Navigation Links
Why good resolutions about taking up a physical activity can be hard to keep
Date:1/4/2013

ive ingredient of cannabis), and physical exercise. It was discovered ten years ago that physical exercise activated the endocannabinoid system in trained sportsmen, but its exact role remained a mystery for many years. Three years ago, the same research team in Bordeaux observed that when given the opportunity to use a running wheel, mutant mice lacking the CB1 cannabinoid receptor, which is the principal receptor of the endocannabinoid system in the brain, ran for a shorter time and over shorter distances than healthy mice. The research published in Biological Psychiatry this month seeks to understand how, where and why the lack of CB1 receptor reduces voluntary exercise performance (by 20 to 30%) in mice allowed access to a running wheel three hours per day.

The researchers used various lines of mutant mice for the CB1 receptor, together with pharmacological tools. They began by demonstrating that the CB1 receptor controlling running performance is located at the GABAergic nerve endings. They went on to show that the receptor is located in the ventral tegmental area of the brain (see diagram below), which is an area involved in motivational processes relating to reward, whether the reward is natural (food, sex) or associated with the consumption of psychoactive substances.

Based on the results of this study and earlier work, the Bordeaux team suggests the following neurobiological explanation: at the beginning and for the duration of physical exercise, the CB1 receptor is constantly simulated by the endocannabinoids, lipid molecules that naturally activate this receptor in response to pleasant stimuli (rewards) and unpleasant stimuli (stress). Endocannabinoid stimulation of the CB1 receptor during physical exercise inhibits the release of GABA, an inhibitory neurotransmitter that controls the activity of the dopamine neurons associated with the motivation and reward processes. This stimulation of the CB1 receptor "inhibits inhibition",
'/>"/>

Contact: Press Office
presse@inserm.fr
INSERM (Institut national de la sant et de la recherche mdicale)
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Brain Spade Announces Site Launch is Now Set for January – New Year’s Resolutions Now Include Brain Health and Fitness
2. Boot Camp Classes for 2013 New Year’s Eve Resolutions!
3. The Spencer Institute Supports New Year’s Resolutions and Long-Term Health with Wellness Coach Certification
4. Time for New Year’s Resolutions, Add Better Tax Records to the List
5. Resolutions Don’t Work—But It’s NOT Because You Suck. How To Rock-It in 2013 with Vicki Dello Joio
6. EZ Wellness Extends HCG Sale to Aid New Years Resolutions For Weight Loss
7. VetDepot Encourages Owners to Include Pets in New Year’s Resolutions
8. New Years and Old Resolutions: Smart Vitamin Club Sees Ripple Effect of Health Resolutions
9. What can Hollywood teach us about our planet?
10. Stress about wifes breast cancer can harm a mans health
11. Concerns about MRSA for expectant mothers may be unfounded
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/29/2015)... ... June 29, 2015 , ... National ... auditor of customer service for the 40-center nursing home group. Sixteen of their ... centers in the United States in one or more customer service areas. Those ...
(Date:6/29/2015)... ... June 29, 2015 , ... Scientists from ... to build nearly complete genomes by combining high-throughput DNA sequencing with genome mapping. ... for their association with human disease, but previously difficult to detect. The study ...
(Date:6/29/2015)... ... 2015 , ... With Urgent Care Medicine now serving a vital role in ... Urgent Care Medicine and the Medical Society of Delaware to provide its latest professional ... health care professionals. , According to Matthew Bader, Exam Master CEO and President, “This ...
(Date:6/29/2015)... ... 29, 2015 , ... USA Today reported on June 18th the ... Alabama. To impact the rest of the nation’s growing overdose death rates in 26 ... guidelines be followed to stop the increasing overdose trend from continuing: , ...
(Date:6/29/2015)... , ... June 29, 2015 , ... OR Manager announced ... revitalized look and feel, as well as a redesigned logo and weekly eLetter. The ... but is now more user-friendly and easier to navigate. , In addition to ...
Breaking Medicine News(10 mins):Health News:National HealthCare Centers Receive 'Customer Experience Awards' 2Health News:National HealthCare Centers Receive 'Customer Experience Awards' 3Health News:National HealthCare Centers Receive 'Customer Experience Awards' 4Health News:Mount Sinai Scientists Develop New Approach for More Accurate and Comprehensive Whole Genome Assembly, Variant Discovery and Interpretation 2Health News:Mount Sinai Scientists Develop New Approach for More Accurate and Comprehensive Whole Genome Assembly, Variant Discovery and Interpretation 3Health News:Mount Sinai Scientists Develop New Approach for More Accurate and Comprehensive Whole Genome Assembly, Variant Discovery and Interpretation 4Health News:Exam Master Partners to Provide New Urgent Care Continuing Medical Education Resource 2Health News:Exam Master Partners to Provide New Urgent Care Continuing Medical Education Resource 3Health News:Overdose Death Rates Decreased in Florida as of 2015 2Health News:Overdose Death Rates Decreased in Florida as of 2015 3Health News:OR Manager Launches New Website 2
... , BROOKFIELD, Wis., July 21 ... has achieved Premier Certification from Cisco(R). To earn Premier ... service, support and customer satisfaction set forth by Cisco. ... to integrate Cisco,s high-caliber technology into our healthcare safety and ...
... with air pollution, smoking, it raises chances of condition, study ... from cars can increase a child,s chances of developing asthma, ... even higher, a new study finds. , For children exposed ... parental stress also increases the risk for asthma, the researchers ...
... , , ST. PAUL, Minn., ... Paul, MN announces that it has been awarded the Charities Review ... of its Accountability Standards. , , ... Syndrome (MOFAS) earn the Seal by voluntarily participating in the Council,s ...
... , STEWARTVILLE, Minn., July 21 , ... announce quarterly results after financial markets close on Thursday July 30, 2009. ... report. The call will begin at 3:30 p.m. central time (4:30 p.m. ... webcast by Thomson/CCBN and can be accessed at Rochester Medical,s website at ...
... How bold transportation policies can make all communities ... OAKLAND, Calif., July 21 The $450 billion federal transportation bill being debated ... get around for decades to come. But a new report by PolicyLink ... -- done right --- could make millions of Americans healthier and cut down ...
... July 21 The New Jersey Dietetic ... the Year Award for her achievements since becoming a registered dietitian (RD) ... account supervisor in the Food & Well-Connected Practice at Ketchum, a global ... May 8, where she was also featured in a panel discussion, "RDs ...
Cached Medicine News:Health News:RF Technologies Achieves Premier Certification From Cisco in United States 2Health News:Parental Stress Boosts Kids' Asthma Risk 2Health News:Parental Stress Boosts Kids' Asthma Risk 3Health News:Minnesota Organization on Fetal Alcohol Syndrome Earns Charities Review Council 'Meets All Standards' Seal 2Health News:Rochester Medical Announces Third Quarter 2009 Earnings Conference Call July 30, 2009 2Health News:Smart Ideas at the Intersection of Transportation, Health, and Equity 2Health News:Smart Ideas at the Intersection of Transportation, Health, and Equity 3Health News:Smart Ideas at the Intersection of Transportation, Health, and Equity 4Health News:New Jersey Dietetic Association Names Ketchum's Jaime Schwartz Young Dietitian of the Year 2Health News:New Jersey Dietetic Association Names Ketchum's Jaime Schwartz Young Dietitian of the Year 3
(Date:6/29/2015)... 2015 The global insulin market ... a new study by Grand View Research, Inc. Growing global prevalence ... high unmet needs in emerging markets such as India ... be two of the most significant growth drivers of this market. ... and growing global geriatric population base are expected to serve the ...
(Date:6/29/2015)... 29, 2015  VisionCare Ophthalmic Technologies, Inc. ... devices for the treatment of age-related macular ... "Long-Term (60-month) Results for the Implantable Miniature ... Age in Patients with End-Stage Age-Related Macular ... 5-year data show substantial retention of gains ...
(Date:6/29/2015)... Corporates today are on the ... CSR funds effectively.  A genuine step towards improving the ... would definitely interest them. And to make this possible, ... (MSC) to promote experiential learning.  STEM Learning is a ... India . So far, they have ...
Breaking Medicine Technology:Insulin Market To Reach $47.54 Billion By 2020: Grand View Research, Inc. 2Insulin Market To Reach $47.54 Billion By 2020: Grand View Research, Inc. 3Insulin Market To Reach $47.54 Billion By 2020: Grand View Research, Inc. 4Five-Year Data Demonstrates Long Term Effectiveness and Safety of VisionCare's Telescope Implant for Macular Degeneration in Patients 65 Years and Older 2Five-Year Data Demonstrates Long Term Effectiveness and Safety of VisionCare's Telescope Implant for Macular Degeneration in Patients 65 Years and Older 3Five-Year Data Demonstrates Long Term Effectiveness and Safety of VisionCare's Telescope Implant for Macular Degeneration in Patients 65 Years and Older 4Five-Year Data Demonstrates Long Term Effectiveness and Safety of VisionCare's Telescope Implant for Macular Degeneration in Patients 65 Years and Older 5Thinking of Innovative CSR Options? Partner With STEM Learning to Sponsor a Mini Science Centre 2Thinking of Innovative CSR Options? Partner With STEM Learning to Sponsor a Mini Science Centre 3
... $500 Million Senior Notes Offering in Connection With Agreement to... -- ARDEE, Ireland, Sept. 24 ... ... lpUnit=,PRN,; --> ... { var s = ,; var first_result; // Results are keyed by longUrl, so we need to ...
... 24 Stereotaxis, Inc. (Nasdaq: STXS ) today ... JMP Securities Healthcare Conference on Tuesday, September 28, 2010 at ... Officer, will provide an overview of the Company,s business strategy ... conference is by invitation only. A live audio and slides ...
Cached Medicine Technology:Warner Chilcott Announces $500 Million Senior Notes Offering in Connection With Agreement to Acquire U.S. Rights to Enablex® 2Warner Chilcott Announces $500 Million Senior Notes Offering in Connection With Agreement to Acquire U.S. Rights to Enablex® 3Warner Chilcott Announces $500 Million Senior Notes Offering in Connection With Agreement to Acquire U.S. Rights to Enablex® 4Warner Chilcott Announces $500 Million Senior Notes Offering in Connection With Agreement to Acquire U.S. Rights to Enablex® 5Warner Chilcott Announces $500 Million Senior Notes Offering in Connection With Agreement to Acquire U.S. Rights to Enablex® 6Warner Chilcott Announces $500 Million Senior Notes Offering in Connection With Agreement to Acquire U.S. Rights to Enablex® 7Warner Chilcott Announces $500 Million Senior Notes Offering in Connection With Agreement to Acquire U.S. Rights to Enablex® 8Warner Chilcott Announces $500 Million Senior Notes Offering in Connection With Agreement to Acquire U.S. Rights to Enablex® 9Stereotaxis to Present at the JMP Securities Healthcare Conference 2Stereotaxis to Present at the JMP Securities Healthcare Conference 3
Our 2.5v Ophthalmoscope Sets feature high-quality instruments, handles, and cases....
3.5v Ophthalmic Diagnostic Set with AutoStep Coaxial Ophthalmoscope, Spot Retinoscope, Rechargeable Handle, and Soft Case. High-quality eyecare from the preferred name in diagnostic instruments....
... are standard in all Welch Allyn ... students, the 18335-SDS combines the superior ... the superior illumination of the Halogen ... of the Finnoff Transilluminator, and the ...
High-quality eyecare from the preferred name in diagnostic instruments....
Medicine Products: