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Women with atrial fibrillation are at significantly higher risk of stroke and death compared to men
Date:9/22/2009

th atrial fibrillation and developed the following management recommendations:

  • Women have a higher incidence of stroke and mortality than do men.
    Emphasize therapies to prevent atrial fibrillation and ensure safe management once diagnosed.

  • Women are not prescribed blood thinners (anticoagulation therapy) as often as are men, which results in a higher incidence of formation of blood clots that break loose and block other vessels.
    Assess the risk/benefit ratio individually for each woman with atrial fibrillation.

  • Women have a greater risk of bleeding from anticoagulation therapy than do men.
    Monitor anticoagulation therapy carefully to avoid bleeding.

  • Women have a higher risk of life-threatening arrhythmias and slow heart rates requiring permanent pacing when treated with antiarrhythmic drugs.
    Monitor female patients taking antiarrhythmia drugs carefully.

  • Women have hormonal fluctuations.
    Be aware that hormonal fluctuations during the normal menstrual cycle can cause more life-threatening arrhythmias.

  • Women have a higher risk of low potassium levels in the blood, increasing the risk of drug-related arrhythmias.
    Monitor serum and potassium levels carefully.

  • Women have a higher sensitivity to supportive therapies such as statins and vasodilators.
    Pay close attention to hepatic and renal function.

  • Women are referred less often or later for non-drug management such as pacemaker implantation or ablation.
    Remember that ablative therapy is an option for symptomatic women because of similar success rates in men.

  • Women with atrial fibrillation have a lower quality of life.
    Careful assessment of symptoms, symptom relief, and adequate rate control or rhythm control can improve quality of life.

"For women with atrial fibrillation, these gender differences should always be kept in mind to help prevent strokes and heart
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Contact: Deb Song
deb_song@rush.edu
312-942-0588
Rush University Medical Center
Source:Eurekalert

Page: 1 2 3

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