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Women fare better than men, but need more blood after kidney cancer surgery
Date:5/15/2012

DETROIT Women do better than men after surgical removal of part or all of a cancerous kidney, with fewer post-operative complications, including dying in the hospital, although they are more likely to receive blood transfusions related to their surgery.

But Henry Ford Hospital researchers who documented these gender differences can't say why they exist.

The results of the new study, based on population samples from throughout the U.S., will be presented this week at the American Urological Association's Annual Meeting in Atlanta.

"This is a controversial area," says Quoc-Dien Trinh, M.D., a Fellow at Henry Ford Hospital's Vattikuti Urology Institute and lead author of the study.

"While the effects of gender on the outcome of many types of surgery, including removal of the bladder, have been demonstrated and widely debated, the association between gender and surgical outcomes of nephrectomy (kidney removal) is not well understood."

Physical differences between genders can explain different outcomes in some types of surgery, and have been shown and discussed in several earlier studies, Dr. Trinh says. "But this is hard to explain for nephrectomies. There is no clear-cut anatomical difference between men and women that would explain why it's easier or harder in one sex than the other."

Surgical removal of part or all of a diseased kidney, whether using traditional "open" techniques or less-intrusive laparoscopic procedures, is the standard of care for kidney cancer and the only curative treatment.

Using nephrectomy data from 1998 through 2007, the most recent available from the Health Care Utilization Project's Nationwide Inpatient Sample (NIS), "we tested the rates of blood transfusions, extended length of stay (beyond the median of five days), in-hospital mortality, as well as complications during and after surgery, separated by gender," Dr. Trinh says.

Of the total 48,172 cases that we
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Contact: Krista Hopson
khopson1@hfhs.org
313-874-7207
Henry Ford Health System
Source:Eurekalert

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