Navigation Links
Why Some People Live to 110

SUNDAY, Jan. 8 (HealthDay News) -- People who live 110 years or longer have as many disease-associated genes as those in the general population, but they may also be blessed with protective genes that help them live so long, researchers report.

The team of U.S. scientists noted that supercentenarians, as they are called, are extremely rare, with only one per 5 million people in developed nations. There is growing evidence that genetics play a major role in living to such an old age.

In what they describe as a first-of-a-kind study, the researchers analyzed the whole genome sequences of a man and a woman who lived past the age of 114 and found that they had as many disease-associated genes as other people.

For example, the man had 37 genetic mutations associated with increased risk for colon cancer.

"In fact, he had presented with an obstructing colon cancer earlier in his life that had not metastasized and was cured with surgery. He was in phenomenal cognitive and physical shape near the time of his death," study senior author Dr. Thomas Perls, director of the New England Centenarian Study, said in a Boston University Medical Center news release.

The woman had numerous genetic variations associated with age-related disease, such as heart disease, cancer and Alzheimer's disease. She did develop congestive heart failure and mild cognitive impairment, but these conditions didn't become evident until she was more than 108 years old.

"The presence of these disease-associated variants is consistent with our and other researchers' findings that centenarians carry as many disease-associated genes as the general population," Perls said. "The difference may be that the centenarians likely have longevity-associated variants that cancel out the disease genes. That effect may extend to the point that the diseases don't occur -- or, if they do, are much less pathogenic or markedly delayed towards the end of life, in these individuals who are practically living to the limit of the human lifespan."

The study was published Jan. 3 in the journal Frontiers in Genetics, and researchers will be able to access the information at the U.S. National Institutes of Health data repository.

More information

The American Academy of Family Physicians discusses good health habits at age 60 and older.

-- Robert Preidt

SOURCE: Boston University Medical Center, news release, Jan. 3, 2012

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Like Babies, Dogs Pick Up on Peoples Intent
2. Music May Help Ease Pain for Anxious People
3. New clues as to why some older people may be losing their memory
4. Poor People May Be Quicker to Be Kind
5. Holiday Travel Tips for People With Diabetes
6. Driving Isnt An Issue for Most People With Diabetes
7. Are Too Many Older People Screened for Cancer?
8. Tele-assistance for sports people
9. People with DFNA2 hearing loss show increased touch sensitivity
10. Behavior of people faced with health-care choices is not influenced by framing effect, study finds
11. Swedish people are quick to adopt JoVE, a video journal for biomedical sciences
Post Your Comments:
Related Image:
Why Some People Live to 110
(Date:11/28/2015)... (PRWEB) , ... November 28, 2015 , ... Trying to ... has created the COUCH BUDDY. "I conceived of this design due to personal experience ... for couch users. It promotes relaxation and convenience, as well as increases support. It ...
(Date:11/27/2015)... ... ... According to an article published November 6th by The Telegraph, ... British Columbia suggested that laws requiring bicyclists to wear helmets may not actually decrease ... reason for the controversial conclusion is that, while helmets have certainly prevented a great ...
(Date:11/27/2015)... PA (PRWEB) , ... November 27, 2015 , ... ... how filthy the toilets were," said an inventor from Hillside, N.J. "Many people ... improved seat cover so that individuals will always be protected from germs." , ...
(Date:11/27/2015)... ... November 27, 2015 , ... ... through sharing, the 2016 Building Better Radiology Marketing Programs meeting will ... on Sunday, March 6, 2016, at Caesars Palace in Las Vegas with a ...
(Date:11/27/2015)... ... November 27, 2015 , ... CBD College is proud to announce ... (CAAHEP) awarded accreditation to its Diagnostic Medical Sonography program. CBD College is honored to ... of twelve colleges and universities in the state of California make the cut. CBD ...
Breaking Medicine News(10 mins):
(Date:11/29/2015)... Nov. 29, 2015  The GE Health Cloud 1 ... Society of North America (RSNA) meeting ... healthcare industry, the new cloud ecosystem and its applications will ... care pathways and multidisciplinary teams – both inside and outside ... and CEO of GE. "As the digital industrial leader, we ...
(Date:11/27/2015)... , Niederlande, November 27, 2015 ... fotodynamischer Bremachlorin-Therapie bei fortgeschrittenem Krebs.   --> ... Bremachlorin-Therapie bei fortgeschrittenem Krebs.   --> ... Bremachlorin-Therapie bei fortgeschrittenem Krebs.   Clinical ... --> Clinical Cancer Research vom ...
(Date:11/26/2015)... Un nuevo enfoque combina la ... cáncer avanzado.   --> Un nuevo ... Bremachlorin para el cáncer avanzado.   --> ... la terapia fotodinámica de Bremachlorin para el cáncer avanzado. ... --> Clinical Cancer Research . --> ...
Breaking Medicine Technology: