Navigation Links
Women undergoing PCI display greater number of co-morbidities than men
Date:10/31/2011

New research shows that women undergoing percutaneous coronary intervention (PCI), also known as angioplasty, exhibit more co-morbidities and cardiovascular risk factors than men. Risk-adjusted analyses have now indicated that, in the contemporary era, gender is not an independent mortality predictor following PCI according to the study now available in Catheterization and Cardiovascular Interventions, a journal published by Wiley-Blackwell on behalf of The Society for Cardiovascular Angiography and Interventions (SCAI).

Each year more than one million Americans undergo PCI to open blocked arteries according to the National Heart, Lung and Blood Institute. Prior studies have given conflicting reports regarding the outcomes of females versus males after PCI, with some suggesting women have poorer outcomes compared to men and others finding little or no difference. This contradiction in results has remained under dispute, with some experts suggesting that improved PCI techniques, modification of risk-factors and pharmacological advances may balance adverse outcomes between the genders.

To clarify these gender differences, Annapoorna Kini, MD, and colleagues from Mount Sinai Hospital in New York, explored PCI outcomes in a racially diverse patient group at a high-volume, tertiary hospital. The team identified 4761 female and 8991 male patients at their institution who underwent PCI between April 2003 and 2009. Information including clinical characteristics, procedural details, laboratory and diagnostic test results, as well as 30-day and 1-year follow-up data, was collected.

"Our findings extend previous research, and definitively show that following PCI, women do not have an inherently greater mortality risk compared to men," explains Dr. Kini. "However, we did find that prognostic risk factors were significantly more prevalent in women." Results showed that compared to men, females were older, and were more likely to have hypertension, diabetes, and higher LDL cholesterol levels. Kini added, "While men did have higher rates of some modifiable risk-factors, such as smoking, women certainly had a far greater overall burden of co-morbidities and adverse prognostic factors." The data showed that a greater number of women also presented with an unstable coronary syndrome.

In the key findings of this study, the unadjusted post-PCI mortality rate was higher in women compared with men, with 30-day rates of 1.3% versus 0.8%; one-year at 6.1% versus 4.8%; and three-year at 10.4% versus 8.4%. Adjusted modeling, however, which accounted for the gender-imbalance in risk factors, proved that women were not at higher mortality risk than men following PCI in this racially diverse group. Dr. Kini concluded, "While our study found no risk-adjusted difference in mortality between men and women, both sexes would benefit from attention to modifying factors that reduce the risk of heart diseaseeliminating smoking, engaging in physical activity, and eating a healthy diet."

The Centers for Disease Control and Prevention (CDC) reports that heart disease is the leading cause of death among men and women, killing more than one in every four Americans.


'/>"/>
Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. Company Invites Women to STOP PMS - Take the 10-Minute Challenge
2. LifestyleMom.com and the LifestyleMom Radio Cafe Aim to Help Women Create a Family Life and "Me Life" That They Truly Love
3. Women More Likely to Fail Treatment for Atrial Fibrillation
4. Diabetes drug ups risk for bone fractures in older women
5. Womens Heart Disease Awareness Still Lacking
6. Cyndi Lauper, Lady Gaga Put Spotlight on Women and HIV
7. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
8. Womens Dermatologic Society Marks 35th Anniversary with Release of Unprecedented Book of Wisdom and Inspiration
9. Few Women at High Risk for Breast Cancer Take Tamoxifen
10. Diane von Furstenberg Establishes The DVF Awards to Recognize Outstanding Women Leaders
11. YazTalk Warns Women of Life Threatening Side Effects
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2017)... ... 24, 2017 , ... The weather is heating up and the days are ... should be aware that the summer months provide more than warmer temperatures that are ... can be negatively affected from direct exposure to the sun. When it comes to ...
(Date:6/23/2017)... , ... June 23, 2017 , ... By scoring 100% ... ninth consecutive four-star rating from premier online charity evaluator, Charity Navigator, validating ANRF's work ... 1% of all charities reviewed by Charity Navigator and earns ANRF a spot on ...
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... ... plastic surgeon practicing in Newburgh, New York, has recently begun offering three new ... to offering the best cutting-edge procedures and reducing downtime, Dr. Rubinstein is excited ...
(Date:6/23/2017)... Hills, CA (PRWEB) , ... June 23, 2017 , ... ... plane facelift . Dr. Talei has come up with a proprietary technique that ... releases and lifts tissues that have dropped. For all ages, patients can expect to ...
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... MD ... Florida. This is MD Now’s 28th facility overall and marks the urgent care center's ... located one mile North of The Falls shopping mall. The new clinic offers a ...
Breaking Medicine News(10 mins):
(Date:6/20/2017)...  Hill-Rom Holdings, Inc. (NYSE: HRC), will host its fiscal ... July 28, 2017, beginning at 7:30 a.m. (CDT) / 8:30 ... To participate in the conference call, dial (877) 304-8969 (domestic) ... least 10 minutes prior to the start to allow time ... Webcast: A simultaneous webcast of the ...
(Date:6/16/2017)... , June 16, 2017  Exactly 50 years ago ... off what later became known as the San Francisco "Summer ... ) is unveiling two radical innovations in strategic market research ... This announcement marks the beginning of Northern Light,s "Summer of ... ...
(Date:6/14/2017)... -- In 2016, Embodied Labs took top prize ... came away with $25,000 in seed-fund investment. Embodied Labs ... "entering the life of another" and by the Journal ... medical professionals in an entirely new dimension." Building upon ... for the Department of Education,s EdSimChallenge, where they received ...
Breaking Medicine Technology: