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Whole fresh blood for transfusions may have a longer shelf life than now assumed
Date:2/23/2011

ladelphia. They found that thromboelastography (TEG) and platelet aggregation levels, which measure the efficiency of blood coagulation, remain normal at least 11 days under standard refrigerated conditions.

If these results hold up under follow-up studies in human subjects, a change in current practice could increase the availability and usefulness of whole blood, especially in military or disaster relief situations, and in remote locations. "Trauma patients could potentially benefit, as well as others needing a large volume of blood replacement, such as patients undergoing liver transplant or children who need craniofacial reconstruction," said Jobes.

Furthermore, Jobes added, more efficient use of donated whole blood, besides reducing wastage, could lower the number of donors needed, and thus increase safety by reducing the risks of inadvertently transmitting blood borne viruses.

In all, said Jobes, "Our results strongly suggest that clinical trials should proceed to test the value of whole blood beyond a 48-hour period."


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Contact: Joey McCool Ryan
McCool@email.chop.edu
267-426-6070
Children's Hospital of Philadelphia
Source:Eurekalert

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