Navigation Links
When erectile dysfunction isn't whole story
Date:8/23/2011

NEW YORK (Aug. 23, 2011) -- For men with erectile dysfunction (ED), 65 percent are unable to have an orgasm and 58 percent have problems with ejaculation, according to new research led by physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center.

The study followed 12,130 men with mild to severe ED and is the largest-ever analysis of orgasmic and ejaculatory dysfunction. Results are published in today's edition of the British Journal of Urology International.

Approximately 30 million American men, or half of all men aged 40 to 70, have trouble achieving or sustaining an erection. "While medications like Viagra or Cialis have been successful in helping many of these men, our research suggests there are other common sexual issues that remain largely unaddressed," says Dr. Darius Paduch, the study's lead author; male sexual medicine specialist at NewYork-Presbyterian Hospital/Weill Cornell Medical Center; and assistant professor of urology and reproductive medicine at Weill Cornell Medical College.

"We must expand the definition of quality of life when it comes to sexual performance," Dr. Paduch adds. "For the last few decades, we have focused on penile rigidity, with erection as a synonym of normal sexual function. However, many patients say that problems with ejaculation -- like decreased force or volume or decreased sensation of orgasm -- are just as critical.

"Despite the frequency of these issues, non-erectile sexual dysfunction is underreported and undertreated due to social stigma and misunderstandings about the physiology of male sexual response and orgasmic dysfunction in particular. For decades it was believed that only women had problems with orgasm; our study shows that orgasmic dysfunction could be as prevalent among men as it is among women."

While severity of dysfunctional ejaculation and orgasm correlated with ED severity, says Dr. Paduch, these issues were still surprisingly common in men with very mild ED: Orgasm dysfunction was reported by 26 percent in this group, and ejaculation dysfunction by 18 percent. "This suggests that non-erectile sexual dysfunction is a regular occurrence even in men without ED."

The study reported factors associated with increased risk of ejaculatory and orgasmic dysfunction which includes commonly prescribed antidepressant medications. Ejaculatory and orgasmic dysfunction can be caused by low testosterone and minor brain injury such as that sustained by motor vehicle accident victims, football players suffering from concussion, or by soldiers with combat-related blast head injuries.

The most common ejaculatory dysfunction is premature ejaculation, but the condition also describes delayed ejaculation, inability to ejaculate, painful ejaculation, retrograde ejaculation, as well as a reduced volume of ejaculate or diminished force of ejaculation. Orgasm dysfunction is defined as absence of an orgasm.

In the current study, Dr. Paduch and Alexander Bolyakov, a research associate at Weill Cornell Medical College, in collaboration with a research team from Eli Lilly and Company, analyzed questionnaires from 28 clinical trials of men with mild to moderate erectile dysfunction from a diverse, international cohort of patients enrolled in clinical trials for tadalafil (Cialis).

The study was supported by an educational grant from Eli Lilly and Company. Dr. Paduch and Bolyakov are paid investigators and/or consultants/advisers/speakers for the study sponsor. Additional co-authors included Dr. Anthony Beardsworth and Steven D. Watts -- both from Eli Lilly.

Going forward, Dr. Paduch and Bolyakov will use uniquely specialized equipment available in their lab at Weill Cornell to measure biological and subjective changes that occur in men during orgasm and ejaculation. They will look at whether testosterone-replacement therapy can help men who suffer from non-erectile sexual dysfunction.

"Sexual satisfaction is known to be linked to the likelihood of orgasm, which in turn affects emotional intimacy and relationship satisfaction. The high prevalence of both orgasmic and ejaculatory dysfunction warrants further clinical and translational research into new treatments to improve sexual health and overall quality of life for hundreds of thousands of affected men and their loved ones," says Dr. Paduch.


'/>"/>

Contact: Takla Boujaoude
tab2016@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

Related medicine news :

1. Antioxidants of growing interest to address infertility, erectile dysfunction
2. Non-steroidal anti-inflammatory drugs linked to increased risk of erectile dysfunction
3. Link established between erectile dysfunction and calcified coronary arteries
4. Drug now used to treat erectile dysfuncton may enhance delivery of herceptin to certain brain tumors
5. Preoperative MRI assists in surgical planning and helps spare erectile function after RALP
6. Real Men Don't Take Erectile Dysfunction Drugs Without a Prescription
7. Erectile Dysfunction Plus Heart Disease Raises Death Risk
8. Home Care Delivered, Inc. Launches a New Vacuum Therapy Category to Service Patients with Erectile Dysfunction
9. An unhealthy lifestyle is associated with sexual dysfunction
10. The New York Academy of Sciences to host a symposium on cognitive dysfunction in multiple sclerosis
11. Dietary inorganic nitrate may reduce heart dysfunction caused by powerful anti-cancer drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... ... April 28, 2017 , ... Woolsy Corporation Limited, ... through its Nova Skin Sciences division, recently announced the launch of Allumière Antiaging ... the power of an anti-aging concentrate. , Anogeissus Leiocarpa Bark Extract ...
(Date:4/27/2017)... and DENVER (PRWEB) , ... April 27, 2017 ... ... Health, the nation’s leading respiratory hospital, based in Denver, Colorado, announced an agreement ... is enabled by the continuing support of the Jane and Leonard Korman Family ...
(Date:4/27/2017)... ... April 27, 2017 , ... Last night, Christine Collins ... the Year for her extraordinary compassion and lifelong dedication to serve others. Since ... caregivers for the prestigious award each year – identifying a CAREGiver who has ...
(Date:4/27/2017)... ... 2017 , ... Plastic Surgery Associates is excited to announce that Heather Furnas, ... upcoming Aesthetic Meeting. Held in San Diego, at the San Diego Convention Center, the ... their expertise to the Premier Global Hot Topics session, speaking on genital rejuvenation. , ...
(Date:4/26/2017)... (PRWEB) , ... April 26, 2017 , ... ... set that describes the adoption of e-prescribing as measured in Part D Medicare ... prescribers deliver prescriptions to pharmacies, either using e-prescribing, faxes or paper. The ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... , April 20, 2017 Research and Markets ... - Innovation Driven by Rapidly Expanding Injectables Market and Increasing Usage ... offering. ... drug delivery technologies will rise from USD 20 Billion in 2015 ... Global Drug Delivery Technologies - Innovation Driven by Rapidly Expanding Injectables ...
(Date:4/20/2017)... , April 20, 2017 ... platform, the first non-viral gene expression technology that enables ... the eye to address a wide range of ophthalmic ... Medicines and Healthcare products Regulatory Agency (MHRA) to advance ... ...
(Date:4/19/2017)... -- The Mobile X-Ray product segment is the most attractive ... forecast period Mobile X-Ray segment is the largest ... devices market, which is estimated to be valued at more ... of 7% over the forecast period. Mobile X-Ray segment is ... 100 Mn in 2017 over 2016. The segment,s revenue in ...
Breaking Medicine Technology: