Navigation Links
Will women use microbicides to protect themselves against HIV?
Date:4/19/2012

PROVIDENCE, R.I. Are women willing to use a vaginal gel to protect themselves against HIV infection? Researchers at The Miriam Hospital say that is the million dollar question when it comes to developing products known as microbicides that can prevent the sexual transmission of HIV.

Now the findings of a new study known as Project LINK could offer critical insight on user experience with topical vaginal gels information that could be used to develop microbicide products that optimize a woman's experience, ultimately leading to more consistent use.

Miriam researchers, led by psychologist Kathleen M. Morrow, Ph.D., examined how the formulation of a microbicide particularly the properties and characteristics of the gel itself relates to user experience. This information was used to show the range of different sensations and experiences reported by women when they use vaginal gels.

The findings were presented on April 17 at the International Microbicides Conference in Australia.

"Adherence and acceptability have been major challenges so far with microbicides," said Morrow. "But if we can develop a product that delivers an effective drug that reduces HIV infections and it's something that women can tolerate if not enjoy then the microbicide will have a greater impact on the HIV epidemic."

"It's incredibly important that scientists and microbicide developers hear the voice of potential microbicide users so they can use that information to make the best prevention products possible," she added. "That's how we will begin to have a fighting chance at stemming the tide of HIV and AIDS."

Microbicides are compounds in various topical forms, such as gels, creams, films and rings, that deliver specific drugs that protect against HIV and other sexually transmitted diseases. Although a safe and effective microbicide has not yet been identified, a number of different microbicides are currently in development.

Half of the estimated 34 million adults worldwide living with HIV and AIDS are women. Women are twice as likely as men to acquire HIV from unprotected sex, but they remain dependent on male cooperation to protect themselves from infection. Microbicides represent an HIV prevention method that women can control, which could be critical in cultures where women may have less power to say "no" to sex, have difficulties negotiating condom use with their partners, and are more likely to be subjected to non-consensual sex. This need is especially urgent in Africa, where AIDS is the leading cause of death and women are disproportionally affected by the disease.

As part of Project LINK, 204 participants experienced four gels, rated how each felt and indicated which formulation they would prefer. Researchers found that preferences varied among the participants, and users' experiences seemed to impact the product they chose, with different women choosing different products. For example, while some women preferred a thicker consistency, others preferred gels that were more lubricating.

They found women do indeed have very specific experiences when using vaginal gels and they can discriminate between different gels based on properties such as texture or consistency. These experiences also impacted women's preferred product choice. Researchers were then able to use this information to develop tools to show the range of different sensations and experiences reported by women when they use vaginal gels.

Morrow said these user sensory perception and experience measures could help predict which properties play a role in the decision to use a product. That information could then be harnessed to design better microbicides that people will use consistently, she added.

"There is no other research group that I know of that is taking this approach to both understand the user experience and use that understanding to develop very specific biomedical HIV prevention formulations or devices," said Morrow. "It's not that such experiences are not considered in the development of microbicides, but we are doing so very early in the process, before any clinical trials."


'/>"/>

Contact: Jessica Collins Grimes
jgrimes2@lifespan.org
401-793-7484
Lifespan
Source:Eurekalert

Related medicine news :

1. Research shows efficacy of treatment model developed at Women & Infants
2. Women With Older Partners More Often Admitted to Nursing Homes
3. Overweight Pregnant Women at Higher Risk for Complications
4. Women Less Apt Than Men to Get Recommended Daily Exercise
5. Stress contributes to cognitive declines in women with breast cancer, researcher says
6. White Women Make Up Bulk of Assisted-Living Residents
7. Timing pregnancy an important health concern for women
8. Study: Women not getting enough exercise; at risk of developing metabolic syndrome
9. Obese White Women Shying Away From Colon Cancer Screening
10. 62 percent of men and 37 percent of women over the age of 65 are sexually active
11. Taller, Heavier Women May Face Higher Ovarian Cancer Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) ... a collection of specialty vendors and unique items from across the nation, this holiday-themed ... and wellness services offered by the VNA. The boutique will be open Saturday, ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and fastest ... to open a flagship location in Covington, LA at 401 N. U.S. Highway 190, ... next to Office Depot in the Holiday Square shopping center. Its location allows it ...
(Date:10/12/2017)... ... October 12, 2017 , ... Information ... we intend to develop to enable prevention of a major side effect of ... loss, especially in pediatric patients. For cisplatin, hearing loss is FDA listed on-label ...
(Date:10/12/2017)... ... October 12, 2017 , ... Women-owned ... Michigan’s 2017 Best and Brightest in Wellness® by Best and Brightest. OnSite Wellness ... on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. at the Henry ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... ZirMed Inc ., a recognized leader in cloud-based revenue cycle ... ranked #1 by its users for the seventh consecutive year ... ZirMed was recognized as the top-ranked end-to-end revenue cycle management ... 200 beds and holds one of the longest #1 ranking ... ...
(Date:9/13/2017)... ATLANTA , Sept. 13, 2017   OrthoAtlanta ... to the Atlanta Football Host Committee (AFHC) for the 2018 ... Monday, Jan. 8, 2018, at Mercedes-Benz Stadium in ... part of the AFHC "I,m In" campaign, participating in many ... ...
(Date:9/12/2017)...  ValGenesis Inc., the global leader in Enterprise ... announce the appointment of Dr. Ajaz Hussain ... Directors and Chairman of Advisory Board beginning September ... to manage their entire validation lifecycle process electronically ... process. Furthermore, ValGenesis VLMS enables rigorous compliance, helps ...
Breaking Medicine Technology: