Navigation Links
With Amino Acid Diet, Mice Improve After Brain Injury
Date:12/8/2009

h function together to maintain an appropriate balance of brain activity. Glutamate excites neurons, stimulating them to fire, while GABA inhibits the firing. Too much excitement or, too little, and the brain doesn't work properly. A TBI upsets the balance.

In particular, a TBI frequently damages the hippocampus, a structure deep in the brain involved in higher learning and memory. In the current study, the researchers found that an injury to the hippocampus reduced levels of BCAAs. Although overall levels of glutamate and GABA were unchanged, the loss of BCAAs disturbed the critical balance of neurotransmitters in the hippocampus, making some localized regions more excitable and others less excitable. Cohen's team tested the hypothesis that providing dietary BCAAs would restore the balance in neural response.

In this study, Cohen's study team first created standardized brain injuries in mice, and one week later compared the animals' conditioned fear response to that of uninjured mice. A week after receiving a mild electric shock in a specific cage, normal mice tend to "freeze" when placed in the same cage, anticipating another shock. The brain-injured mice demonstrated fewer freezing responses -- a sign that they had partially lost that piece of learning.

On the other hand, brain-injured mice that received a diet of BCAAs showed the same normal response as the uninjured mice. The BCAA cocktail had restored their learning ability.

In addition to the behavioral results, the team conducted electrophysiological experiments in slices of hippocampus from brain-injured and non-injured mice, and showed that BCAA restored a normal balance of neural activity. "The electrophysiological results were consistent with what we saw in the animals' functional recovery," said Cohen.

If the results in mice can be reproduced in people, patients with traumatic brain injuries could receive the BCAAs in a drink. Cohen suggests that BC
'/>"/>

SOURCE The Children's Hospital of Philadelphia
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Fitness Nutritions Amino Acid Complex Olympic Champion Dara Torres Calls The Best Product Ive Ever Used, Selects TransMedia for PR
2. Acetaminophen May Weaken Effectiveness of Kids Vaccines
3. El Camino Hospital Provides Local Perspective on Health Care Reform and Innovation at Silicon Valley Healthcare CEO Summit
4. Reportlinker Adds Commercial Amino Acids Report
5. Catalyst Pharmaceutical Partners Licenses Exclusive Rights to New Class of GABA Aminotransferase Inhibitors From Northwestern University
6. Docs Say No to Pulling Drugs Containing Acetaminophen off the Market
7. El Camino Hospital Los Gatos Celebrates Opening With the Community
8. Vegetable Amino Acid Lowers Blood Pressure
9. Pain Medicine Experts Recommend Safe and Responsible Use of Acetaminophen
10. FDA Panel Urges Tough Controls on Acetaminophen Painkillers
11. FDA Advisers Urge Smaller Doses of Acetaminophen
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... Providenciales, Turks & Caicos Islands, BWI (PRWEB) August 29, 2014 ... again, Providenciales, the main hub in the Turks & Caicos ... by nabbing the #2 spot as Best Island in the ... website http://www.tripadvisor.com . Every year, travelers from all ... Caicos is more often than not a winner in multiple ...
(Date:8/29/2014)... Canadian Healthy Vending , the largest healthy ... survey of its 200 operators from every region of ... appeal to Canadian consumer seeking refreshment at healthy vending ... five selling healthy snacks and top five selling healthy ... for consumers, employers, and families. Everyone wants to eat ...
(Date:8/29/2014)... Diego, CA (PRWEB) August 29, 2014 ... filed a lawsuit against Pfizer Inc., Greenstone LLC and ... born with congenital birth defects as a result of ... birth defect lawsuit was filed in St. Clair County ... According to the lawsuit, the defendant companies allegedly concealed ...
(Date:8/29/2014)... CA (PRWEB) August 29, 2014 Recent ... have suggested that Americans today are working longer hours ... overworked and overstressed. APEC Water believes that drinking lots ... a Labor Day Sale on their most popular and ... and healthy. From now until 9/2/2014, customers can save ...
(Date:8/29/2014)... August 29, 2014 The Department ... Drug Administration (FDA), Center for Food Safety and ... delivery, indefinite quantity (IDIQ) contract and the first ... and ā€œDevelopment, Modernization and Enhancement (DME) for FARM ... , Overarching contract objectives include:, ...
Breaking Medicine News(10 mins):Health News:Survey Results: What Products Do Canadians Want in Their Healthy Vending Machines? 2Health News:Survey Results: What Products Do Canadians Want in Their Healthy Vending Machines? 3Health News:The Law Office of Melinda J. Helbock A.P.C. Comments on Zoloft Birth Defect Lawsuit 2Health News:Relax this Labor Day Weekend with Great Savings on Easy-Install, Do-It-Yourself Drinking and Whole House Water Filters 2Health News:Team VersaTech and CRGT Win HHS FDA Contract to Support Food Applications Regulatory Management (FARM) System Upgrade 2Health News:Team VersaTech and CRGT Win HHS FDA Contract to Support Food Applications Regulatory Management (FARM) System Upgrade 3
... a region in the brain, previously understood to be a ... finding has revealed that this region is versatile as it ... double up their response to objects- automobiles, animals and even ... in a portion of the brain called the fusiform gyrus ...
... rate of diabetes in pregnancy has increased four times among ... gestational diabetes// may cause problems for babies. In NSW the ... ,Diabetes Australia NSW president Neville Howard said it was ... experienced a change so dramatic that record numbers of pregnant ...
... for Disease Control and Prevention say that mothers who are ... them if they deliver their baby by C-section// rather than ... Birth: Issues in Perinatal Care. For the study researchers looked ... in four years. ,In general, neonatal ( ...
... on the tip that makes them cling to surfaces. The ... coiled// , bungee cord-like structure which helps the bacteria hang ... researchers report in the journal PLoS Biology. ... Seattle and ETH Zurich in Switzerland have been studying how ...
... A study by Karolinska Institutet in Sweden and Makerere University ... placenta of pregnant women// and this is the reason for ... ,Plasmodium falciparium is the worst of the four malaria parasites ... also infects the placenta of pregnant women, with fatal consequences ...
... in the Northeast say that the media is insensitive to ... them// . ,"I have come across journalists ... me, and didn't even look at my eyes during interview ... stigma," said Vanlalmuana, the president of the Positive Network of ...
Cached Medicine News:Health News:Region in the brain in-charge of face recognition includes object recognition as well. 2Health News:Cesarean Section May Increase Infant Mortality Rates in Low-Risk Women 2Health News:Fimbriae Help Bacteria Stick Around Inside the Body 2Health News:Malarial Parasite Hides In Placenta 2
(Date:8/29/2014)... Mass. , Aug. 29, ... PHG AEX: ... the  European Society of Cardiology ... is highlighting the full range of its cardiology solutions serving ... care continuum from prevention and diagnosis, ...
(Date:8/28/2014)... Aug. 28, 2014 Reportlinker.com announces that ... its catalogue: North America Aesthetic Lasers ... http://www.reportlinker.com/p02343466/North-America-Aesthetic-Lasers-and-Energy-Devices-Market-Outlook-to-2020.html North ... to 2020 Summary GlobalData,s new report, ... Outlook to 2020", provides key market data on ...
(Date:8/28/2014)... 28, 2014  Rigrodsky & Long, P.A.: , ... (NYSE: LCI )? , Did you purchase your ... July 16, 2014, inclusive? , Did you lose money ... you want to discuss your rights? ... Attorney, Timothy J. MacFall , announces that a complaint has ...
Breaking Medicine Technology:Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 2Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 3Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 4Philips Spotlights New Cardiology Solutions and Unveils Ultrasound Technology at European Society of Cardiology Congress 2014 5North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 2North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 3North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 4North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 5North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 6North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 7North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 8North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 9North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 10North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 11North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 12North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 13North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 14North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 15North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 16Rigrodsky & Long, P.A. Announces A Securities Fraud Class Action Lawsuit Has Been Filed Against Lannett Company, Inc. 2Rigrodsky & Long, P.A. Announces A Securities Fraud Class Action Lawsuit Has Been Filed Against Lannett Company, Inc. 3
... fourth quarter 2011 earnings release (expected to be issued after ... CVD ) is pleased to invite you to listen ... live over the Internet on Thursday, January 26, 2012 at ... , , Covance Fourth Quarter 2011 Earnings Webcast and Slide ...
... 2012  Yesterday, workers at VPH Pharmacy, a non-retail, pharmaceutical ... the United Food and Commercial Workers (UFCW) Union in ... on the job. The vote ends the workers, nearly ... they stood unmoved and united in their fight. ...
Cached Medicine Technology:
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: