Navigation Links
Women With IBS Unable to Switch Off Pain Response
Date:1/9/2008

Finding could improve understanding of irritable bowel syndrome and lead to new treatments

WEDNESDAY, Jan. 9 (HealthDay News) -- Women with irritable bowel syndrome anticipate and react to pain differently than women without IBS, a new study suggests.

The University of California, Los Angeles researchers found that women with IBS can't effectively switch off a pain modulation mechanism in the brain, which makes them more sensitive to abdominal pain. The finding may help improve understanding of IBS and lead to new treatments for the disorder, which affects about 10 percent to 15 percent of the U.S. population, the researchers said.

There is no cure for IBS, which causes abdominal discomfort, along with diarrhea and/or constipation. Current treatments for IBS only lessen symptoms.

The study, published in the Jan. 9 issue of the journal Neuroscience, included 14 women with IBS and 12 women without the disorder. Researchers used functional magnetic resonance imaging (fMRI) to record the women's brain activity while they anticipated and experienced mild abdominal pain.

During anticipation of pain, women without IBS decreased activity in brain areas involved with pain and emotional arousal. But the women with IBS weren't able to reduce activity in these areas.

"The abdominal hypersensitivity that is a hallmark of IBS may represent an inability to downregulate pain and emotional arousal circuits," lead author Steven Berman, a senior research scientist at UCLA, said in a prepared statement. "IBS patients may have an inability to inhibit the competing tendency to upregulate emotional arousal in order to escape pain faster."

Both groups of women showed increased activity in pain arousal areas when they were subject to pain, but those with IBS showed greater increases in several brain areas.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about IBS.



-- Robert Preidt



SOURCE: University of California, Los Angeles, news release, Jan. 8, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Speaking of Womens Health Community Event Returns to All Wal-Mart Supercenters Nationwide January 12th
2. American women are more likely to choose overly aggressive treatments for breast cancer
3. Not All Women Need Digital Mammograms
4. Slim-Fast Celebrates Weight Loss by Hosting Style Your Slim(SM) Fashion Show Featuring Real Women
5. Religion habit cuts anxiety in women
6. Men need more Botox than women
7. Pesticides May Cause Asthma Among Farm Women
8. Handling pesticides associated with greater asthma risk in farm women
9. AHF Says Op-Out Clause is Crucial to New Jersey Law Requiring HIV Testing of Pregnant Women
10. Bald Women Get Their Heads Together in Southern California
11. BRCA1 Mutation Prevalent Among Hispanic, Younger Black Women
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Women With IBS Unable to Switch Off Pain Response
(Date:8/16/2017)... Atlanta, GA (PRWEB) , ... August 16, 2017 , ... ... the new Inc. 5000. The company ranked #4429 on the newly released, 36th annual ... The list represents a unique look at the most successful companies within the American ...
(Date:8/16/2017)... ... 2017 , ... In 1987, McDaniel & Durrett, P.C., a ... this year, and they’re marking the milestone by undertaking a significant office makeover, ... , It stands to reason that, given the central importance of gynecology to ...
(Date:8/16/2017)... ... August 16, 2017 , ... QualDerm Partners , a ... today announced Cumberland Skin Surgery and Dermatology has joined the company ... in both Hermitage and Lebanon, Tennessee, provides comprehensive general dermatology and skin cancer ...
(Date:8/16/2017)... Island, NY (PRWEB) , ... August 16, 2017 , ... ... with IV starts and blood draws. By broadly deploying AccuVein devices, Maury Regional Medical ... takes much of the guesswork out of a needle stick and more importantly, helps ...
(Date:8/16/2017)... ... August 16, 2017 , ... Paul Vitenas, MD, ... Connolly 2017 Top Doctor. The annual list identifies the nation’s top physicians, in a ... has made it to the top of Castle Connolly’s coveted ranking. , Castle Connolly ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... Aug. 15, 2017 AccuGenomics, Inc., a diagnostic ... today announced that the company has provided an AccuKit ... North Carolina at Chapel Hill and to Qura Therapeutics ... characterize and quantify HIV reservoir and viral expression in ... The HIV Cure Center is a joint initiative between ...
(Date:8/14/2017)... and PETACH TIKVAH, Israel ... (NASDAQ: BCLI), a leading developer of adult stem cell ... second quarter ending June 30, 2017. ... of preparing for our pivotal Phase 3 trial to ... Lebovits , President and Chief Executive Officer of BrainStorm. ...
(Date:8/10/2017)... 10, 2017  Physical Rehabilitation Network (PRN), acquired the long-standing ... Lakewood, Colorado . The reputable clinic will continue to ... DPT with his staff of four clinicians. Lipkin received his ... brings over 10 years of experience with a strong background ... PT marks the 10th PRN clinic in and around the ...
Breaking Medicine Technology: