ... firsts,: , TwinLink™ - the first dual ...
(Date:6/23/2016)... , June 23, 2016 The vast majority ... outpatient dialysis facility.  Treatments are usually 3 times a ... per visit, including travel time, equipment preparation and wait ... but especially grueling for patients who are elderly and ... skilled nursing and rehabilitation centers for some duration of ...
(Date:6/23/2016)... , June 23, 2016  Experian ... integrating and transforming the patient payment and ... several innovative new products and services that ... its revenue cycle offerings. These award-winning solutions ... efficient workflows, remain compliant in an ever-changing ...
Breaking Medicine Technology: