Navigation Links
Women fare better than men, but need more blood after kidney cancer surgery
Date:5/15/2012

DETROIT Women do better than men after surgical removal of part or all of a cancerous kidney, with fewer post-operative complications, including dying in the hospital, although they are more likely to receive blood transfusions related to their surgery.

But Henry Ford Hospital researchers who documented these gender differences can't say why they exist.

The results of the new study, based on population samples from throughout the U.S., will be presented this week at the American Urological Association's Annual Meeting in Atlanta.

"This is a controversial area," says Quoc-Dien Trinh, M.D., a Fellow at Henry Ford Hospital's Vattikuti Urology Institute and lead author of the study.

"While the effects of gender on the outcome of many types of surgery, including removal of the bladder, have been demonstrated and widely debated, the association between gender and surgical outcomes of nephrectomy (kidney removal) is not well understood."

Physical differences between genders can explain different outcomes in some types of surgery, and have been shown and discussed in several earlier studies, Dr. Trinh says. "But this is hard to explain for nephrectomies. There is no clear-cut anatomical difference between men and women that would explain why it's easier or harder in one sex than the other."

Surgical removal of part or all of a diseased kidney, whether using traditional "open" techniques or less-intrusive laparoscopic procedures, is the standard of care for kidney cancer and the only curative treatment.

Using nephrectomy data from 1998 through 2007, the most recent available from the Health Care Utilization Project's Nationwide Inpatient Sample (NIS), "we tested the rates of blood transfusions, extended length of stay (beyond the median of five days), in-hospital mortality, as well as complications during and after surgery, separated by gender," Dr. Trinh says.

Of the total 48,172 cases that were identified and examined, 18,966 (39.4 percent) were female. The mean age for the women was 62.7 years; for the men, 61.8 years.

While no significant gender-related differences were found in complications during surgery and length of hospital stay after surgery, the Henry Ford Hospital researchers found that women:

  • Were less likely than men (14.6 percent vs. 17.1 percent) to have complications after nephrectomy. These included digestive problems, hemorrhage, cardiac complications and infections.
  • Were less likely to die while in the hospital (0.6 percent vs. 0.8).
  • Were more likely to have blood transfusions than men (11.5 percent vs.9.2 percent).

The differences were most pronounced after partial removal of a cancerous kidney using open surgical techniques.

Because researchers didn't have specific data on the kidney tumors in each individual case, exactly why these differences were found couldn't be determined, Dr. Trinh says, adding, "It is entirely possible that women have smaller tumors, so there are fewer complications."

As to the higher rates of blood transfusion in female patients, Dr. Trinh says the reason or reasons remain unknown.

"The threshold for transfusion could be different between men and women," he says. "We usually transfuse based on clinical decisions: we look at the patients, how they're doing, and make judgments. There are no clear-cut guidelines.

"In the end, women are transfused more often. Is it because they bleed more often? Are they transfused more liberally than men? We don't have the data to answer this."

While these differences remain to be explored and determined, the fact that they exist, and have now been documented, is a step forward in the treatment of kidney cancer.

"Insight into the effect of gender on major urologic oncology procedures," Dr. Trinh says, "is critical in reducing disparities in care and improving patient outcomes."


'/>"/>

Contact: Krista Hopson
khopson1@hfhs.org
313-874-7207
Henry Ford Health System
Source:Eurekalert

Related medicine news :

1. Company Invites Women to STOP PMS - Take the 10-Minute Challenge
2. LifestyleMom.com and the LifestyleMom Radio Cafe Aim to Help Women Create a Family Life and "Me Life" That They Truly Love
3. Women More Likely to Fail Treatment for Atrial Fibrillation
4. Diabetes drug ups risk for bone fractures in older women
5. Womens Heart Disease Awareness Still Lacking
6. Cyndi Lauper, Lady Gaga Put Spotlight on Women and HIV
7. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
8. Womens Dermatologic Society Marks 35th Anniversary with Release of Unprecedented Book of Wisdom and Inspiration
9. Few Women at High Risk for Breast Cancer Take Tamoxifen
10. Diane von Furstenberg Establishes The DVF Awards to Recognize Outstanding Women Leaders
11. YazTalk Warns Women of Life Threatening Side Effects
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... The International Association of Eating ... excellence for the field of eating disorders, announces the opening of early registration ... Orlando, Florida at the Omni Resort at ChampionsGate. , The annual ...
(Date:10/13/2017)... ... October 13, 2017 , ... Southern ... and Jennifer Huggins, PharmD ’17, along with clinical associate professor Janice Frueh, ... cardiovascular diseases during the 15th Annual Women’s Health Conference. The SIU School ...
(Date:10/13/2017)... Shelton, CT (PRWEB) , ... October 13, 2017 , ... ... and long-term care services, staged a mock evacuation of the facility as part of ... Department, Shelton Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) of ... collection of specialty vendors and unique items from across the nation, this holiday-themed event ... wellness services offered by the VNA. The boutique will be open Saturday, November ...
(Date:10/13/2017)... NJ (PRWEB) , ... October 13, 2017 , ... Global ... at scenic Alexandria Park in Milford, NJ. This free event, sponsored by Global ... physical activity. The fun run is geared towards children of all ages; it ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... IRVING, Texas , Oct. 6, 2017   ... industry with more than $100 billion in purchasing power, ... industry news and information. The Newsroom is ... chain and industry trends, infographics, expert bios, news releases, ... Besides having access to a wealth of resources at ...
(Date:10/4/2017)... 4, 2017 OBP Medical , ... medical devices, today announced regulatory approval from ... (or Agência Nacional de Vigilância Sanitária (ANVISA)) to ... surgical retractor with integrated LED light source and ... and exposure of a tissue pocket or cavity ...
(Date:10/2/2017)... Halo Labs announces the European launch of their new low volume, ... 2017 in Cambridge, U.K on October 4th. ... samples with unprecedented speed and sensitivity while using far less sample ... ... system ...
Breaking Medicine Technology: