Navigation Links
What's in your water?: Disinfectants create toxic by-products
Date:3/31/2009

Although perhaps the greatest public health achievement of the 20th century was the disinfection of water, a recent study now shows that the chemicals used to purify the water we drink and use in swimming pools react with organic material in the water yielding toxic consequences.

University of Illinois geneticist Michael Plewa said that disinfection by-products (DBPs) in water are the unintended consequence of water purification. "The reason that you and I can go to a drinking fountain and not be fearful of getting cholera is because we disinfect water in the United States," he said. "But the process of disinfecting water with chlorine and chloramines and other types of disinfectants generates a class of compounds in the water that are called disinfection by-products. The disinfectant reacts with the organic material in the water and generates hundreds of different compounds. Some of these are toxic, some can cause birth defects, some are genotoxic, which damage DNA, and some we know are also carcinogenic."

The 10-year study began with an EPA grant to develop mammalian cell lines that would be used specifically to analyze the ability of these compounds to kill cells, or cytotoxicity, and the ability of these emerging disinfection by-products to cause genomic DNA damage.

"Our lab has assembled the largest toxicological data base on these emerging new DBPs. And from them we've made two fundamental discoveries that hopefully will aid the U.S. EPA in their regulatory decisions. The two discoveries are somewhat surprising," Plewa said.

The first discovery involves iodine-containing DBPs. "You get iodine primarily from sea water or underground aquifers that perhaps were associated with an ancient sea bed at one time. If there is high bromine and iodine in that water, when you disinfect these waters, you can generate the chemical conditions necessary to produce DBPs that have iodine atoms attached. And these are much more toxic and genotoxic than the regulated DBPs that currently EPA uses," he said.

Plewa said that the second discovery concerns nitrogen-containing DBPs. "Disinfectant by-products that have a nitrogen atom incorporated into the structure are far more toxic and genotoxic, and some even carcinogenic, than those DBPs that don't have nitrogen. And there are no nitrogen-containing DBPs that are currently regulated."

In addition to drinking water DBPs, Plewa said that swimming pools and hot tubs are DBP reactors. "You've got all of this organic material called 'people' -- and people sweat and use sunscreen and wear cosmetics that come off in the water. People may urinate in a public pool. Hair falls into the water and then this water is chlorinated. But the water is recycled again and again so the levels of DBPs can be ten-fold higher than what you have in drinking water."

Plewa said that studies were showing higher levels of bladder cancer and asthma in people who do a lot of swimming - professional swimmers as well as athletic swimmers. These individuals have greater and longer exposure to toxic chemicals which are absorbed through the skin and inhaled.

"The big concern that we have is babies in public pools because young children and especially babies are much more susceptible to DNA damage in agents because their bodies are growing and they're replicating DNA like crazy," he said.

Some public pools have been closed because they have high levels of bacteria. "Public pools keep a high level of chlorine in the water to keep bacteria and pathogens down but very little work research is conducted on evaluating levels of generated dangerous disinfection by-products.

"The idea is to keep the pools disinfected, keep them in compliance, just as with drinking water but then use engineering techniques that reduce the levels of these toxic by-products." Plewa described another project he is working on as a researcher with a National Science Foundation Center called WaterCAMPWS at the University of Illinois. "We're working with engineers and chemists to develop new technologies that will disinfect water, that will desalinate water, that will remove pharmaceuticals from water but in so doing, don't generate by-products that are even more toxic than the things you're trying to remove."

Ironically, the DBPs that are regulated by the EPA tend to be some of the least toxic DBPs in Plewa's study. "We've found that the emerging DBPs are much more genotoxic and much more cytotoxic. But I can't fault EPA because these data were not present at the time and in fact the development of the database of over 70 DBPs has been done in concert with our colleagues at the federal EPA."

Plewa said that until new technologies are engineered to safely disinfect the water in public pools, education is needed to encourage people to bathe or shower before entering a public pool. "It's the organic material that gets in the pool that is disinfected and then recirculated over and over again. That's why we call swimming pools disinfectant by-product reactors. But by public education, by personal behavior, there should be ways that we can reduce the levels of the dissolved organic material that should reduce the level of DBPs."

Plewa, along with a team of scientists received a United States Environmental Protection Agency Science and Technology award for their paper Occurrence, genotoxicity and carcinogenicity of regulated and emerging disinfection by-products in drinking water: A review and roadmap for research. It was published in the scientific journal Mutation Research.


'/>"/>

Contact: Debra Levey Larson
dlarson@illinois.edu
217-244-2880
University of Illinois at Urbana-Champaign
Source:Eurekalert

Related medicine news :

1. Fact Sheet Explains Cleaners, Disinfectants
2. PURE Bioscience Announces Brazilian Regulatory Approval for SDC-Based Hospital-Grade Disinfectants
3. Not all risk is created equal
4. S.C. BlueCross Creates Corporate Planning Unit, Promotes Davis to Vice President
5. TriWest Creates First-of-its-Kind Partnership to Offer Military Leaders With Grief Support Program
6. Mother and Daughter Create Lead-Free/Safe Bibs and Solve Messy Mealtime Problems
7. Braun Challenges Business School Talent To Create A Buzz
8. Exceptional Childrens Foundation Merger with Kayne Eras Center Creates One of States Most Comprehensive Nonprofits Serving the Disabled
9. MEDEX Global Group & Harvard Medical International Join Forces to Create the Most Comprehensive Health Information Resource for International Travelers
10. New Case Study Details How an Illinois Hospital Created a Safe Lifting Team that Dramatically Reduced Injuries, Increased Staff Satisfaction
11. Penn Veterinary Medicine report new strategy to create genetically modified animals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... Dothan, AL (PRWEB) , ... December 02, 2016 ... ... leaders from across the Dothan-Wiregrass Area in Alabama are expected to attend the ... Mike Schmitz, will help provide scholarship funds for area students and operating support ...
(Date:12/2/2016)... (PRWEB) , ... December 02, 2016 , ... The annual ... Enrollment Period (or Annual Election Period), is ending December 7th. Currently-enrolled Medicare beneficiaries who ... C) or prescription drug plan (Part D) need to make changes during this period ...
(Date:12/2/2016)... Hills, CA (PRWEB) , ... December 02, 2016 ... ... reconstructive surgeon in Beverly Hills, California, will be included in the 2016 “Guide ... given to exceptional professionals based on the amalgamation of their education, experience, and ...
(Date:12/2/2016)... , ... December 02, 2016 , ... ... the Hyatt Regency Waikiki Beach Resort and Spa in Honolulu, offering local frontline ... field of pain management. , The demand for supplemental training related to ...
(Date:12/2/2016)... Texas (PRWEB) , ... December 02, 2016 , ... Yisrayl ... that delves into how this current generation fits into Bible Prophecy. Yisrayl says this ... various facts pointing to this conclusion, showing how the details line up exactly with ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... DUBLIN , Dec 2, 2016 Research ... Pipeline Database" newsletter to their offering. ... , , ... La Merie Publishing,s proprietary R&D Drug Pipeline Database provides 24/7 online ... therapeutic drugs on the market and on investigational drug candidates in ...
(Date:12/2/2016)... the largest share in the ECG Cables And ECG Leadwires ... remote monitoring ECG devices. On the other hand, the ... the highest growth rate during the forecast period. ... Company (U.S.), Medtronic plc ( Ireland ), Koninklijke ... Medical International Limited ( China ), held major ...
(Date:12/2/2016)... Quantum Radiology,s Mobile Breast Center (QR MBC) brings cutting-edge ... at the workplace, thereby maximizing convenience and compliance.  QR ... and SunTrust Bank, and community health groups to provide ... "I think it,s a great service for ... a mammogram without taking a large amount of time ...
Breaking Medicine Technology: