Navigation Links
Why you remember names and ski slopes
Date:11/21/2007

CHICAGO --- When you meet your boss's husband, Harvey, at the office holiday party, then bump into him an hour later over the onion dip, will you remember his name?

Yes, thanks to a nifty protein in your brain called kalirin-7.

Researchers at Northwestern University's Feinberg School of Medicine have discovered the brain protein kalirin is critical for helping you learn and remember what you learned.

Previous studies by other researchers found that kalirin levels are reduced in brains of people with diseases like Alzheimer's and schizophrenia. Thus, the discovery of kalirin's role in learning offers new insight into the pathophysiology of these disorders.

"Identifying the key role of this protein in learning and memory makes it a new target for future drug therapy to treat or delay the progression of these diseases," said Peter Penzes, lead author of the study and assistant professor of physiology at the Feinberg School. Penzes studied the brains of laboratory rats which are similar to human brains.

The study will be published November 21 in the journal Neuron.

Kalirin behaves like a personal trainer for your memory. When you learn something new, kalirin bulks up the synaptic spines in your brain -- which resemble tiny, white mushrooms. The spines grow bigger and stronger the more you repeat the lesson. It works the same whether you're learning a new cell phone number, skiing a new double black diamond slope or testing a pumpkin cheesecake recipe.

Synaptic spines are the sites in the brain where neurons (brain cells) talk to each other. "If these sites are bigger, the communication is better," Penzes said. "A synapse is like a volume dial between two cells. If you turn up the volume, communication is better. Kalirin makes the synaptic spines grow."

Kalirin's role in learning and memory help explain why continued intellectual activity and learning delays cognitive decline as people grow older. "It's important to keep learning so your synapses stay healthy," Penzes said.


'/>"/>

Contact: Marla Paul
Marla-Paul@northwestern.edu
312-503-8928
Northwestern University
Source:Eurekalert

Related medicine news :

1. Alzheimers Foundation of America to Display Quilt to Remember in Los Angeles
2. ResMed Names Kieran Gallahue as Chief Executive Officer, Effective January 1, 2008.
3. Mediware Names Thomas K. Mann Chief Executive Officer
4. Cleveland-based Health Care Tech Company Within3 Names New CEO
5. STERIS Corporation Board of Directors Names Walter M. Rosebrough Jr. President and Chief Executive Officer
6. Patient Safety Authority Board of Directors Names Infection Advisory Panel
7. Hooper Holmes Names Chris Behling President of Health & Wellness Division
8. MDMA Names New Director of Federal Affairs
9. Milestone Scientific Names Robert Presutti New Vice President of Sales and Marketing
10. Acuo Technologies(R) Names Mike Dolan Vice President of Sales
11. MAKO Surgical Corp. Names Frederic H. Moll, M.D. to Board of Directors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... 2016 , ... TherapySites, the leading website and ... Tennessee Counseling Association. This new relationship allows TherapySites to continue to extend ... exclusive benefits and promotional offers. , "TCA is extremely excited about this new ...
(Date:6/26/2016)... ... 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic treatment ... Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. This ... of the world’s leading providers of cereal and other breakfast foods. Its residents often ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, ... work on several important health care topics including advance care planning, healthcare costs ...
(Date:6/25/2016)... ... 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his ... David Geffen School of Medicine at UCLA. He trained in Internal Medicine at Scripps ... in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to ...
(Date:6/24/2016)... Marne, Michigan (PRWEB) , ... June 24, 2016 , ... ... To deal with these feelings, many turn to unhealthy avenues, such as drug or ... Center of Marne, Michigan, has released tools for healthy coping following a traumatic event. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 23, 2016 Roche (SIX: RO, ROG; OTCQX: ... its Elecsys BRAHMS PCT (procalcitonin) assay as a dedicated ... shock. With this clearance, Roche is the first IVD ... solution for sepsis risk assessment and management. ... and PCT levels in blood can aid clinicians in ...
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on ... today announced that patient enrollment in its ongoing ... Duchenne) has exceeded 50% of its 24-patient target. ... in the third quarter of 2016, and to ...
(Date:6/23/2016)... , June 23, 2016 Bracket , a ... its next generation clinical outcomes platform, Bracket eCOA (SM) ... on June 26 – 30, 2016 in Philadelphia ... electronic Clinical Outcome Assessment product of its kind to fully ... Bracket eCOA 6.0 is a flexible platform for ...
Breaking Medicine Technology: