Navigation Links
Where You Put on Pounds May Influence Clot Risk

Big hips in women, wide waists in men spell trouble, study finds

MONDAY, Oct. 26 (HealthDay News) -- The location of excess body fat appears to affect the risk of dangerous blood clots in veins, although that location differs in men and women, a new Danish study indicates.

The 10-year study found that bigger hips are associated with an increased risk of venous thromboembolism (VTE) in women but not men, while a wider waistline was associated with increased risk in men, according to a report published online Oct. 26 in the journal Circulation.

Obesity in general is an established risk factor for VTE, which occurs when a blood clot blocks a vein. When VTE happens in a leg, it is known as deep vein thrombosis. In a lung, it is a pulmonary embolism. A particularly deadly form of VTE, thromboembolism, occurs when a clot travels from a leg to a lung.

Researchers at Aarhus University Hospital followed more than 57,000 Danish men and women, aged 50 to 64 when the study started, assessing the relationships between body mass, fat distribution and VTE. The initial analysis showed that waist circumference was associated with VTE risk in both men and women.

"When hip circumference was adjusted for waist circumference, the association between hip circumference and VTE was eliminated for men but was still significant for women," the report said. "In contrast, when waist circumference was adjusted for hip circumference, the association between waist circumference and VTE was eliminated for women but was still significant for men."

"Further studies are needed to explain the associations," they wrote.

The Danish study results echoes those of an American study reported earlier this year, said Lyn Steffen, an associate professor of epidemiology at the University of Minnesota School of Public Health, and a leader of that study.

The Minnesota group followed more than 20,000 people for more than 12 years and found an association between VTE risk and metabolic syndrome, a constellation of risk factors including obesity, high blood pressure, insulin resistance and high blood cholesterol. A heightened risk of VTE was attributed to obesity.

"The message here is that obesity is a risk factor for venous thrombosis," Steffen said. "The effect of obesity in women might be the same as in men, but just is not measured in waist circumference."

It's possible that obesity increases the likelihood of developing blood clots, and it also might have a negative effect on the endothelium, the delicate lining of blood vessels, Steffen said.

"There is information that obesity contributes to inflammation, and it is associated with the metabolic syndrome, which predisposes to stroke," said Dr. Amytis Towfighi, an assistant professor of clinical neurology at the University of Southern California. "There may be similar effects in thrombotic disease, as well as mechanisms that are not well understood at this point."

More information

Learn more about venous thrombosis from the U.S. National Heart, Lung, and Blood Institute.

SOURCES: Lyn Steffen, Ph.D, associate professor, epidemiology, University of Minnesota School of Public Health, Minneapolis; Amytis Towfighi, M.D., assistant professor, clinical neurology, University of Southern California, Los Angeles; Oct. 26, 2009, Circulation, online

Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Skin cells may provide early warning for cancer risk elsewhere in body
2. How should mental, neurological and substance use disorders be treated where resources are scarce?
3. iJETs Survive/Thrive Webinar Series Continues With Pandemic Influenza: Where Do We Stand?
4. Wheres the science? The sorry state of psychotherapy
5. Where surgery was the standard, casting may be the future
6. Outbursts: Where did Their IQ points Go and What were They Thinking?
7. Where is President Obamas Health Care Plan?
8. Teen Birth Rates Higher in States Where Religion Is Widespread
9. Does the distance a patient has to travel affect where they choose to get their care?
10. Medical Arts Radiology Chooses Optimum Lightpath to Speed Anytime, Anywhere Access to Patient Data and Communications
11. NYCs Only Walk-in Botox Clinic, SmoothMED - Where Boytox Hits Men Right in the Brow!
Post Your Comments:
(Date:12/1/2015)... ... December 01, 2015 , ... According to an article published on ... claim against the U.S. Department of Health and Human Services, claiming that any states ... are breaking the clause in the law prohibiting the denial of coverage for pre-existing ...
(Date:12/1/2015)... , ... December 01, 2015 , ... ... there are professionals who believe that with innovative technologies and under the right ... patient to get the benefit of a dual-approach to his or her therapeutic ...
(Date:12/1/2015)... ... December 01, 2015 , ... It’s official: Tattoo taboo ... — a number even greater among Millennials (a whopping one in three aged 18 ... more people who are dissatisfied with their ink. In fact, RealSelf , the ...
(Date:12/1/2015)... ... December 01, 2015 , ... For the ... is why Hollister Incorporated has launched the VaPro Plus Pocket™ touch free hydrophilic ... the VaPro touch free catheter portfolio,” said Michael Gresavage, Vice President North America. ...
(Date:12/1/2015)... ... December 01, 2015 , ... Lutronic, a leading innovator of aesthetic ... addition to the devices for sale in the United States. Clarity is a ... 1064 nm Nd:YAG lasers, into a single platform that is easy to own and ...
Breaking Medicine News(10 mins):
(Date:12/2/2015)... 2015 TB Alliance and its partners ... medicines in the correct doses. The improved treatments ... set by the World Health Organization (WHO) in ... administer and affordable. The availability of these products ... by UNITAID. ...
(Date:12/1/2015)... and VANCOUVER , Dec. 1, 2015 ... OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI ) announced today ... on the pre-planned interim futility analysis of the intent-to-treat ... safety issues were identified by the DMC. Both the ... final results are expected in the second half of ...
(Date:12/1/2015)... 01, 2015 ... the "Spinal Muscular Atrophy Market - ... 2015 - 2023" report to their ... announced the addition of the "Spinal ... Growth, Trends, and Forecast 2015 - 2023" ...
Breaking Medicine Technology: