Navigation Links
When poor communication pokes you in the eye
Date:4/7/2008

in the sequence of the gene building blocks can lead to proteins with limited or completely lost functions: and in this way, in the worst case, to serious diseases or development disorders. The Neuherberg eye researchers gave the name Gjf1 to the gene responsible for the alterations of the Aey12 mutant mice. It is a member of the Connexin family. The genes belonging to this group get the information for the construction of channel proteins, which build the cell to cell connections, Graw declares. Such channels are of great importance for the interchange between cells: also, among other things, between the fiber cells of the developing eye lens itself.

The scientists now speculate that through the newly discovered mutation, the structure of the Gjf1 channel protein is changed, and in this way the formation of the channel is hindered. But through this, the communication between the developing lens fibers would break down. Thus, it would be conceivable that signal molecules essential for the development of the lens are no longer exchanged, or only to a limited extent. In this scenario, faulty cell communication would be the cause of the development of the fibers stopping: and ultimately, of the cloudiness of the eye lens, which would otherwise be transparent. This very phenomenon is also observed in cataracts in humans, a common disease, which appears mostly in the elderly: in Germany alone more than half a million operations are carried out annually, in which the cloudy and opaque lens is replaced with an implant. Our results will surely also provide an insight into the origin of cataracts, Graw adds. Moreover, so far, there has not yet been any mutation in humans equivalent to Gjf1 gene of mice. But this will now change soon, for sure.


'/>"/>

Contact: Dr. Jochen Graw
graw@helmholtz-muenchen.de
49-893-187-2610
Helmholtz Zentrum Mnchen - German Research Center for Environmental Health
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Telecommunications Carriers Respond To Congress Declaration of April as National 9-1-1 Education Month
2. Leading Epilepsy Advocates Propose Strategies to Heighten Treatment Expectations and Close Patient and Physician Communication Gaps
3. Pennsylvania Patient Safety Authority Releases March Advisory Highlighting Communication Issues That Affect Patient Safety
4. AutismOnline.org Partners With Leading Health Communications Firm for Support
5. International Eye Foundation Announces Partnership with Newport Creative Communications
6. HeartWare Selects Allen & Caron for Investor Relations and Corporate Communications
7. Family communication impacts attitude about genetic counseling/testing for breast cancer
8. XCPT(TM) Patient Engagement and Communication Software and DentalXP.com, a Leading Provider of Online Dental Education and Content, Sign a Co-Marketing Agreement
9. 012 Smile.Communications Reports Financial Results for Q4 and Full Year 2007
10. Harris Corporation Demonstrates Digital Signage(TM) Solutions for Dynamic, Rapid Communications within Healthcare Enterprises
11. Avaya Unified Communications Solutions Help Healthcare Organizations Address Multi-Site, Mobile Workforce Challenges
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2015)... May 28, 2015 According to ... http://www.idataresearch.com ), the shoulder reconstruction device market, was ... bone & joint market in 2014. This trend ... procedures in the U.S. due to increased surgeon ... technology resulting in greater patient outcomes. Therefore, surgeons ...
(Date:5/28/2015)... The connected car is gaining more traction ... vehicles have some iteration of a connected offering in ... insurance companies as the data collected can be used ... insurance (UBI). This is the primary reason that 800+ ... 2015 Conference & Exhibition. , Andrew Pym, TU ...
(Date:5/28/2015)... lifeIMAGE announced today that ... led by Cambia Health Solutions (Portland, Ore.), ... health care by creating a person-focused and economically sustainable ... for exchanging medical imaging, will use this financing to ... breadth of its network capabilities and implement the next ...
(Date:5/28/2015)... A bucket list should include dreams, goals, destinations, ... the bucket list can be tiny, small, medium, large, ... owner wants to happen in their own lifetime. ... to making this list. Bucket list ideas might ... seeing the Grand Canyon on horseback, skydiving, visiting Scotland, ...
(Date:5/28/2015)... May 28, 2015 The MIT Sloan ... study featuring Healthcare IQ. Members of the MIT CISR ... management team to develop the case study about Healthcare ... analytics. , The case study, ‘Healthcare IQ: Competing as ... from its beginning as a hospital financial software provider ...
Breaking Medicine News(10 mins):Health News:DePuy Synthes and Biomet Lead Fastest Growing U.S. Shoulder Reconstruction Device Market 2Health News:DePuy Synthes and Biomet Lead Fastest Growing U.S. Shoulder Reconstruction Device Market 3Health News:TU-Automotive: North America’s Leading Insurers Head to Chicago as Connected Car Motor Insurance Shifts up a Gear 2Health News:TU-Automotive: North America’s Leading Insurers Head to Chicago as Connected Car Motor Insurance Shifts up a Gear 3Health News:Cambia Health Solutions Leads New Round of Investment in lifeIMAGE 2Health News:Cambia Health Solutions Leads New Round of Investment in lifeIMAGE 3Health News:Cambia Health Solutions Leads New Round of Investment in lifeIMAGE 4Health News:Healthcare IQ, the “Switzerland” of Healthcare Spend Analytics, Featured in MIT Case Study 2Health News:Healthcare IQ, the “Switzerland” of Healthcare Spend Analytics, Featured in MIT Case Study 3
... of Monte Carlo Dose Calculation Software Announced ... Radiation Oncology Meeting in Barcelona, BARCELONA, Spain, Sept. ... leader in the field of radiosurgery,announced today that its ... the U.S. Food and Drug Administration and is,now commercially ...
... Severe Bleeding, BETHESDA, Md., Sept. 10 A ... in moderate to severe wounds has received FDA clearance ... news for soldiers,and civilians alike, because the product is ... "The FDA,s speedy approval of WoundStat means that ...
... DaVita Inc.,(NYSE: DVA ) announced today that ... Partners, Inc. for approximately $65 million in cash.,HomeChoice, based ... services to patients with acute or chronic conditions that ... suite. HomeChoice has reported,approximately $37 million in trailing twelve ...
... healthcare,providers follow proven protocols could reduce the risks ... to a study reported in,a cardiovascular surgery supplement ... A study of the American Heart Association,s Get ... how hospitals carry out,many of the association,s secondary ...
... and MPRO Honor Hospital Excellence, KALAMAZOO, Mich., ... received the Governor,s Award for Improving Patient,Safety and ... addition, 29,Critical Access hospitals statewide received the Governor,s ... in the Critical Access,Hospital Setting. The Governor presents ...
... 10 Give an Hour, a,non-partisan, non-profit organization ... their loved ones, announces that there are 575,providers, ... Armed Forces,and their families., In an effort ... the military through the military health care system, ...
Cached Medicine News:Health News:Accuray Receives FDA Clearance for New Dose Calculation Technique for Body Radiosurgery 2Health News:Accuray Receives FDA Clearance for New Dose Calculation Technique for Body Radiosurgery 3Health News:Accuray Receives FDA Clearance for New Dose Calculation Technique for Body Radiosurgery 4Health News:Accuray Receives FDA Clearance for New Dose Calculation Technique for Body Radiosurgery 5Health News:Life-Saving News for Battlefield Soldiers & Wounded Civilians 2Health News:Life-Saving News for Battlefield Soldiers & Wounded Civilians 3Health News:DaVita Acquires Majority Stake in HomeChoice Partners, Inc. 2Health News:American Heart Association Surgical Supplement Journal Report: Appropriate Hospital Discharge System Can Prevent Future Cardiac Events 2Health News:American Heart Association Surgical Supplement Journal Report: Appropriate Hospital Discharge System Can Prevent Future Cardiac Events 3Health News:American Heart Association Surgical Supplement Journal Report: Appropriate Hospital Discharge System Can Prevent Future Cardiac Events 4Health News:Michigan Hospitals Receive Governor's Award 2Health News:Michigan Hospitals Receive Governor's Award 3Health News:National Non-Profit Organization Offers Free Mental Health Services to Military and Military Families 2
(Date:5/28/2015)... 28, 2015  Based on its ongoing analysis ... recognizes Lexmark Healthcare with the 2015 ... of the Year in Healthcare Content Management. In ... next level of interoperability and cost efficiency, Lexmark ... up with large-scale product development and portfolio integration ...
(Date:5/28/2015)... , May 28, 2015  Freedom Meditech, Inc., a ... chronic diseases from current blood-based standards to early and ... $4.8 million in a Series C financing. The company ... $14 million since founded. The company has also appointed ... and a member of the company,s board of directors. ...
(Date:5/28/2015)... 2015   Clementia Pharmaceuticals, Inc. today ... second part (Part B) of its natural history ... a rare, severely disabling congenital myopathy characterized by ... that result in the formation of new, abnormal ... The multi-center, non-interventional, two-part longitudinal study ...
Breaking Medicine Technology:Frost & Sullivan Acknowledges Lexmark Healthcare's Energy, Creativity, and Diligence in Developing the Leading Next-Generation Healthcare Content Management Platform 2Frost & Sullivan Acknowledges Lexmark Healthcare's Energy, Creativity, and Diligence in Developing the Leading Next-Generation Healthcare Content Management Platform 3Frost & Sullivan Acknowledges Lexmark Healthcare's Energy, Creativity, and Diligence in Developing the Leading Next-Generation Healthcare Content Management Platform 4Frost & Sullivan Acknowledges Lexmark Healthcare's Energy, Creativity, and Diligence in Developing the Leading Next-Generation Healthcare Content Management Platform 5Freedom Meditech Raises $4.8 Million and Appoints John Gerace as Chief Executive Officer 2Freedom Meditech Raises $4.8 Million and Appoints John Gerace as Chief Executive Officer 3Freedom Meditech Raises $4.8 Million and Appoints John Gerace as Chief Executive Officer 4Clementia Advances Natural History Study of Patients with Fibrodysplasia Ossificans Progressiva 2Clementia Advances Natural History Study of Patients with Fibrodysplasia Ossificans Progressiva 3
... Reported Safety & Tolerability Profile,in Subjects with ... CHICAGO, June 25 /PRNewswire-FirstCall/ -- Phase III ... of the American Diabetes,Association demonstrated that saxagliptin, ... Bristol-Myers,Squibb Company (NYSE: BMY) and AstraZeneca (NYSE: ...
... Findings Reported Safety & Tolerability Profile,in Subjects ... --, CHICAGO, June 25, 2007 /PRNewswire-FirstCall/ -- ... annual meeting of the American Diabetes,Association demonstrated ... development by Bristol-Myers,Squibb Company and AstraZeneca , ...
Cached Medicine Technology:Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 2Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 3Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 4Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 5Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 6Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 2Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 3Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 4Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 5Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic,Control in Subjects with Type 2 Diabetes Compared to Metformin,Alone 6
... Analyzer provides youwith new, exciting possibilities for ... WASCA Analyzeranalyzes the optical properties of the ... retina. In addition to refractive values, the ... which were largely ignored in the past. ...
... air flow modules are the economic solution ... work areas, which nevertheless present all the ... The modules can be easily installed in ... necessary to create sterile environment, without modifications ...
BRAT 2 Autologous Blood Recovery System gives performance, speed, versatility, and quality processing. , ,The BRAT 2 is now available with on-board Vacuum, programmability, plasma sequestration, Data...
The Wixson Hip Positioner is used for stable positioning of a patient during total hip and revision surgery. It is designed to be placed on top of the operating table....
Medicine Products: