Navigation Links
Why Some People Live to 110
Date:1/9/2012

SUNDAY, Jan. 8 (HealthDay News) -- People who live 110 years or longer have as many disease-associated genes as those in the general population, but they may also be blessed with protective genes that help them live so long, researchers report.

The team of U.S. scientists noted that supercentenarians, as they are called, are extremely rare, with only one per 5 million people in developed nations. There is growing evidence that genetics play a major role in living to such an old age.

In what they describe as a first-of-a-kind study, the researchers analyzed the whole genome sequences of a man and a woman who lived past the age of 114 and found that they had as many disease-associated genes as other people.

For example, the man had 37 genetic mutations associated with increased risk for colon cancer.

"In fact, he had presented with an obstructing colon cancer earlier in his life that had not metastasized and was cured with surgery. He was in phenomenal cognitive and physical shape near the time of his death," study senior author Dr. Thomas Perls, director of the New England Centenarian Study, said in a Boston University Medical Center news release.

The woman had numerous genetic variations associated with age-related disease, such as heart disease, cancer and Alzheimer's disease. She did develop congestive heart failure and mild cognitive impairment, but these conditions didn't become evident until she was more than 108 years old.

"The presence of these disease-associated variants is consistent with our and other researchers' findings that centenarians carry as many disease-associated genes as the general population," Perls said. "The difference may be that the centenarians likely have longevity-associated variants that cancel out the disease genes. That effect may extend to the point that the diseases don't occur -- or, if they do, are much less pathogenic or markedly delayed towards the end of life, in
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Like Babies, Dogs Pick Up on Peoples Intent
2. Music May Help Ease Pain for Anxious People
3. New clues as to why some older people may be losing their memory
4. Poor People May Be Quicker to Be Kind
5. Holiday Travel Tips for People With Diabetes
6. Driving Isnt An Issue for Most People With Diabetes
7. Are Too Many Older People Screened for Cancer?
8. Tele-assistance for sports people
9. People with DFNA2 hearing loss show increased touch sensitivity
10. Behavior of people faced with health-care choices is not influenced by framing effect, study finds
11. Swedish people are quick to adopt JoVE, a video journal for biomedical sciences
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Why Some People Live to 110
(Date:10/22/2014)... October 22, 2014 On October 22, ... featuring skin diseases both fictional and real. The ... a nonprofit organization committed to advocacy and philanthropy in ... will take the opportunity to impart truth and clarity ... , There are many misconceptions about Morgellons Disease ...
(Date:10/22/2014)... The United States is now mandating that all ... Africa land at one of five airports equipped ... In a statement released Tuesday, Homeland Security ... air passengers from Guinea, Liberia and Sierra Leone ... -- New York City,s Kennedy International Airport, Washington ...
(Date:10/22/2014)... During the Western United States’ worst ... dangerously low, Southern Oregon’s water is proving resistant to ... lowest mountain snow pack on record in 2014, remain ... autumn.* That was the observation of journalist-hikers Art Bernstein ... Southern Oregon,” during an interview with water advocate Sharon ...
(Date:10/22/2014)... Viejo, CA (PRWEB) October 22, 2014 ... Jay Cormier, Sr. Vice President of Sales, will be ... the upcoming Meetings Technology Expo on October 28, at ... also be hosting a booth as well as a ... how Lintelus Meeting can create a more engaging event ...
(Date:10/22/2014)... TUESDAY, Oct. 21, 2014 (HealthDay News) -- Two sisters ... and heart damage. Ilina and Medha Krishen use ... for sounds of trouble in breathing patterns or heartbeats. ... School in Michigan, wanted to find a way to ... air pollutants. Using an electronic stethoscope, Ilina recorded one ...
Breaking Medicine News(10 mins):Health News:CBS’ Criminal Minds takes aim at skin disease with Morgellons in the Mix 2Health News:CBS’ Criminal Minds takes aim at skin disease with Morgellons in the Mix 3Health News:Passengers From Ebola-Affected Countries Must Land at Designated U.S. Airports 2Health News:Passengers From Ebola-Affected Countries Must Land at Designated U.S. Airports 3Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 2Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 3Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 4Health News:Jay Cormier, Sr. Vice President of Sales for Lintelus, Speaks about Event Technology Integration at Meetings Technology Expo in NYC 2Health News:Teen Sisters Develop Ways to Measure Lung, Heart Damage 2
... preserving Blue Cross,s nonprofit mission gives Michigan ... LANSING, Mich., Jan. 30 Creation of ... people rejected by,commercial insurers and HMOs because of ... the Michigan Senate Health Policy Committee,today. The Senate ...
... Special,Committee on Aging, in conjunction with the Medical ... for Aging Services Technologies (CAST),today hosted a briefing ... in services for America,s seniors., At the ... current,technology consumers discussed technology,s potential to facilitate,independence and ...
... help cells regulate which proteins they make might one ... to live longer than others, new research suggests., Researchers ... and adjacent nontumor cells from liver-cancer patients, most of ... found that patients with poor disease-free survival had low ...
... Number 1 Killer of Women, HARRISBURG, Pa., Jan. ... on Friday, the Pennsylvania Commission for Women,is encouraging the ... Red Day., Red is the signature color of ... aims to raise awareness about heart disease, the,number one ...
... a report, the Mental Health Advisory Team IV, that studied soldier mental health ... look at that study, exploring the three most critical elements of the 100-page ... The intensity of combat and other stressors of those serving down range ... Battlefield ethics , ...
... Dreams of Terminally Ill,Stage Performer, NEW YORK, Jan. 30 ... eye - whether he was performing on Broadway,acting and dancing ... two years ago, cancer robbed him of his,mobility, forcing him ... to get outside again, The SCOOTER Store has donated a ...
Cached Medicine News:Health News:Blue Cross Blue Shield of Michigan Says Guaranteed Access Provisions of Insurance Reform Bills Protect Michigan Consumers Twice-Over 2Health News:Blue Cross Blue Shield of Michigan Says Guaranteed Access Provisions of Insurance Reform Bills Protect Michigan Consumers Twice-Over 3Health News:Capitol Hill Briefing Features Technologies That Could Transform the Lives of Seniors 2Health News:Capitol Hill Briefing Features Technologies That Could Transform the Lives of Seniors 3Health News:Molecules may help predict survival in liver cancer 2Health News:Former Actor has Mobility Restored With Power Wheelchair Gift From The Scooter Store 2
(Date:10/22/2014)... AUSTIN, Texas , Oct. 22, 2014 ... announced they have entered into a license and ... to target cancers. PhosImmune possesses technology ... the surfaces of tumor cells in association with ... from proteins that play a role in malignancy, ...
(Date:10/22/2014)... 2014  Recently published clinical studies of Stretta for ... database of evidence. This data has led to significantly ... therapy for sufferers of refractory GERD. ... Stretta therapy as a safe and effective GERD treatment ... available to nearly 50 million Americans. The new clinical ...
(Date:10/20/2014)... 2014  PneumRx, Inc. ( www.pneumrx.com ), a leader ... of enrollment in their RENEW Study, nearly 3 months ... FDA-approved IDE pivotal trial for the PneumRx RePneu Coil ... was anticipated that the study, which began enrolling subjects ... the end of 2014 to enroll 315 patients.  Instead, ...
Breaking Medicine Technology:Biotech Companies To Co-Discover And Co-Develop Antibodies Targeting Novel Phosphopeptide Tumor Targets 2Recent Clinical Study Data Confirms Efficacy of Stretta Therapy - Spurs Additional Insurance Coverage and Financing Round 2PneumRx Completes RENEW Pivotal Trial Enrollment 2PneumRx Completes RENEW Pivotal Trial Enrollment 3
... Perrigo Company (Nasdaq: PRGO;TASE) today announced that ... approvals necessary to complete the acquisition of Paddock ... of generic Rx pharmaceuticals and OTC specialty products. ... C. Papa stated, "We are looking forward to ...
... Corporation ("Unilife" or the "Company") (NASDAQ: UNIS ... completed the validation phase of the Unifill® ready-to-fill (prefilled) ... in the industrialization process for the Unifill syringe. ... completion of all validation tests associated with the Unifill ...
Cached Medicine Technology:Perrigo Provides Update on Acquisition of Paddock Labs 2Perrigo Provides Update on Acquisition of Paddock Labs 3Unilife Successfully Completes Industrialization of Unifill Syringe 2Unilife Successfully Completes Industrialization of Unifill Syringe 3Unilife Successfully Completes Industrialization of Unifill Syringe 4
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: