Navigation Links
Why cancer rate increases with age (it's not what you think)
Date:7/2/2012

mutations was key to avoiding cancer, we'd be better at it than we are."

And finally, if these oncogenes were the evil super-villains they've been made out to be, capable of taking over surrounding tissue, then introducing oncogenes into mice stem cells should help rather than hurt these cells' survival. "Rather, stem cells harboring the oncogenes tend to get weeded out," says DeGregori.

Instead of gathering mutations until they give us cancer, DeGregori says that as we age, the mechanisms that younger adults use to fight cancer, deteriorate.

"It's like what happened to the dinosaurs 65 million years ago," DeGregori says. "Dinosaurs were great and they weren't changing that fast they were well adapted to their landscape. Until that darn meteor. Suddenly what was fit was no longer fit. The species didn't have to change their mutation rate it was the new landscape that drove speciation. Similarly, what primarily drives cancer rates higher as we age is the changed landscape."

Our healthy cells are optimized for the conditions of our healthy, younger tissue. Change this balance, as does an oncogenic mutation, and they're no longer a perfect fit for the surroundings healthy cells in young bodies quickly outcompete cells with cancerous mutations.

But, "when tissue is old, healthy cells are no longer a perfect fit, and mutations might help a cancer cell adapt in ways a healthy cell can't," DeGregori says.

Blot out the sun with a meteor's cloud of dust and mammals will eventually outcompete thunder lizards; age tissue past the expiration date evolution's set and cancer cells can outcompete their normal but aged peers.


'/>"/>

Contact: Garth Sundem
garth.sundem@ucdenver.edu
University of Colorado Denver
Source:Eurekalert

Page: 1 2

Related medicine news :

1. The prevention of hereditary breast and ovarian cancer by PGD is feasible
2. Coffee consumption inversely associated with risk of most common form of skin cancer
3. Potential treatment target identified in an animal model of pancreatic cancer
4. Study finds new gene mutations that lead to enlarged brain size, cancer, autism, epilepsy
5. Accelerated radiation treatment effective for noninvasive breast cancer
6. Specialized MRI scans assess value of anti-cancer chemotherapy long before tumors shown to shrink
7. Actos Bladder Cancer Lawsuit Filed in Louisiana Alleging Woman Used Diabetes Medication and Contracted Bladder Cancer, Consumer Justice Foundation Reports
8. Scientists identify new cancer stem cell mechanism
9. NIH, DOD grants to fund prostate cancer, diabetes research at UH
10. New treatment protocol extends survival in some cases of once inoperable pancreatic cancer
11. Novel radiation therapy safely treats prostate cancer and lowers the risk of recurrence
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... Beach, FL (PRWEB) July 22, 2014 ... that they are now an authorized Daikin comfort pro ... and install Daikin indoor heating and cooling system equipment. ... each one is thoroughly reviewed before being approved. , ... an innovator in the Split System Air Conditioning Market. ...
(Date:7/22/2014)... 22, 2014 The 2014 Warrior-Family ... Ronald Reagan Building and International Trade Center in ... Families and Civilian Communities,” will be held from ... 7:30 a.m.) and cohosted by the Military Officers ... Industrial Association (NDIA). USAA is the Executive Sponsor ...
(Date:7/22/2014)... New York, NY (PRWEB) July 22, 2014 ... ( http://www.xareltolawsuitcenter.com/ ) that alleges the death ... bleeding caused by the blood thinner, Bernstein Liebhard LLP ... the U.S. District Court for the Southern District ... Xarelto in January 2012, and suffered a subdural hemorrhage ...
(Date:7/22/2014)... American Society of Hematology (ASH) will honor Tomas Ganz, ... Angeles with the 2014 E. Donnall Thomas Lecture for ... of the iron-regulatory hormone hepcidin and investigation of its ... Nobel Prize Laureate and past Society president E. Donnall ... have represented a paradigm shift or significant discovery in ...
(Date:7/22/2014)... of the Clean Plate Club you eat pretty much ... A new Cornell University study shows that the average ... his or her plate. "If you put it ... Wansink Ph.D., author of the forthcoming book, Slim by Design, ... Brand Lab. , Wansink and co-author Katherine Abowd Johnson analyzed ...
Breaking Medicine News(10 mins):Health News:Air Conditioning & Heating Inc. Now an Authorized Daikin Comfort Pro Dealer 2Health News:2014 Warrior-Family Symposium Focuses on Transitioning Forward 2Health News:2014 Warrior-Family Symposium Focuses on Transitioning Forward 3Health News:Xarelto Lawsuit Filed by Florida Woman Alleges Uncontrollable Bleeding Led to Husband’s Death, Bernstein Liebhard LLP Reports 2Health News:Xarelto Lawsuit Filed by Florida Woman Alleges Uncontrollable Bleeding Led to Husband’s Death, Bernstein Liebhard LLP Reports 3Health News:Tomas Ganz, M.D., Ph.D., to present 2014 ASH E. Donnall Thomas Lecture 2Health News:Tomas Ganz, M.D., Ph.D., to present 2014 ASH E. Donnall Thomas Lecture 3
... babies of mother's with hypothyroidism are likely to ... hormones which control metabolism, growth and development. Symptoms ... ,Children born with an underactive thyroid ... the condition are more prone to a potentially ...
... supplements are often used by body builders, and there's some ... maintain muscle in older people? One new study indicates the ... 33 men aged 60 to 84 who had similar lifestyles ... training program. Half were given creatine and half were given ...
... not likely to get prostate cancer than men with other ... your blood group affects your health.// In particular, men with ... develop prostate cancer and to get more aggressive forms of ... men who have type A, but not confirmed as yet. ...
... bowel cancer. Research carried out by doctors at Oxford University ... that it reacts with acid in the stomach to prevent ... studied bowel cancer rates in 28 countries across the world, ... disease in the UK, the USA, Brazil, Colombia, Canada and ...
... difficulty digesting milk products may experience an increase in ... a meal replacement. //About 25% of Americans have lactose ... sufficient supply of an intestinal enzyme critical for the ... can cause such individuals to experience bloating, diarrhoea and ...
... stimulant in day to day life. According to researchers drinking ... the day progresses. During the morning hours, memory is ... For researchers at the University of Arizona have found that ... ,They had about 60-70 participants aged over 64 ...
Cached Medicine News:
(Date:7/22/2014)... 22, 2014 BiologicTx ® today announced ... 3-way Kidney Paired Donation transplant exchange utilizing BiologicTx,s proprietary ... July 9 at the Miami Transplant Institute, located at ... Kidney Paired Donation (KPD) is ... for kidney transplant with one another due to incompatible ...
(Date:7/22/2014)...  A central New York ... Total Artificial Heart implant is home, discharged from ... Freedom® portable driver to wait for a matching ... from a Syracuse architectural hardware company, suffered from ... medications, an implantable defibrillator and a pacemaker. ...
(Date:7/22/2014)... -- Halozyme Therapeutics, Inc. (NASDAQ: HALO ) today ... patients in its ongoing Phase 2 trial (Study 202) ... revised clinical protocol agreed to with the FDA in ... proprietary recombinant human hyaluronidase under development for the systemic ... "Our diligent effort to rapidly re-initiate patient enrollment and ...
Breaking Medicine Technology:BiologicTx Paired Donation Aids In Successful Kidney Transplants 2BiologicTx Paired Donation Aids In Successful Kidney Transplants 3'I'm a Heartless SOB' Jokes Patient Discharged from Strong Memorial Hospital without a Human Heart 2'I'm a Heartless SOB' Jokes Patient Discharged from Strong Memorial Hospital without a Human Heart 3Halozyme Resumes Patient Enrollment And Dosing In PEGPH20 Clinical Program In Pancreatic Cancer 2Halozyme Resumes Patient Enrollment And Dosing In PEGPH20 Clinical Program In Pancreatic Cancer 3
... RIDGEFIELD, Conn., Oct. 24, 2011 Apelon, ... data interoperability solutions, today announced the availability ... solution. TermManager, a code set management and ... interoperability initiatives by enabling widespread access to ...
... Codexis, Inc. (Nasdaq: CDXS ) ... Codex® Screening Kits are in use or evaluation ... worldwide.  The announcement was made at CPhI  Worldwide, ... week.   Codex® Screening Kits were ...
Cached Medicine Technology:Apelon Announces Availability of New TermManager® Software 250 Pharma Companies Worldwide Now Use Codexis In Process Development 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: