Navigation Links
When erectile dysfunction isn't whole story
Date:8/23/2011

NEW YORK (Aug. 23, 2011) -- For men with erectile dysfunction (ED), 65 percent are unable to have an orgasm and 58 percent have problems with ejaculation, according to new research led by physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center.

The study followed 12,130 men with mild to severe ED and is the largest-ever analysis of orgasmic and ejaculatory dysfunction. Results are published in today's edition of the British Journal of Urology International.

Approximately 30 million American men, or half of all men aged 40 to 70, have trouble achieving or sustaining an erection. "While medications like Viagra or Cialis have been successful in helping many of these men, our research suggests there are other common sexual issues that remain largely unaddressed," says Dr. Darius Paduch, the study's lead author; male sexual medicine specialist at NewYork-Presbyterian Hospital/Weill Cornell Medical Center; and assistant professor of urology and reproductive medicine at Weill Cornell Medical College.

"We must expand the definition of quality of life when it comes to sexual performance," Dr. Paduch adds. "For the last few decades, we have focused on penile rigidity, with erection as a synonym of normal sexual function. However, many patients say that problems with ejaculation -- like decreased force or volume or decreased sensation of orgasm -- are just as critical.

"Despite the frequency of these issues, non-erectile sexual dysfunction is underreported and undertreated due to social stigma and misunderstandings about the physiology of male sexual response and orgasmic dysfunction in particular. For decades it was believed that only women had problems with orgasm; our study shows that orgasmic dysfunction could be as prevalent among men as it is among women."

While severity of dysfunctional ejaculation and orgasm correlated with ED severity, says Dr. Paduch, these issues were still surprisingly common in men with very mild ED: Orgasm dysfunction was reported by 26 percent in this group, and ejaculation dysfunction by 18 percent. "This suggests that non-erectile sexual dysfunction is a regular occurrence even in men without ED."

The study reported factors associated with increased risk of ejaculatory and orgasmic dysfunction which includes commonly prescribed antidepressant medications. Ejaculatory and orgasmic dysfunction can be caused by low testosterone and minor brain injury such as that sustained by motor vehicle accident victims, football players suffering from concussion, or by soldiers with combat-related blast head injuries.

The most common ejaculatory dysfunction is premature ejaculation, but the condition also describes delayed ejaculation, inability to ejaculate, painful ejaculation, retrograde ejaculation, as well as a reduced volume of ejaculate or diminished force of ejaculation. Orgasm dysfunction is defined as absence of an orgasm.

In the current study, Dr. Paduch and Alexander Bolyakov, a research associate at Weill Cornell Medical College, in collaboration with a research team from Eli Lilly and Company, analyzed questionnaires from 28 clinical trials of men with mild to moderate erectile dysfunction from a diverse, international cohort of patients enrolled in clinical trials for tadalafil (Cialis).

The study was supported by an educational grant from Eli Lilly and Company. Dr. Paduch and Bolyakov are paid investigators and/or consultants/advisers/speakers for the study sponsor. Additional co-authors included Dr. Anthony Beardsworth and Steven D. Watts -- both from Eli Lilly.

Going forward, Dr. Paduch and Bolyakov will use uniquely specialized equipment available in their lab at Weill Cornell to measure biological and subjective changes that occur in men during orgasm and ejaculation. They will look at whether testosterone-replacement therapy can help men who suffer from non-erectile sexual dysfunction.

"Sexual satisfaction is known to be linked to the likelihood of orgasm, which in turn affects emotional intimacy and relationship satisfaction. The high prevalence of both orgasmic and ejaculatory dysfunction warrants further clinical and translational research into new treatments to improve sexual health and overall quality of life for hundreds of thousands of affected men and their loved ones," says Dr. Paduch.


'/>"/>

Contact: Takla Boujaoude
tab2016@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

Related medicine news :

1. Antioxidants of growing interest to address infertility, erectile dysfunction
2. Non-steroidal anti-inflammatory drugs linked to increased risk of erectile dysfunction
3. Link established between erectile dysfunction and calcified coronary arteries
4. Drug now used to treat erectile dysfuncton may enhance delivery of herceptin to certain brain tumors
5. Preoperative MRI assists in surgical planning and helps spare erectile function after RALP
6. Real Men Don't Take Erectile Dysfunction Drugs Without a Prescription
7. Erectile Dysfunction Plus Heart Disease Raises Death Risk
8. Home Care Delivered, Inc. Launches a New Vacuum Therapy Category to Service Patients with Erectile Dysfunction
9. An unhealthy lifestyle is associated with sexual dysfunction
10. The New York Academy of Sciences to host a symposium on cognitive dysfunction in multiple sclerosis
11. Dietary inorganic nitrate may reduce heart dysfunction caused by powerful anti-cancer drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the ... Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , “We ... new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice ...
(Date:6/25/2016)... ... , ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department ... in recognition of their exemplary accomplishments in worksite health promotion. , The Wellness at ... Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was one of 42 ...
(Date:6/24/2016)... ... , ... Those who have experienced traumatic events may suffer from a complex ... as drug or alcohol abuse, as a coping mechanism. To avoid this pain and ... a traumatic event. , Trauma sufferers tend to feel a range of emotions, from ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension ... that it will receive two significant new grants to support its work to ... its 25th anniversary by recognizing patients, medical professionals and scientists for their work ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is ... Road To Recovery® program to drive cancer patients to and from their cancer treatments. ... the highest quality of life and ongoing independence. Getting to and from medical ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Mass. , June 24, 2016   Pulmatrix, ... pharmaceutical company developing innovative inhaled drugs, announced today that ... Russell Investments reconstituted its comprehensive set of ... "This is an important milestone for Pulmatrix," ... will increase shareholder awareness of our progress in developing ...
(Date:6/24/2016)... 24, 2016  Arkis BioSciences, a leading innovator ... more durable cerebrospinal fluid treatments, today announced it ... funding is led by Innova Memphis, followed by ... private investors.  Arkis, new financing will accelerate the ... market release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Market - Forecast to 2022" report to their offering. ... method for the patients with kidney failure, it replaces the ... from the patient,s blood and thus the treatment helps to ... chloride in balance. Increasing number of ESRD ...
Breaking Medicine Technology: