Navigation Links
Women fare better than men with metastatic colorectal cancer -- are hormones helping?
Date:9/29/2009

PHILADELPHIA Younger women with metastatic colorectal cancer lived longer than younger men. However, this survival advantage disappeared with age, suggesting a benefit from estrogen or other hormones, according to results of a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

"We've known for a while that estrogen prevents colorectal cancer, but this is the first study to suggest it may improve outcomes once you have colorectal cancer," said Heinz-Josef Lenz, M.D., co-director of gastrointestinal oncology and colorectal cancer at the University of Southern California/Norris Comprehensive Cancer Center, Keck School of Medicine.

Using the Surveillance, Epidemiology and End Results registry, Lenz and colleagues screened 52,882 patients who had metastatic colorectal cancer between 1988 and 2004.

Women age 18 to 44 years had significantly longer survival than men at 17 months compared with 14 months. However, older women had significantly shorter overall survival at seven months compared with nine months.

Lenz said these results suggest that estrogen levels may be playing a significant role in prognosis. James Abbruzzese, M.D., chair of gastrointestinal medical oncology at the University of Texas M. D. Anderson Cancer Center and a deputy editor of Clinical Cancer Research, agreed that hormones may certainly play a role, but says a look at the data broken down by year is also intriguing. Specifically, those diagnosed after 2000 have improved survival; those diagnosed before 2000 had a less pronounced survival advantage.

"In terms of the chemotherapy we have available, since 2000 the regimens employ more agents and have become much more aggressive. Therefore, it may be expected to inhibit normal hormonal cycles leading to lower hormonal levels in these women, so other factors may be playing a role as well. It may not just be hormones," said Abbru
'/>"/>

Contact: Jeremy Moore
jeremy.moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Boston University School of Medicines black womens health study receives $9.1 million award
2. Women who make poor shoe choices at risk for foot pain later in life
3. Autoimmune Disorder Linked to Stroke, Heart Attack in Women
4. More Women Having Other Breast Removed
5. Irregular Heartbeat Risk Higher in Women With Type 2 Diabetes
6. Scientists Discover How Chemo Can Make Women Infertile
7. More women choosing to remove healthy breast after cancer diagnosis
8. Women With Atrial Fibrillation Face Rougher Road Than Men
9. Free Upcoming Program Scheduled to Help Remove Barriers To Early Cervical and Breast Cancer Diagnosis for Local Women
10. A Staggering 7 Out of 10 Women Facing Breast Cancer Are Never Told of Their Options
11. Women living in group homes need to learn to make decisions about leisure time to enrich their lives
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Women fare better than men with metastatic colorectal cancer -- are hormones helping?
(Date:4/21/2015)... “ ZeroWire ” was featured on NewsWatch as ... look at the latest and coolest technology products and ... for NewsWatch and a technology expert, conducted the review ... system and lifestyle management hub. , According to the ... burglaries in 2010. It goes without saying that home ...
(Date:4/21/2015)... Dallas, Texas (PRWEB) April 21, 2015 ... Review, H1 2015” provides comparative analysis on ... strengthens R&D pipelines by identifying new targets ... products. Complete report with TOC is available ... report also reviews key players involved in ...
(Date:4/21/2015)... NJ (PRWEB) April 21, 2015 ... across platforms and devices, today announced a new enhancement ... of the new Microsoft Office 365 Management Activity API. ... customers to fully audit and take action on all ... , “The new Office 365 Management Activity API provides ...
(Date:4/21/2015)... York, NY (PRWEB) April 21, 2015 ... of advanced delivery technologies and development solutions for ... the launch of ADVASEPT™ Lock, a stopper-less, glass- ... delivery of injectable medications. Easily opened, ADVASEPT Lock ... convenient and functional container closure with the security ...
(Date:4/21/2015)... 2015 The report “Dermatitis ... analysis on the therapeutic development for Dermatitis. ... identifying new targets and MOAs to produce ... TOC is available @ http://www.rnrmarketresearch.com/dermatitis-pipeline-review-h1-2015-market-report.html ... players involved in the therapeutic development for ...
Breaking Medicine News(10 mins):Health News:A Leader in Home Security was Featured on NewsWatch Television 2Health News:Sinusitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 2Health News:Sinusitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 3Health News:AvePoint Integrates Microsoft Office 365 Management Activity API into DocAve Policy Enforcer for Proactive SharePoint Monitoring 2Health News:AvePoint Integrates Microsoft Office 365 Management Activity API into DocAve Policy Enforcer for Proactive SharePoint Monitoring 3Health News:Catalent Announces the Expansion of its Advanced, Aseptic, Glass-Free Injectable Platform with New ADVASEPT™ Lock Delivery Technology 2Health News:Dermatitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 2Health News:Dermatitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 3Health News:Dermatitis Therapeutic Development and Pipeline Market Review H1 2015 Available at RnRMarketResearch.com 4
... Smoking has been linked to a number of ... disorders, among others. Early smoking is shown to ... disorders (e.g., panic disorder, generalized anxiety disorder), and ... anxiety) increases the risk for later development of ...
... now become common place owing to the wide scale ... over again, scientists have been working on ways to ... results of a recent research have recently confirmed that ... diseases. ,The leeches have added to the ...
... A new study says that botulinum toxin can be useful ... trigeminal neuralgia. Botulinum or botox as it is popularly known ... and eye spasms. ,Researchers in Brazil and the United ... have detailed their findings in a study published in the ...
... Kollywood stars like Kamal Hassan, Chiranjeevi, Nagarjuna, Venkatesh, Vikram, ... to spread the awareness on AIDS. ,The show ... the Melinda and Bill Gates Foundation was an evening of ... anything in partnership with others. I am very proud of ...
... is likely to invoke the compulsory licensing (CL) provision ... //firms to produce and stockpile Swiss drug maker Roche’s ... against the most dreaded avian flu virus. , ... receipt of an application from the industry. Furthermore, the ...
... Abdominal wall hernias are one of the most common ... repairs// performed annually. Although ventral hernia repair (VHR) is ... problem. Wound infection has been identified as a consistent ... recent study, which appears in the November issue of ...
Cached Medicine News:Health News:Smokers Are Prone To Number Of Psychiatric Disorders 2Health News:Leeches Provide Clues Regarding The Prevention Of Heart Disease 2Health News:Predictors Of Wound Infection In Ventral Hernia Repair 2
(Date:4/21/2015)... April 21, 2015   Rock Creek Pharmaceuticals, Inc., ... focused on the treatment of chronic inflammatory disorders, announced ... to the Company,s Board of Directors with the recent ... a new director. Michael Mullan ... Pharmaceuticals, said, "Dr. Samuel,s experience in advancing biotechnology products ...
(Date:4/21/2015)... , April 21, 2015  Direct contracting continues ... as aptitude marks its second anniversary.  With over ... platform, single hospital entities, large integrated delivery systems ... that cover medical surgical items, clinical preference products ... cost effective - complementary contracting strategy, aptitude seeks ...
(Date:4/21/2015)... , April 21, 2015  Game-changing ... the latest being the European Commission,s ruling on ... global leader and champion of pharmaceutical supply ... of meeting these mandates and offers several tools ... many countries. From an upcoming webinar in May ...
Breaking Medicine Technology:Rock Creek Pharmaceuticals Appoints New Director and Provides Notice of Settlement of Derivative Litigation 2Rock Creek Pharmaceuticals Appoints New Director and Provides Notice of Settlement of Derivative Litigation 3Rock Creek Pharmaceuticals Appoints New Director and Provides Notice of Settlement of Derivative Litigation 4Rock Creek Pharmaceuticals Appoints New Director and Provides Notice of Settlement of Derivative Litigation 5Rock Creek Pharmaceuticals Appoints New Director and Provides Notice of Settlement of Derivative Litigation 6Rock Creek Pharmaceuticals Appoints New Director and Provides Notice of Settlement of Derivative Litigation 7Healthcare's first direct contracting market celebrates second anniversary 2Frequentz Gives the Global Pharmaceutical Supply Chain a Shoulder to Lean On as They Face Expanding Serialization Requirements 2Frequentz Gives the Global Pharmaceutical Supply Chain a Shoulder to Lean On as They Face Expanding Serialization Requirements 3
Inquire...
The autoclavable, aluminum needle box is designed to store loaded needles and help protect personnel from exposure. Each shield consists of an aluminum box with faceplate to match the grid pattern th...
... Brachytherapy loaders allow for efficient, easy ... Connectors to your customized plans at ... Bard loaders is the flexibility to ... in the QuickLoad™ Loader allows for ...
... designed to help you achieve one important ... procedure. All needles are engineered for exceptional ... for smooth entry and exit. A broad ... an ideal match with procedural needs and ...
Medicine Products: