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Whole-parasite malaria vaccine shows promise in University of Maryland School of Medicine clinical trial
Date:9/9/2011

istering the vaccine might include novel microneedle injection devices. If these studies continue to show promise, the next step would be to test the whole parasite vaccine's ability to prevent malaria in people naturally exposed to malaria.

"We would love to test this vaccine in Mali," says Dr. Plowe, who leads the Malaria Section at the University of Maryland School of Medicine and has led several malaria vaccine trials in Mali, West Africa. There, his team found that highly variant malaria parasites are difficult to prevent with single-strain, single-protein vaccines. "That will be the real test does this vaccine have enough immunological firepower to protect against all the different strains circulating in the field, not just the strain the vaccine is based upon? If the whole parasite doesn't work, I don't know what will this is the best chance we've got."


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Contact: Karen Robinson
karobinson@som.umaryland.edu
410-706-7590
University of Maryland Medical Center
Source:Eurekalert

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