Navigation Links
With Anorexia, Body May Hoard Fat in Bones
Date:2/10/2010

Finding may help explain osteoporosis among those with the eating disorder

WEDNESDAY, Feb. 10 (HealthDay News) -- People with the eating disorder anorexia nervosa have excess levels of fat in their bone marrow, U.S. researchers have found.

The disorder, which affects mainly young women, leads to extremely low body weight and an obsessive fear of weight gain.

"It's counterintuitive that an emaciated young woman with almost no subcutaneous [below the skin] fat would be storing fat in her marrow," lead researcher Dr. Catherine Gordon, an endocrinologist and director of the Bone Health Program at Children's Hospital Boston, said in a hospital news release.

For the study, MRI scans were taken of the knees of 40 girls, who averaged 16 years old -- 20 with anorexia and 20 who were healthy. The girls with anorexia had higher fat content and less than half as much healthy red marrow in their knees, the researchers found. The difference was also seen in the lower thighbone and upper shinbone.

The findings are published in the February issue of the Journal of Bone and Mineral Research.

Earlier studies had found that hormonal changes in malnourished people trigger the bone marrow's mesenchymal stem cells to turn into fat cells rather than bone-forming cells. That could explain why people with anorexia lose bone mass and sometimes develop osteoporosis, the researchers said.

"Bone formation is very low in girls with anorexia, and that's a particular problem because they are growing adolescents who should be maximally forming bones," Gordon said. "But because of the hormonal alterations induced by malnutrition, the bone marrow stops yielding the needed cells to form bone. Instead, the stem cells are pushed toward fat formation."

Gordon plans further studies to find out why this occurs. One theory is that it's due to the body's attempt to store energy and preserve warmth. Because of their lack of insulating fat, people with anorexia often develop extremely low body temperatures (hypothermia) and need to be hospitalized.

More information

The U.S. National Women's Health Information Center has more about anorexia nervosa.



-- Robert Preidt



SOURCE: Children's Hospital Boston, news release, Feb. 8, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Compulsive Hoarding Poses Safety and Psychological Risks
2. New IOF Report Shows Smoking, Alcohol, Being Underweight and Poor Nutrition Harm Our Bones
3. Some Female Athletes Risking Weaker Bones
4. High-Trauma Fractures Tied to Weak Bones
5. Diabetes Drug Avandia Could Weaken Bones
6. Dads break bones of children more often than moms
7. Stem cell treatment for brittle bones in the womb
8. Scientists move towards stem cell therapy trials to mend shattered bones
9. Potential brain cancer drug for children may damage bones
10. Potential Brain Cancer Drug for Children May Damage Bones
11. Good luck indeed: 53 million-year-old rabbits foot bones found
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2016)... ... May 05, 2016 , ... ... Population Management Platform, announced today that Enlightened Solutions has joined the Premier Outcomes-Driven ... optimize the care continuum for their patients being treated for substance use. , ...
(Date:5/5/2016)... ... ... Linfield College Online and Continuing Education is encouraging registered nurses to apply ... for all qualified applicants from May 1–14. Students need only go to the application ... , With the RN to BSN degree program, all core classes ...
(Date:5/5/2016)... ... May 05, 2016 , ... Augusta Public Schools has ... nurses. This partnership will enable school health offices to streamline and bolster care for ... Kansas, just east of Wichita. Augusta public schools serve 2,300 students among its six ...
(Date:5/5/2016)... ... May 05, 2016 , ... BloodHub, the nation’s dominant supply ... Blood suppliers and their hospitals use BloodHub for order management, inventory control, ... across 2,100 hospitals who use our platform to processes thousands of life-saving transactions ...
(Date:5/4/2016)... ... May 04, 2016 , ... ProList is a set ... X . With ProList, editors can easily create lists for presentations, youtube productions, ... additional bullet points. ProList is the perfect complement to presentation style videos. , ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... Inc. (NYSE: DPLO) announced today that it is celebrating Hepatitis Awareness Month with a campaign ... their personal story and encourage those at risk to get tested and begin the road ... ... ... Pharmacy (PRNewsFoto/Diplomat Pharmacy, Inc.) ...
(Date:5/3/2016)... , May 3, 2016  Specialty Silicone Fabricators ... that shows how a cleanroom works. The free ... about science and technology. ... a technology company, SSF enthusiastically supports the Science, ... educators foster the next generation of innovators. We ...
(Date:5/3/2016)... 2016 Global and Chinese ... basic overview of the industry that covers definition, ... mesh report explores into the international and Chinese ... on Surgical Mesh market spread across 150 pages ... figures is available at http://www.reportsnreports.com/reports/470569-global-and-chinese-surgical-mesh-industry-2016-market-research-report.html . ...
Breaking Medicine Technology: