Navigation Links
With proper planning, selective rather than mass vaccination can provide immunity against flu
Date:1/3/2011

Jerusalem, January 3. 2011 With the current outbreak of the flu season in Israel, hospitals are reporting overcrowding, and doctors are advising people who have not yet been vaccinated against flu to get their shots.

Surprisingly, however, three physicists -- one from the Hebrew University of Jerusalem and two others from the University of Michigan have developed an unconventional, theoretical strategy for intensive but limited vaccination against infectious diseases (such as flu) that would replace the practice of mass inoculation over a prolonged period. The physicists developed their theory using a technique borrowed from quantum mechanics.

How does it work? The program is based on accelerating the natural extinction of the disease through selective vaccination.

Prof. Baruch Meerson of the Racah Institute of Physics at the Hebrew University explains the strategy:

"Consider an unfortunate situation when an infectious disease has spread over a population, and a certain portion of the population is sick. Most of the infected individuals recover from the disease and develop immunity to it. On the other hand, the infected individuals can spread the disease in the population through contacts with susceptible individuals.

"To reduce the infection spread, one can vaccinate all possible susceptible individuals. If they are all willing to be vaccinated and there is enough vaccine for everybody, the vaccination campaign will eradicate the disease with certainty. Very often, however, a large portion of susceptible individuals refuse to be vaccinated. In addition, a vaccine can be in short supply, expensive to produce, or difficult to store."

How to cope with such conditions is the problem tackled by the three physicists: Meerson from the Hebrew University and Prof. Mark Dykman and Dr. Michael Khasin from Michigan State University in the US. (Although presently working in the US, Dr. Khasin earned his doctorate at the Hebrew University.)

The researchers made use of the fact that, even without vaccination, a disease ultimately becomes extinct on its own. But for large populations, the typical time it takes for the disease to disappear by itself can be very long. Essentially, Meerson and colleagues suggested an optimal vaccination strategy that accelerates, in the maximum possible way, this natural process of disease disappearance.

In this strategy, the vaccine must be delivered to the most susceptible populations (say children in a particular class where a certain percentage of the pupils have come down with the flu) in the form of short but intensive vaccination periods, adjusted to match the "ups and downs" of waves that occur in the natural spread of infectious disease.

Also, when the disease has a seasonal variation (like the common cold), that factor must be taken into consideration in the vaccination timing calculations.

The question that still remains is why physicists took on a problem belonging to epidemiology? Meerson says that the mathematical model that he and his colleagues used in their analysis closely resembles a quantum-mechanical model that physicists use when analyzing the dynamics of microscopic particles (such as electrons) in miniature traps. By adjusting the size of the traps upwards or downwards, one increases or decreases the chances of the electrons escaping. It is this unexpected analogy that made it possible to make the surprising conclusions about the periodic vaccination protocol that is, to show how targeted, selective vaccination can indeed limit the "escape" of infectious germs and allow the disease to die down through largely a natural process.

Meerson and colleagues have yet to model their periodic vaccination scheme using real-world data. But they say their calculations show that vaccinating just a few percent of the population could reduce the time it takes to eradicate a disease from, say, five months, to between three and four. The researchers hope to continue refining their work on this phenomenon.


'/>"/>

Contact: Jerry Barach
jerryb@savion.huji.ac.il
972-258-82904
The Hebrew University of Jerusalem
Source:Eurekalert  

Related medicine news :

1. Compound enhances cancer-killing properties of agent in trials
2. Proper Foot Care a Must for Patients with Peripheral Arterial Disease
3. Improper use of opioids sparks a new Canadian practice guideline
4. Natural Cayenne Pepper Soap Boasts Anti-Aging Properties for an Instant Facelift
5. New research reinforces anti-inflammatory properties of tart cherries
6. Many Doctors Not Using Colon Cancer Test Properly
7. Adaptogenic Properties of Tahitian Noni Bioactive Beverages Revealed
8. Proper Home Dcor May Assist in Alleviating Back Pain
9. Ensemble Healthcare Properties Purchases North Valley Medical Plaza
10. Simon Property Group Elects Larry Glasscock to Board of Directors
11. Panel: Properly designed pay-for-performance models can support medical professionalism
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
With proper planning, selective rather than mass vaccination can provide immunity against flu
(Date:1/24/2017)... ... January 23, 2017 , ... The Pharmacy and Medically Underserved ... bipartisan original co-sponsorship of nearly one-quarter of the U.S. House of Representatives. The ... Chain Drug Stores (NACDS) strongly backs the legislation. , “NACDS thanks for their ...
(Date:1/24/2017)... ... 23, 2017 , ... The TouchPoint Solution, parent company of ... into the product’s app. The data replicates and validates Co-Founder and Neuropsychologist ... 30 seconds of using Buzzies, people experienced a 74 percent reduction in their ...
(Date:1/23/2017)... York, NY (PRWEB) , ... January 23, 2017 , ... ... announced today that John J. Nelson, a senior accountant at the Firm, will participate ... of Make-A-Wish® Hudson Valley. Over 200 runners will race up 1,576 steps, a vertical ...
(Date:1/23/2017)... FL (PRWEB) , ... January 23, 2017 , ... Wooden and plastic balance boards have ... strength and improve balance. Kumo Board is the first and only balance board ... it to be soft and rigid at the same time as well as skill-level adjustable ...
(Date:1/23/2017)... ... 2017 , ... METTLER TOLEDO has announced the availability of ... PAT Tools . , Crystallization is a common step used during ... Chemists now spend more time developing better intermediate and final crystallization steps. ...
Breaking Medicine News(10 mins):
(Date:1/24/2017)... YORK , Jan. 23, 2017 ... detect, and control light. The interaction of these ... used in a wide range of applications. These ... aerospace and defense, telecommunications, and healthcare among others. ... primarily owing to its low power consumption, reliability, ...
(Date:1/24/2017)... VALLEY COTTAGE, New York , January 23, 2017 ... Projected to Witness Sluggish Growth ... world are derived from formulating Active Pharmaceutical Ingredients (API), ... isopropanol, propanol and propylene glycol. Production of ... Asia-Pacific excluding Japan ...
(Date:1/23/2017)... 2017  Therabron Therapeutics, Inc., a clinical-stage biotechnology ... respiratory care, today announced that the European Medicines ... granted Orphan Drug Designation for Therabron,s CG367 program, ... (BOS).  "We are pleased to have ... treat patients diagnosed with BOS following lung transplantation. ...
Breaking Medicine Technology: