Navigation Links
Whole-parasite malaria vaccine shows promise in University of Maryland School of Medicine clinical trial
Date:9/9/2011

e against just certain strains. Whole parasite vaccines have seemed unattainable because of the many challenges of large-scale production and preservation of whole parasites, which can only be produced by infecting mosquitoes with malaria-infected blood. Using mosquitoes raised in aseptic conditions, Sanaria Inc. developed a unique large-scale production and cryopreservation process, allowing the parasite to be frozen, shipped to remote locations and safely thawed.

Dr. Lyke collaborated with fellow University of Maryland School of Medicine scientists including Matthew B. Laurens, M.D., M.P.H., assistant professor of pediatrics and medicine, and Christopher Plowe, M.D., professor of medicine, epidemiology and public health and microbiology and immunology and leader of the Malaria Group at the School of Medicine. Dr. Plowe is also a Doris Duke Distinguished Clinical Scientist and an investigator at the Howard Hughes Medical Institute. Robert Edelman, M.D., clinical professor of medicine and pediatrics at the School of Medicine, also contributed to the paper. The group co-authored the study with colleagues from the Howard Hughes Medical Institute, the Walter Reed Army Institute of Research, the PATH Malaria Vaccine Initiative and the biotechnology firm Protein Potential LLC.

The parasite used in the vaccine is a sporozoite, an early life-cycle stage of the parasite Plasmodium falciparum, the most dangerous type of malaria parasite. The sporozoite is carried in the salivary glands of a mosquito, where it infects a human through the mosquito's bite. The sporozoites used in the vaccine were rendered harmless when Sanaria's manufacturing team administered radiation to the mosquitoes carrying the parasites. The radiation leaves the sporozoites incapable of reproducing and incapable of causing malaria once the human is bitten. Instead, the sporozoite is intended to stimulate the body's immune response, creating immunity to malaria.

Previous studie
'/>"/>

Contact: Karen Robinson
karobinson@som.umaryland.edu
410-706-7590
University of Maryland Medical Center
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. MARA Fights Malaria With WaveMaker and Amazon Web Services
2. One-third of antimalarial medicines sampled in 3 African nations found to be substandard
3. Private Sector, President's Malaria Initiative Join Forces to Strengthen Angolas Capacity to Control Mosquitoes
4. UCR researcher identifies mechanism malaria parasite uses to spread in red blood cells
5. Tony Blair Visits Pioneering Interfaith Malaria Initiative in Nigeria
6. Malaria research must be based in Africa
7. Invisible Children's Bobby Bailey Premiers a New Documentary on Malaria
8. High School Student's College Prerequisite: Save Five Thousand Lives in Africa. Teen Supports Nothing But Nets in Malaria Fight
9. SC Johnson and Bill & Melinda Gates Foundation Unite to Combat Malaria
10. Grassroots Campaign Drives toward Ending Malaria Deaths by 2015
11. Mosquito Squad Partners with Malaria No More
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/29/2015)... May 29, 2015 Intermountain ... partnered with Stratus Video Interpreting ... facilitate better communication and timely care for ... hearing loss. Stratus’ video remote interpreting (VRI) ... enabling staff to quickly access qualified medical ...
(Date:5/29/2015)... 29, 2015 Mediaplanet has joined forces ... readers on the importance of proper sun protection. The ... Today, with a circulation of approximately 250,000 copies and ... is distributed nationally, through a vast social media strategy, ... partner outlets. To explore the digital version of the ...
(Date:5/29/2015)... Chicago, Ill (PRWEB) May 29, 2015 ... Care , a dozen medical pioneers recognized by a ... changed the course of cancer treatment. Honorees will be ... of Cancer Care™ Award Ceremony, held 8:30-11:00 p.m. CDT ... , The 2015 honorees are being recognized for groundbreaking ...
(Date:5/29/2015)... TX (PRWEB) May 29, 2015 ... 2015” provides comprehensive information on the therapeutic development ... types of muscles in the body, leading to ... R&D pipelines by identifying new targets and MOAs ... on H1 2015 pipeline review of Axillary Hyperhidrosis ...
(Date:5/29/2015)... Dr. Rodger Murphree, author of ... is now offering free weekly call in teleconferences ... ways to reduce symptoms associated with fibromyalgia including ... brain fog. , To find out more ... call in teleconferences simply go to http://www.endfibronow.com ...
Breaking Medicine News(10 mins):Health News:Stratus Video Interpreting Partners With Intermountain Healthcare to Provide On-Demand Interpretation Services for Patients With Limited English Proficiency (LEP) 2Health News:Stratus Video Interpreting Partners With Intermountain Healthcare to Provide On-Demand Interpretation Services for Patients With Limited English Proficiency (LEP) 3Health News:Stratus Video Interpreting Partners With Intermountain Healthcare to Provide On-Demand Interpretation Services for Patients With Limited English Proficiency (LEP) 4Health News:OncLive's 2015 Giants of Cancer Care™ Awards Announced Today 2Health News:OncLive's 2015 Giants of Cancer Care™ Awards Announced Today 3Health News:OncLive's 2015 Giants of Cancer Care™ Awards Announced Today 4Health News:Muscle Spasm Therapeutic Development Pipeline Review H1 2015 Market Research Report Available at RnRMarketResearch.com 2Health News:Muscle Spasm Therapeutic Development Pipeline Review H1 2015 Market Research Report Available at RnRMarketResearch.com 3Health News:Muscle Spasm Therapeutic Development Pipeline Review H1 2015 Market Research Report Available at RnRMarketResearch.com 4
... PA, January 3, 2011 Postoperative adhesions are a ... used in the hopes of preventing these adhesions by ... in the December 2010 issue of the Journal ... Association of Pediatric Ophthalmology and Strabismus, a team of ...
... entered into a collaborative agreement with Veridex LLC to ... tumor cell (CTC) technologies. The overall goal of the ... capturing and characterizing CTCs, solid tumor cells found at ... a key to noninvasive characterization of cancer and potentially ...
... , SUNDAY, Jan. 2 (HealthDay News) -- Snowblowers ... the white stuff, but while these machines may leave your ... bandage -- or worse, experts warn. A hand surgeon ... accidents can severely injure hands and even require finger amputations ...
... , THURSDAY, Dec. 30 (HealthDay News) -- Certain ... a new study finds. Because of increasing urbanization, ... more than ever before. For example, foxes, raccoons and ... mice, rats, birds and other prey. For this ...
... , , , , , , ... , , AUDIO: ... , Click here for more information. , ... , , , , ...
... THURSDAY, Dec. 29 (HealthDay News) -- Following mothers, advice may ... crisis. Fears of the H1N1 flu virus reached a ... widespread outbreak caused by short supplies of the needed vaccine. ... that,s because more people than ever before regularly washed their ...
Cached Medicine News:Health News:Use of amniotic membrane may cause complications in strabismus surgery 2Health News:Mass. General enters collaboration to develop new approach to capturing circulating tumor cells 2Health News:Risk for alcoholism linked to risk for obesity 2Health News:Risk for alcoholism linked to risk for obesity 3Health News:Risk for alcoholism linked to risk for obesity 4Health News:Hand-Washing May Have Kept Flu at Bay 2Health News:Hand-Washing May Have Kept Flu at Bay 3
(Date:5/29/2015)... MEMPHIS, Tenn. , May 29, 2015  Dr. ... his practice to resolve vaginal health issues often caused by ... painless and requires no anesthesia, received FDA clearance in 2014. ... Tennessee to offer the special fractional CO ... well as breast cancer survivors. In 2010 ...
(Date:5/29/2015)... LifeNet Health plans to enlarge its workforce ... more than 160 people. The organization,s growth ... innovative bio-implants, which are being made more widely available ... It also is a reflection of the region,s growing ... and success of LifeNet Health is a great example ...
(Date:5/29/2015)... and MENLO PARK, Calif. ... DelMar Pharmaceuticals, Inc. (OTCQX: DMPI) ("DelMar" and ... and commercializing proven cancer therapies in new orphan ... American Association of Cancer Research (AACR) Advances ... potential for its lead product candidate VAL-083 ...
Breaking Medicine Technology:The Newest FDA-Cleared Breakthrough In Women's Health Treatments 2LifeNet Health to add more than 160 jobs in 2015 2DelMar Pharmaceuticals Presents Additional Data on the Potential of VAL-083 in the Treatment of Temozolomide-Resistant Glioblastoma Multiforme 2DelMar Pharmaceuticals Presents Additional Data on the Potential of VAL-083 in the Treatment of Temozolomide-Resistant Glioblastoma Multiforme 3DelMar Pharmaceuticals Presents Additional Data on the Potential of VAL-083 in the Treatment of Temozolomide-Resistant Glioblastoma Multiforme 4DelMar Pharmaceuticals Presents Additional Data on the Potential of VAL-083 in the Treatment of Temozolomide-Resistant Glioblastoma Multiforme 5
... AAHC Calls for National Entity to Address Workforce ... center CEOs told congressional staff and representatives of ... that pending health reform legislation does not yet ... to implement successful health system reform. "Pending ...
... AMN Healthcare Services, Inc. (NYSE: AHS ), the ... its quarterly conference call to discuss third quarter results on ... company also expects to issue an earnings news release on ... approximately 4:00 p.m. Eastern Time. , A live webcast of ...
Cached Medicine Technology:Health Reform Bills Still Lack Strategic Focus on Health Workforce 2AMN Healthcare Services to Host 2009 Third Quarter Earnings Conference Call on Thursday, October 29, 2009 2
2.0mm Rounded Tip, 12mm From Tip to Bend Gently Curved, 15mm Shaft; In Titanium...
Double ended with 0.5mm x 10mm and 1.0mm x 15mm blades; both blades gently curved; round serrated handle, In Titanium....
0.6mm Tip x10mm Shaft, Straight Shaft, 90 Degree Hook at Tip; overall length 120mm; in Titianium....
... The SURPASS Perfusion Catheter is ... the stenotic portion of a ... stenosis for the purpose of ... Perfusion Catheters are also designed ...
Medicine Products: