Navigation Links
Whole-genome scan helps select best treatment for childhood cancer
Date:9/14/2012

A whole-genome scan to identify large-scale chromosomal damage can help doctors choose the best treatment option for children with neuroblastoma, one of the most common types of childhood cancer, finds an international collaboration jointly led by The Institute of Cancer Research, London.

The researchers called for all children diagnosed with neuroblastoma worldwide to have a whole-genome scan as a standard part of their treatment.

Neuroblastoma, a cancer of the developing nervous system, is sometimes very treatable but other forms are highly aggressive, making the disease overall one of the leading causes of death from childhood cancer. As intense treatments can carry life-long side-effects, identifying the form is crucial in giving an accurate prognosis and deciding the most appropriate care.

Scientists examined the medical records of 8,800 neuroblastoma patients from around the world and found that several large-scale genetic faults were strongly linked to survival rates, and that a whole-genome scan would therefore be more effective at predicting prognosis than tests for individual genetic factors. The study is published in the British Journal of Cancer today.

Senior author Professor Andy Pearson, Cancer Research UK professor of paediatric oncology at The Institute of Cancer Research and a paediatric consultant at The Royal Marsden NHS Foundation Trust, said: "Our study has found that every single patient diagnosed with neuroblastoma should have a whole genome assessment. The technology required to carry out these scans has become much more widely available and cheaper over recent years, and we believe most diagnostic labs in developed countries worldwide should have this capacity. These gene tests would help doctors provide a more accurate prognosis and decide the best treatment for their patients, which could potentially save more lives and spare other children the risk of serious side-effects."

The
'/>"/>

Contact: ICR Science Communication Manager Jane Bunce
jane.bunce@icr.ac.uk
44-207-153-5106
Institute of Cancer Research
Source:Eurekalert

Page: 1 2

Related medicine news :

1. New software helps reveal patterns in space and time
2. LifeSkills training helps teens manage anger, lower blood pressure
3. Theres an app for that: Apple iPod Touch helps adults with autism function in the workplace
4. New technique helps determine degree of muscle wasting in critically ill patients
5. Intervention helps children with sickle cell disease complete MRI tests without sedation
6. Study helps pancreatic cancer patients make hard choices
7. Radiation after lumpectomy helps prevent need for mastectomy in early stage breast cancer
8. Mechanical Device Helps Kids Waiting for Heart Transplant
9. More Evidence That Exercise Helps Fight Diabetes
10. Blue light helps tired workers and motorists regulate their internal clocks
11. IL-10 from donor skin cells helps the body incorporate skin grafts
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2015)... ... August 01, 2015 , ... On March 19, 2015 Phil Valentine – the Executive Director ... Appalachian Trail by stepping off Springer Mountain and heading north. Since that day, ... Phil reached Connecticut and was greeted by friends and family. He visited CCAR and ...
(Date:7/31/2015)... ... 2015 , ... When the weather turned hot and warm-season turfgrasses, such as ... called Leisure Time(TM) zoysia . It's nicknamed LTZ(TM) for short. Incidentally, both names ... new type of sod, Super-Sod is giving away red Adirondack chairs with the Leisure ...
(Date:7/31/2015)... ... 2015 , ... Ticket Down is a reliable source for authentic tickets for ... Park. The festival will end on Sunday, August 2nd. , Music ... Lollapalooza. This unique and unbelievably popular festival attracts the best in entertainment from ...
(Date:7/31/2015)... Alexandria, VA (PRWEB) , ... July 31, 2015 ... ... Foundation) introduced its new store run by GoodThreads. The store can be accessed ... products and designs, many of which are customizable. The best part: whenever a ...
(Date:7/31/2015)... ... 2015 , ... There’s no better way to enjoy the summer weather than ... the next meal, making July the most appropriate to be National Hot Dog Month. ... , Make the next cookout different than the ones in the past. Celebrate National ...
Breaking Medicine News(10 mins):Health News:Connecticut Executive Hikes Appalachian Trail to Raise Awareness About Recovery. 2Health News:Super-Sod Introduces Leisure Time(TM) Zoysia Grass with an Adirondack Chair Promotion 2Health News:Cheap 2015 Lollapalooza Tickets: Ticket Down Slashes Ticket Prices on Lollapalooza Tickets at Grant Park in Chicago for Saturday, August 1st and Sunday, August 2nd 2Health News:Mesothelioma Organization Launches New Store 2Health News:Mesothelioma Organization Launches New Store 3Health News:King Kullen Honors National Hot Dog and Blueberry Month 2Health News:King Kullen Honors National Hot Dog and Blueberry Month 3
... leading hospital here, has successfully completed formalities for an ... patients from abroad. ,"A team of ... Standards International (ACHSI), under the leadership of Dr. John ... KIMS has become the first hospital in India to ...
... abnormal vaginal bleeding and pelvic pain caused by growth ... fear of losing// fertility as the available treatments do not ... at Thomas Jefferson University Hospital in Philadelphia published in the ... of a 35-year-old women whose numerous fibroids formed a large ...
... in their mother’s womb, show significant reduction in mental ... also have a// higher risk for behavior problems. This ... Academy of Pediatrics. , Chlorpyrifos, which was ... applied to agricultural crops in the U.S. and abroad, ...
... credited with eradicating diseases such as diphtheria, polio and ... a bad rap.// ,Some people believe that ... Some say they are no longer needed because most ... think vaccinations are just for children. ,According ...
... hoping to exploit the passion for cricket among South Asians ... not to delay calling// emergency help when experiencing chest pain. ... a 40-50 per cent higher death rate from heart disease ... be reluctant to seek emergency help for various reasons: doubt, ...
... can be inserted inside the lungs with the help of ... treat asthma, researchers conducting its// trial said., ,Asthma is ... airways constrict making it hard to breathe. At its worst, ... cured, it can be managed with proper treatment. People with ...
Cached Medicine News:Health News:Does Treatment of Fibroids Guarantee Fertility ? 2Health News:Chlorpyrifos Affects Mental Development of Foetus 2Health News:Vaccines — Good for Adults to 2Health News:British Heart Experts Use Cricket To Target South Asians 2
(Date:7/31/2015)... CHICAGO , July 31, 2015 ... Composition Analyzers Market by Product (Bioimpedance Analyzers (BIA), Dual-Energy ... and Hydrostatic Weighing) - Global Analysis & Forecast to ... Market was pegged at $911.1 Million 2014 and is ... at a CAGR of 9.4% from 2014 to 2019. ...
(Date:7/30/2015)... 2015  ResMed (NYSE: RMD ) ... agreement to acquire Curative Medical, a privately-held ... breathing medical devices and accessories. ... leadership in sleep and respiratory medicine, will ... suffering from sleep-disordered breathing and ...
(Date:7/30/2015)... IRVINE, Calif. , July 30, 2015 /PRNewswire/ ... Novartis /Alcon executives have recently contacted the Company ... will begin as early as Monday, August 3, ... been quoted as saying that the coming electronic ... billions of dollars over the next several years.  ...
Breaking Medicine Technology:Body Composition Analyzers Market Worth $1,425.7 Million by 2019 2Body Composition Analyzers Market Worth $1,425.7 Million by 2019 3Body Composition Analyzers Market Worth $1,425.7 Million by 2019 4ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 2ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 3
... test available nationally, LYNDHURST, N.J., Aug. ... chromosome abnormalities associated with 85,developmental disorders affecting ... diagnostic testing company, affording testing and,reimbursement by ... Diagnostics,Incorporated (NYSE: DGX ), the nation,s ...
... to Inform Patients with Recurrent Ovarian Cancer ... about the OVATURE Clinical Research Study, NEW CANAAN, ... facilitate recruitment of patients to OVATURE (OVArian,TUmor REsponse), a Phase ... goal of http://www.OVATUREtrial.com is to inform,ovarian cancer patients ...
Cached Medicine Technology:Quest Diagnostics Introduces ClariSure(TM) Test for Identifying Chromosome Abnormalities Associated With 85 Developmental Disorders in Children 2Quest Diagnostics Introduces ClariSure(TM) Test for Identifying Chromosome Abnormalities Associated With 85 Developmental Disorders in Children 3Quest Diagnostics Introduces ClariSure(TM) Test for Identifying Chromosome Abnormalities Associated With 85 Developmental Disorders in Children 4A Worldwide Phase III Clinical Trial Seeks U.S. Patients to Explore Investigational Drug Phenoxodiol 2A Worldwide Phase III Clinical Trial Seeks U.S. Patients to Explore Investigational Drug Phenoxodiol 3A Worldwide Phase III Clinical Trial Seeks U.S. Patients to Explore Investigational Drug Phenoxodiol 4A Worldwide Phase III Clinical Trial Seeks U.S. Patients to Explore Investigational Drug Phenoxodiol 5A Worldwide Phase III Clinical Trial Seeks U.S. Patients to Explore Investigational Drug Phenoxodiol 6
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: