Navigation Links
Wistar-led research team discovers genetic pattern that indicates early-stage lung cancer
Date:12/1/2009

When 18 NSCLC patients had peripheral blood drawn before surgery and again two to five months after their tumors were surgically removed, 13 of the samples showed a decrease in or complete disappearance of the tumor gene signature present in the pre-surgery samples after tumor removal. This finding demonstrates that the tumor presence can be communicated to the peripheral immune system and this signal can be detected in the gene expression patterns in peripheral blood.

Lung cancer is the most commonly occurring cancer in both men and women in the United States, accounting for 162,000 deaths in 2008, more than any other cancer. Early diagnosis followed by surgery presently is the most effective treatment for NSCLC, which accounts for 75 percent of lung tumors. Detecting cancer at its earliest stages would greatly improve the likelihood of survival; however, no simple and accurate screening test such as mammography for breast cancer or colonoscopy for colon cancer exists for lung cancer. In addition, early-stage lung cancers show few symptoms and tend to spread rapidly before they are found.

With further study, the findings may serve as the basis for developing a simpler screening test for lung cancer. "People routinely get blood taken at their doctor's offices, for cholesterol levels, diabetes, and other standard tests, so why not utilize this method to screen for other conditions such as the risk of developing lung cancer?" says Louise Showe, a professor in Wistar's Molecular and Cellular Oncology and Immunology programs and director of its genomics facility. "Such a test could be especially useful for remote areas where typically technologies that are used in urban centers are not available. In addition, this test could be useful in a clinical setting to help to decide whether a small tumor detected on an x-ray is likely to be malignant."

The team is working to develop a simpler method for collecting and processing blood samples fo
'/>"/>

Contact: Staci Vernick Goldberg
sgoldberg@wistar.org
215-898-3716
The Wistar Institute
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. UM Clinical Research Building awarded prestigious LEED Building Certification
2. New Research From EBRI: Consumer-Driven Health Plan Participants Display Cost-Conscious Behavior, Utilize Wellness Programs
3. Targeted Testing Receives Favorable Reviews On PADDS, Begins Nationwide Research Study On The Target Tests of Executive Functioning-OV
4. Research highlights need for national HIV strategy
5. Parent mentors can improve the asthmatic care of minority children, UT Southwestern researchers find
6. Research Report on BioClinica, Inc. as Speculative Buy
7. Research sheds light on workings of anti-cancer drug
8. Dr. Douglas Macmillan Now Providing LUMINEERS at Research Triangle Dental
9. MISSION Skincare(R) Supports GNCs Efforts To Raise Money for St. Jude Childrens Research Hospital(R)
10. Researchers identify proteins in lung cancer cells that may provide potential drug targets
11. Researchers Identify Possible Causative Mutation for Crohn's Disease: Crohn's & Colitis Foundation Annual Conference to Present Emerging Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... December 25, 2014 Epigenetics finds applications ... research, including oncology, drug discovery, developmental biology, and research ... as one of the most widely used techniques for ... GLOBOCAN, the prevalence of cancer is rapidly growing worldwide. ... 8.2 million cancer deaths, and 32.6 million people living ...
(Date:12/24/2014)... 24, 2014 Dr. Vu Ho, a ... of his practice and med-spa with the addition of ... list of cosmetic treatments and services. , “Silk Peel ... skin,” says Dr. Ho. “As a result it can ... wrinkles, sun spots, discolorations or blemishes.” , Similar to ...
(Date:12/24/2014)... 24, 2014 Mike Billings , ... with Derek Fenwick, PT, MBA, GCS, Director of ... stem from the passing of the Improving Medicare ... In this taping of the Infinicast, the two leaders ... the Social Security Act to standardize post-acute assessment data ...
(Date:12/24/2014)... 24, 2014 (HealthDay News) -- A new, injectable weight-loss ... Drug Administration. The agency on Tuesday approved Saxenda ... who are overweight and have at least one weight-related ... diabetes or high cholesterol. Patients taking the drug, ... diet and exercise regularly, the FDA noted. "Obesity ...
(Date:12/24/2014)... Steven Reinberg HealthDay Reporter ... from the American Diabetes Association (ADA) call for giving the ... to help prevent heart disease. These new standards bring ... and American Heart Association, which also recommend giving low- or ... including people with diabetes. "We agree that the decision ...
Breaking Medicine News(10 mins):Health News:Global Epigenetics Market Was Valued at $413.24 Million in 2014 - New Research Report by MarketsandMarkets 2Health News:Global Epigenetics Market Was Valued at $413.24 Million in 2014 - New Research Report by MarketsandMarkets 3Health News:Dr. Vu Ho Expands Facial Plastic Surgery Practice to Include New Skin Care Treatment 2Health News:Latest Episode of Infinicast Features Infinity Rehab President Discussing IMPACT Act of 2014 and Changes for Post-Acute Therapy Providers in 2015 2Health News:FDA Approves New Weight-Loss Drug 2Health News:FDA Approves New Weight-Loss Drug 3Health News:Nearly All Diabetics Should Be on Cholesterol-Lowering Drugs: Experts 2Health News:Nearly All Diabetics Should Be on Cholesterol-Lowering Drugs: Experts 3
... Aug. 13 As the debate over health care reform heats up, ... district has been, well, blunted. , , The billboard ... Blunt has taken $556,682 in contributions from the insurance industry. Is that ... , USAction and its Missouri affiliate, Missouri Progressive Vote Coalition, ...
... sexual assault and seeking help is difficult for anyone, but ... (LGBTQ) the thought of reporting a crime may well be ... a study in Oregon. The study, appearing in the ... found that 94 percent of respondents -- most of them ...
... , , , ... care industry moves from paper-based to electronic record-keeping, protecting confidential ... issue, Verizon is unveiling two new capabilities designed to help ... clinics, physicians, insurers and patients. , , ...
... , TORONTO, Aug. 13 /PRNewswire-FirstCall/ - Patheon Inc. (TSX: ... services to the global pharmaceutical industry, announced today that ... on Monday, September 14, 2009. , In conjunction with ... financial analysts on Monday, September 14, 2009 at 10:00 ...
... TOSU, SAGA, Japan, Aug. 13 Hisamitsu Pharmaceutical Co., Inc. ... announced the expiration of the waiting period under the Hart-Scott-Rodino Antitrust ... p.m., New York City time, on August 12, 2009, with respect ... NOVN ). , , ...
... Medical Research Council (MRC) scientists have made an important advance ... to die. The work may help scientists to eventually develop ... occur when cell death goes wrong. The research, published ... 14 August 2009) was carried out by a team of ...
Cached Medicine News:Health News:Blunted by Roy Blunt: The Billboard the Congressman Doesn't Want You to See 2Health News:Little safe haven for sexually assaulted LGBTQ victims 2Health News:Little safe haven for sexually assaulted LGBTQ victims 3Health News:Verizon Introduces New IT Security Capabilities for Health Care Industry 2Health News:Verizon Introduces New IT Security Capabilities for Health Care Industry 3Health News:Verizon Introduces New IT Security Capabilities for Health Care Industry 4Health News:Patheon Announces Date of Third Quarter 2009 Financial Results Release, Conference Call and Webcast 2Health News:Hisamitsu Pharmaceutical Announces Expiration of HSR Waiting Period for Its Proposed Acquisition of Noven Pharmaceuticals 2Health News:MRC scientists advance understanding of cell death 2
(Date:12/22/2014)... 22, 2014 NxStage Medical, Inc. (NASDAQ: ... dialysis products, announced today that the U.S. Food ... One™ to perform hemodialysis overnight while the patient ... hemodialysis. NxStage,s® System One is the first and ... this indication. Home nocturnal hemodialysis ...
(Date:12/22/2014)... 22, 2014   TRU-D SmartUVC LLC, producers ... robot, announced today that the General Services Administration has ... 2019.   This newly formed agreement will ... of government purchasers, including Department of Veteran Affairs and ... Security contacts purchasing solutions for the Ebola effort in ...
(Date:12/22/2014)... , Dec. 22, 2014 Cyberonics, Inc. (NASDAQ: ... the treatment and management of epilepsy, today announced it will ... Conference on Wednesday, January 14, 2015, in San ... President and Chief Executive Officer, will speak at 11:00 AM ... be accessed by clicking on the Investor Relations link on ...
Breaking Medicine Technology:NxStage Receives FDA Clearance for Home Nocturnal Hemodialysis 2NxStage Receives FDA Clearance for Home Nocturnal Hemodialysis 3TRU-D SmartUVC LLC Awarded General Services Administration Contract to Expand Government Customer Base 2
... March 5, 2012 Medical Care Technologies Inc. ... Special Meeting of Shareholders of the Company,s common stock held ... for lack of quorum. The adjourned Special Meeting will occur ... to provide time for the shareholders to ensure that their ...
... Wash., March 5, 2012  SCOLR Pharma, Inc. (OTCQB: SCLR) ... product information and "where to buy" details for their ... available retailers can be found on www.scolr.com ... page can be reached from the home page or ...
Cached Medicine Technology:Medical Care Technologies Inc. Announces Adjournment of Special Meeting 2Medical Care Technologies Inc. Announces Adjournment of Special Meeting 3SCOLR Pharma, Inc. Provides Product Information on Website 2
... A fixed pipette is ideal ... single volume. Fixed volume FInnpipettes ... advantages as other Finnpipette Digital ... Super blow-out (1-40ul), Soft-touch tip ...
10L...
... and value!, Comfortable feel and ... contoured handle , Finer control while ... action , Completely autoclavable for easy ... for recalibration , Easy-to-read precision micrometer ...
... 2000 Pipette is a synonym for pipetting ... robust design, and superior operating comfort. Its ... the measuring stroke and blow-out as well ... system ensures utmost accuracy and precision. Ejection ...
Medicine Products: