Navigation Links
Which is more accurate, serology test or C14-urea breath test?

Serology and C14-UBT are the most commonly used non-invasive tests of H. pylori infection. The diagnostic characteristics of the tests depend also on the prevalence of H. pylori infection in the population tested. The diagnostic characteristics of the tests depend also on the prevalence of H. pylori infection in the population tested. Higher prevalences would imply higher sensitivity and lower specificity. There are reports suggesting that there is an association between the level of H. pylori IgG antibodies and the severity of inflammation of the gastric mucosa and also between antibody level and a current peptic ulcer. If so, the level, not only positively or not, of H. pylori IgG antibody tests might be of clinical importance.

A research article to be published on August 28, 2008 in the World Journal of Gastroenterology addresses this question. The research team was led by Dr. Rolv-Ole Lindsetmo and his colleagues in the University of Troms in Norway.

They showed by comparing H. pylori IgG antibodies from two peptic ulcer populations that coming from a background population with a high H. pylori prevalence, that the level of IgG antibodies could not be used to predict active peptic ulcer disease and did not show any association with gastric mucosal morphology.

Uncritical use of H. pylori serology will represent a considerable overestimation of H. pylori prevalence in the population tested. A negative H. pylori serology test result is on the other hand very reliable to exclude H. pylori infection and thereby useful in screening purposes.

Dr. Lindsetmo believes that H. pylori serology should be limited to screening and research purposes and that H. pylori serology has limited value in daily clinical practice.


Contact: Lai-Fu Li
World Journal of Gastroenterology

Page: 1

Related medicine news :

1. Which Candidate Has the Perfect Smile, Senator Obama or McCain? TransMedia Group to Publicize Special Election So Florida Voters Can Decide
2. Which is accurate, CT or MRI?
3. New Method Proposed for Determining Which Patients Should Get Treatment for Colorectal Cancer
4. New method proposed for determining which patients should get treatment for colorectal cancer
5. Biomarker Spots Which Lesions Likely to Progress to Prostate Cancer
6. Hats Off to the Red Hat Society, Which Turns 10 Today
7. Which came first, social dominance or big brains? Wasps may tell
8. Researchers describe mechanisms by which capon gene causes heart rhythm disturbances
9. Bradmer announces Phase II results published in newly diagnosed glioblastoma which demonstrate improved survival and support upcoming Phase III study
10. Study identifies which men are likely to have persistent prostate cancer
11. OxySure(R) Systems, Inc. Named to 2008 Worlds Best Technologies (WBT) List For its Unique, Safe and Easy to Use Portable Emergency Oxygen Generator, Which Provides Medical Oxygen Without the Need for Compressed Tanks
Post Your Comments:
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... On November ... United States District Court of Connecticut on behalf of a home health care worker ... all current or former home health care workers employed by Humana, Inc., Humana at ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... across the country to celebrate their sobriety and show through pictures what a ... and after” photos this Thanksgiving with the hashtag #FacesOfGratitude on their Facebook, Twitter, ...
(Date:11/25/2015)... Florida (PRWEB) , ... November 25, 2015 , ... ... testing for physicians and athletic programs, launches new Wimbledon Athletics Facebook ... of testing young athletes for unsuspected cardiac abnormalities. About 2,000 people under the ...
(Date:11/25/2015)... ... November 25, 2015 , ... Smiles by Stevens is pleased ... moderate facial wrinkling. While many patients are aware of the benefits of Botox® in ... delivers to those suffering with discomfort, soreness, and pain as a result of Jaw ...
(Date:11/25/2015)... ... November 25, 2015 , ... Brillianteen, McGaw YMCA’s ... learning in its 65th Anniversary Brillianteen Revue, scheduled for March 4-6, 2016. Auditions ... 65 years, Brillianteen has been a treasured tradition for numerous families in the ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , Nederland, November 26, 2015 ... Een nieuwe aanpak combineert immunotherapie met ... kanker. ) ...      (Photo: ) ... Leids Universitair Medisch Centrum (LUMC) ...
(Date:11/26/2015)... 26, 2015 3D bioprinting market ... to a new report by Grand View Research Inc. Rising ... which demands kidney transplantation is expected to boost the market ... for organ transplantation. --> 3D bioprinting market ... to a new report by Grand View Research Inc. Rising ...
(Date:11/26/2015)... , November 26, 2015 ... the addition of the  "2016 Future ... Global Cell Surface Testing Market: Supplier ... to their offering.  --> ... of the  "2016 Future Horizons and ...
Breaking Medicine Technology: