Navigation Links
Women With IBS Unable to Switch Off Pain Response
Date:1/9/2008

Finding could improve understanding of irritable bowel syndrome and lead to new treatments

WEDNESDAY, Jan. 9 (HealthDay News) -- Women with irritable bowel syndrome anticipate and react to pain differently than women without IBS, a new study suggests.

The University of California, Los Angeles researchers found that women with IBS can't effectively switch off a pain modulation mechanism in the brain, which makes them more sensitive to abdominal pain. The finding may help improve understanding of IBS and lead to new treatments for the disorder, which affects about 10 percent to 15 percent of the U.S. population, the researchers said.

There is no cure for IBS, which causes abdominal discomfort, along with diarrhea and/or constipation. Current treatments for IBS only lessen symptoms.

The study, published in the Jan. 9 issue of the journal Neuroscience, included 14 women with IBS and 12 women without the disorder. Researchers used functional magnetic resonance imaging (fMRI) to record the women's brain activity while they anticipated and experienced mild abdominal pain.

During anticipation of pain, women without IBS decreased activity in brain areas involved with pain and emotional arousal. But the women with IBS weren't able to reduce activity in these areas.

"The abdominal hypersensitivity that is a hallmark of IBS may represent an inability to downregulate pain and emotional arousal circuits," lead author Steven Berman, a senior research scientist at UCLA, said in a prepared statement. "IBS patients may have an inability to inhibit the competing tendency to upregulate emotional arousal in order to escape pain faster."

Both groups of women showed increased activity in pain arousal areas when they were subject to pain, but those with IBS showed greater increases in several brain areas.

More information

The U.S. National Institute of Diabetes and Digestive and Kidney Diseases has more about IBS.



-- Robert Preidt



SOURCE: University of California, Los Angeles, news release, Jan. 8, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Speaking of Womens Health Community Event Returns to All Wal-Mart Supercenters Nationwide January 12th
2. American women are more likely to choose overly aggressive treatments for breast cancer
3. Not All Women Need Digital Mammograms
4. Slim-Fast Celebrates Weight Loss by Hosting Style Your Slim(SM) Fashion Show Featuring Real Women
5. Religion habit cuts anxiety in women
6. Men need more Botox than women
7. Pesticides May Cause Asthma Among Farm Women
8. Handling pesticides associated with greater asthma risk in farm women
9. AHF Says Op-Out Clause is Crucial to New Jersey Law Requiring HIV Testing of Pregnant Women
10. Bald Women Get Their Heads Together in Southern California
11. BRCA1 Mutation Prevalent Among Hispanic, Younger Black Women
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Women With IBS Unable to Switch Off Pain Response
(Date:6/26/2017)... RU (PRWEB) , ... June 26, 2017 , ... ... released a whitepaper that pledges to solve many catastrophic issues within funding campaigns. ... 2017. , The typical notion of crowdfunding - the raising of funds through the ...
(Date:6/25/2017)... ... ... FCPX LUT Vintage Volume 2 for Final Cut Pro X allows users ... contains 60 different color-grade presets, giving editors multiple options for adding different color options. ... subjects, plus much more. FCPX LUT Vintage Volume 2 is designed for any skill-set ...
(Date:6/25/2017)... ... ... Republicans in the United States Senate on Thursday released their version of ... differs significantly from the American Health Care Act, which the House passed in May, ... will have to take up the Senate version as-is, if it passes. , The ...
(Date:6/25/2017)... ... , ... CareSet Labs released the Root NPI Graph today at the 2017 ... improved version of the Doctor Referral teaming dataset commonly available from Medicare. , Originally ... the the “Doctor Referral Dataset” as released by Medicare and “DocGraph” as released by ...
(Date:6/25/2017)... ... 2017 , ... June is Men’s Health Month and the focus is on prostate ... in the U.S. and the third most common cause of cancer related death today; lung ... seven will be diagnosed with prostate cancer during his lifetime. Those at highest risk ...
Breaking Medicine News(10 mins):
(Date:6/7/2017)... -- Novavax, Inc., (Nasdaq: NVAX ) today announced that ... its RSV F protein recombinant nanoparticle vaccine candidate (RSV F ... in the journal Vaccine (the data ... conferences). The Company previously announced top line results ... RSV F Vaccine with the goal of protecting infants from ...
(Date:6/5/2017)... , June 5, 2017 The ... brand of Diplomat Pharmacy, Inc. (NYSE: DPLO), has been awarded ... Cincinnati Enquirer . Results are based on an ... in organizational health and workplace improvement. The survey measures several ... ...
(Date:6/3/2017)... , June 3, 2017  Eli Lilly and ... that results from the Phase 3 MONARCH 2 ... & 6 inhibitor, in combination with fulvestrant, significantly ... fulvestrant alone in women with hormone-receptor-positive (HR+), human ... cancer who have relapsed or progressed after endocrine ...
Breaking Medicine Technology: