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Women less likely to die after TAVI than men
Date:9/2/2013

variables on one year mortality. Figure 1 shows women's survival advantage at 12 months. Even after adjustment, female gender was an independent predictor for one-year survival after TAVI with a hazard ratio of 0.75. Dr Sherif said: "This means that women are 25% less likely to die after TAVI than men.

Dr Sherif said: "Lower levels of fibrosis in women might explain the more rapid reversal of myocardial hypertrophy after correction of aortic stenosis and might partially explain the better outcome in women compared with men.3 This might account for the time delay in the female advantage, since the reversal process takes longer than 30 days."

He added: "As a limitation for registry data, these data are observational, and therefore can only be considered to be hypothesis generating rather than causative."

Dr Sherif concluded: "Future work should focus on the effect of sex differences in outcomes for intermediate risk patients undergoing TAVI, and provide longer-term follow up for high-risk patients."


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Contact: Celine Colas
press@escardio.org
44-773-005-7146
European Society of Cardiology
Source:Eurekalert

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